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      community 15 months into trying to regrow my hair

      in Update  18 upvotes 5 years ago
      The user has been treating hair loss for 15 months using a regimen that includes 5% minoxidil, dermarolling, a dermpen, a topical mix of 3% minoxidil with 0.1% finasteride, Wild-Growth hair oil, pumpkin seed and peppermint oil, Nizoral or Nioxin shampoo, multivitamins, and cod liver oil. They have not seen noticeable changes recently and are seeking motivation to start working out again.

      community 2.5mg dut safety/price/synergy w/topical fin

      in Finasteride/Dutasteride  3 upvotes 9 months ago
      The conversation discusses the safety and cost of 2.5mg Dutasteride, and the potential for increased DHT reduction by combining Dutasteride with topical Finasteride. The original poster is currently using 0.5mg Dutasteride, 1.25mg oral Minoxidil, and a topical treatment, and is considering increasing the dosage to maximize results while avoiding less known treatments like RU58841.

      community Could topical min work if oral min didn’t?

      in Minoxidil  3 upvotes 11 months ago
      The conversation is about whether topical Minoxidil could be effective for hair loss if oral Minoxidil did not work, considering the addition of microneedling and tretinoin. The user has tried oral Minoxidil for over a year without results and is seeking advice on alternative treatments.

      community People who used cyproterone for hair loss

      in Treatment  2 upvotes 1 year ago
      The conversation discusses the use of 12.5mg cyproterone every other day for hair loss. There's a concern about reducing testosterone potentially increasing DHT and negatively affecting hair.

      community A hair model who does beauty ads and has 3 million followers claims he went from almost a Norwood 3 to a perfect hairline in 8 months on only Minoxidil and Rosemary oil. Curious, what are people’s thoughts?

      in Chat 1 year ago
      This conversation discusses the results of a model who claims he went from almost a Norwood 3 to a perfect hairline in 8 months using only Minoxidil and Rosemary oil. The replies suggest that this could be realistic but long-term results would require additional treatments like finasteride or other medications to prevent further hair loss.

      community Pyrilutamide is literally my only hope

      in Chat  91 upvotes 2 years ago
      Considering treatments for hair loss, including Minoxidil, Finasteride, RU58841, Fluridil and Pyrilutamide. The user is weighing the risks of taking unapproved medication before it has been mass produced.

      community 1.5yrs Fin 5m Min.. wow it was bad

      in Progress Pictures  250 upvotes 2 weeks ago
      The user experienced significant hair improvement using 1mg finasteride and 2.5mg oral minoxidil daily, with most gains attributed to finasteride. They also stopped using topical treatments due to scalp psoriasis and reported no major side effects.

      community Bile Acid-Mediated DHT Dysregulation Hypothesis

      in Research/Science  13 upvotes 3 weeks ago
      Elevated bile acids can inhibit the enzyme AKR1C2, leading to increased DHT levels, which may accelerate hair loss in those predisposed to androgenetic alopecia. Treatments mentioned include topical minoxidil and finasteride.

      community Oral min vs topical comparison

      in Treatment  10 upvotes 1 month ago
      Oral minoxidil is claimed to be more effective and easier to use than topical minoxidil, with a 100% response rate, but it may cause unwanted body hair growth and has potential heart-related side effects. Topical minoxidil is less effective for many due to enzyme limitations, can cause scalp issues, and is more challenging to apply, but it avoids systemic side effects.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 3 months ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community Ordered copper peptides - how to apply?

      in Treatment  1 upvotes 3 months ago
      Gizzela is unsure about the dosage and frequency of copper peptides and asks if they can be used with Stemoxydine. They seek advice on applying these treatments together.

      community NootBro Recommendations… How Do We Feel

      in Research/Science  9 upvotes 5 months ago
      The conversation is about hair loss treatments, specifically a stack including topical Ashwagandha, Copper Peptide, Gotu Kola, Ketoconazole, and PDA. One user found Topical and Sub-Q GHK-CU effective.

      community Mechanism of action of alfatradiol (17 alpha estradiol)

      in Research/Science  6 upvotes 6 months ago
      The conversation discusses the mechanism of action of alfatradiol (17 alpha estradiol) in treating hair loss. It explores theories that it either inhibits 5 alpha reductase to prevent T->DHT conversion or aromatizes scalp T into 17-alpha-estradiol to save hair.

      community What do you think about this topical formula?

      in Finasteride/Dutasteride  3 upvotes 6 months ago
      The conversation discusses a topical formula for hair loss including Finasteride (0.025%), Minoxidil (0.5%), Tretinoin (0.01%), Caffeine (0.005%), Melatonin (0.003%), Tea Tree Oil (0.05%), Aloe (0.05%), Biotin (0.05%), and Fagron TrichoXidil (2.5%). The user considers removing Minoxidil and Tretinoin to test TrichoXidil's effectiveness.

      community How to correctly dose Saw Palmetto and Pumpkin Seed Oil

      in Research/Science  5 upvotes 7 months ago
      The user takes 1 mg finasteride three times a week, topical minoxidil daily, and Saw Palmetto both topically and orally on non-finasteride days. They recently added 1 g of pumpkin seed oil daily to improve hair thickness and are seeking advice on dosing and cycling Saw Palmetto.

      community Why isn’t oral minoxidil enough for me?

      in Minoxidil  7 upvotes 8 months ago
      A user takes 5mg oral minoxidil, oral dutasteride, topical tretinoin, stemoxydine, topical minoxidil, and uses dermarolling for hair loss but sees less impressive, patchy regrowth compared to others. Another person suggests some online results may be enhanced with hair fibers, not just medication.

      community Treating my DUPA via controlling inflammation

      in Treatment  6 upvotes 9 months ago
      The user has DUPA and suspects autoimmune activity as a cause. They have tried various treatments including finasteride, minoxidil, dutasteride, pyrilutamide, estrogel, hydrocortisone, and clobetasol, and are now seeking a long-term immunosuppressant.

      community important questions about RU58841

      in Research/Science  3 upvotes 11 months ago
      The user has been using finasteride for hair loss and is considering adding RU58841. They ask about RU58841's effectiveness, potential heart side effects, duration of action, dosage increase over time, transitioning to GT20029, and where to find the liquid form.