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RU58841 showed promise for treating androgenic alopecia but research was halted due to financial and organizational changes. There were no significant safety concerns reported in human trials.

This conversation is about a user named "mr_mime125" who experienced results from using topical finasteride (0.1%) and minoxidil (5%) solution 1.5 ml twice a day for the first two months followed by just minoxidil (5%) 1 ml once a day in the last month, resulting in a drastic improvement to their hairline. Other users discussed their progress while asking questions and offering encouragement.

A user shared their successful hair regrowth routine, which includes finasteride, derma rolling, minoxidil (Rogaine), biotin pills, and vitamin D supplementation, and saw noticeable results in 3 months. They suggest this routine as a variation of the "Big 3" hair loss treatments and have created a website to sell the products they used.

Long-term use of finasteride and dutasteride may be linked to health risks like fatty liver disease, insulin resistance, type 2 diabetes, dry eye disease, and potential kidney disease. Some users believe the risks are low and the medications are generally safe.

A user is frustrated with long-term hair loss despite using Dutasteride and Ketoconazole shampoo. Suggestions include trying oral Minoxidil, micro-needling, and a homemade caffeinated rosemary tonic.

Finasteride's long-term risks are often exaggerated; studies showing negative effects typically involve high doses or animal subjects. For those taking 1mg daily for hair loss, there is no significant evidence of severe side effects.

Long term Finasteride users and whether or not they have noticed improvements after two years of use, with other treatments such as Minoxidil and dermarolling also discussed. Some replies suggest that improvement is possible even beyond the two year mark while others caution against believing studies backed by the Post-Finasteride Foundation.

Long-term finasteride users report maintaining hair and experiencing regrowth, with some using it for over 20 years. Combining finasteride with minoxidil or hair transplants can improve results.

Long-term finasteride and minoxidil user shares tips for dealing with hair loss, including finding a shorter hairstyle, using finasteride, and not obsessing over hair. Users discuss washing frequency, alternative treatments, and focusing on other aspects of life.

A user is considering using minoxidil for hair loss and asks for advice on application and long-term effectiveness. Responses suggest minoxidil can be effective but may lose efficiency over time, and combining it with other treatments like finasteride might be more beneficial.

A 19-year-old concerned about long-term effects of 5AR inhibitors on physical appearance. They have used finasteride and plan to try dutasteride or RU58841; responses suggest improved skin, hair, and confidence.

A user with early-stage diffuse hair thinning asked for long-term success stories using treatments like finasteride, minoxidil, and RU58841. One person regained most of their hair after 22 months on finasteride and minoxidil, while another saw significant improvement with oral minoxidil after trying various treatments over many years.

Hair loss treatments RU55841, CB-03-01, and Eucapil were discussed, with concerns about needing increased dosages over time and potential side effects. A user suggested that CB's results could be due to various factors and that combining it with finasteride might slow down any upregulation.

The conversation is about the long-term safety trial results for pyrilutamide, which are expected soon. Treatments mentioned include Minoxidil, finasteride, and RU58841.

Testing the effectiveness of Verteporfin as a potential treatment for hair loss, with users discussing their thoughts on its long-term results. Treatments mentioned include Minoxidil, Finasteride, and RU58841.

The potential health risks associated with long-term use of finasteride and dutasteride, with some responses pointing out the low quality of the journal that published the review article as well as highlighting other alternatives such as keto or minoxidil, and RU58841.

A user is experiencing significant hair loss and scalp issues despite using Minoxidil, finasteride, and RU58841 since 2017. They switched to oral Minoxidil and are now on isotretinoin and topical corticosteroids for seborrheic dermatitis but continue to lose hair and seek advice on whether inflammation or treatment changes are the cause.

The conversation discusses hair loss treatments, specifically the use of minoxidil, finasteride, and microneedling, and the experience of shedding hair as a potential sign of treatment effectiveness. Some users report positive results after initial shedding, while others express concerns about long-term hair loss and the effectiveness of treatments.

A user shared their 4-year hair loss journey, highlighting that switching from topical to oral minoxidil and finasteride, along with dermarolling, significantly improved their hair growth. Another user mentioned using dutasteride, and the original poster emphasized the importance of dermarolling.

Pumpkin seed oil may help maintain hair and improve the crown area. Head massages are also considered beneficial.

Over 5 years, the user saw hair improvement using finasteride and dermarolling, but experienced hair loss with weightlifting. Recently increased finasteride dose and is more careful with dermarolling, but is not considering minoxidil.

Long-term efficacy of dermarolling with minoxidil is discussed for hair loss treatment. User can't use RU, Fin, or topical Fin due to side effects and considers using finasteride with an aromatase inhibitor as a last resort.

People switching from Finasteride to Dutasteride after long-term use of finasteride and their results, including hair maintenance and increased thickness.

A user discussed their doctor lowering their Minoxidil dose from 5mg to 2.5mg, expressing concerns about losing hair gains. Other users suggested that 2.5mg is safer long-term and speculated the doctor is being cautious about side effects.

A user with long-term hair loss has been using topical minoxidil, finasteride, RU58841, ketoconazole, and dermastamping for 8 months. They are unsure if the new hairs are miniaturized or vellus.

The conversation discusses long-term hair loss treatment, with one person seeing hair darkening after 3 years using Minoxidil, Finasteride, and Dutasteride, and others sharing their shorter-term experiences with similar treatments. They emphasize that hair regrowth takes time and to not expect quick results.

A user shared their long-term struggle with hair loss and various treatments, including Minoxidil, biotin, and dermarolling. They also discussed a disappointing experience with a hair health institute that provided dubious recommendations and expensive remedies.

A woman discovered her long-term hair loss was due to undiagnosed anemia, with ferritin levels as low as 9. After starting iron supplements, she saw significant hair regrowth, especially in previously bald areas, though some spots remain unchanged.

The conversation discusses the long-term results of using finasteride, RU58841, and minoxidil for hair loss, with some skepticism about the truthfulness of the results and a reference to a scam involving RU58841.

Hydrocortisone is not recommended for long-term use on the scalp due to potential side effects like thinning and steroid-related issues. Alternatives like foam minoxidil or oral minoxidil are suggested, though foam may be less effective.