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GlossaryHepatotoxicity (Liver damage)

refers to liver damage caused by chemicals or drugs

Hepatotoxicity, also known as liver toxicity, refers to liver damage caused by chemicals, drugs, or natural substances. It can result in a range of liver dysfunctions, from mild enzyme elevations to severe liver failure. This condition is significant in both clinical and pharmacological contexts, as the liver plays a crucial role in metabolizing substances, and its impairment can lead to serious health consequences.

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community Will my liver get destroyed long term on this stack ??

in Chat 15 upvotes 9 months ago

A user is considering a long-term hair loss treatment stack including Dutasteride, Finasteride, and oral Minoxidil, and is concerned about potential liver damage. Some responses suggest the stack is excessive, while others believe it's not harmful to the liver, but recommend regular blood work to monitor health.

community Dutasteride broked my liver (maybe)

in Finasteride/Dutasteride 8 upvotes 1 year ago

A user shared their experience with high cholesterol, glucose, and potential metabolic syndrome after using Finasteride and Dutasteride for hair loss. They plan to improve their health with diet and exercise before considering medication.

community Attention Finasteride / Dutasteride and Your liver

in Finasteride/Dutasteride 367 upvotes 3 weeks ago

Finasteride may cause elevated liver enzymes, potentially leading to liver issues, though this is rare. Users should monitor liver function and consider topical alternatives if liver sensitivity occurs.

community Dutasteride High Libido. How come we don't talk about this?

in Finasteride/Dutasteride 204 upvotes 1 month ago

Dutasteride and finasteride can affect libido differently, with some experiencing increased libido and others decreased libido or erectile dysfunction. Dutasteride may increase testosterone levels but can also cause side effects like liver enzyme changes, while topical finasteride may have fewer sexual side effects.

community 1.5yrs Fin 5m Min.. wow it was bad

in Progress Pictures 250 upvotes 1 week ago

The user experienced significant hair improvement using 1mg finasteride and 2.5mg oral minoxidil daily, with most gains attributed to finasteride. They also stopped using topical treatments due to scalp psoriasis and reported no major side effects.

community New Dutasteride Long Term Study (5 years) it works.

in Finasteride/Dutasteride 106 upvotes 1 year ago

The conversation discusses a five-year study on dutasteride, a medication for male hair loss. The study found that 89.9% of patients saw improvement or prevention of hair loss progression, with varying success rates based on different balding patterns. Side effects were mostly sexual and decreased over time. Dutasteride was concluded to be a long-term, safe, and effective treatment for male hair loss.

community How much would a high dose dutasteride scalp dht inhibition be?

in Finasteride/Dutasteride 10 upvotes 7 months ago

The conversation discusses the potential for high doses of dutasteride to completely inhibit scalp DHT and speculates whether this could cure baldness when combined with a topical antiandrogen. Specific dosages mentioned are 0.5 mg reducing scalp DHT by 55% and 2.5 mg by about 79%.

community Shedding and thinning won’t stop on Nuclear protocol

in Treatment 21 upvotes 1 year ago

The user is using a combination of hair loss treatments including dutasteride, minoxidil, RU58841, low-level laser therapy, ketokonozole, supplements, Viviscal, Nutrafol, microneedling, PRP, and scalp Botox injections, but is still experiencing hair shedding and thinning. Despite being on this regimen for two years, the user's hair condition is worsening, and they are seeking advice on what else they can do.

community I’m just Going to let Nature take its Course

in Chat 213 upvotes 1 year ago

The post and conversation are about a 23-year-old deciding to stop using finasteride for hair loss due to potential erectile dysfunction risks, sparking a debate about the benefits and side effects of hair loss treatments.

community Finasteride/dut. causes NAFLD,IR,diabetes,kidney dysfunction is it correct.

in Finasteride/Dutasteride 139 upvotes 1 year ago

Hair loss discussion mentions treatments like Finasteride, Dutasteride, and Minoxidil. Users share experiences, side effects, and advice on using these treatments.

community treatment of Bicalutamide low dose weekly?

in Treatment 6 upvotes 2 years ago

The conversation is about using bicalutamide, taken less frequently than daily, for hair loss treatment. The user is considering 50mg every 3 days or once a week and is asking for others' experiences.

community Minoxidil Finasteride heart problems

in Update 97 upvotes 6 months ago

A user experienced heart problems after taking 1mg finasteride and 2.5mg oral minoxidil and is considering quitting minoxidil. Others discussed their experiences with heart issues and minoxidil, with some suggesting topical minoxidil as a safer alternative.

community I’m going balls to the wall with probably the most nuclear stack apart from hormone blockers, will update this thread monthly.

in Treatment 52 upvotes 2 years ago

A user experimenting with an extreme hair loss treatment stack of Dutasteride, RU58841, 15 mg oral minoxidil, and microneedling, which sparked a debate among other users about the safety of this approach.

community RU-58841 Lung Disease Possibility | Chest pain, "heart issues", etc

in Treatment 24 upvotes 8 months ago

Some users of RU-58841 report cardiovascular symptoms like heart palpitations and chest tightness, which may be linked to its metabolites causing lung disease. The safety of RU-58841 is uncertain due to lack of long-term data and concerns about product purity, especially from gray market sources.

community Is DUT better or worse than FIN?

in Finasteride/Dutasteride 62 upvotes 1 year ago

The conversation discusses the effectiveness of Dutasteride (DUT) and Finasteride (FIN) for hair loss. Users share varied experiences, with some finding DUT more effective and others experiencing side effects or no change, highlighting that individual responses can vary.

community Is ketoconazole shampoo bullshit?

in Ketoconazole 45 upvotes 1 year ago

The conversation is about the effectiveness of ketoconazole shampoo for hair loss. The conclusion is that ketoconazole shampoo can help with dandruff and seborrheic dermatitis, but it is not a strong enough treatment to stop or regrow hair. It is recommended to use it as an adjunct treatment along with finasteride or dutasteride.

community Does Ashwagandha cause hair loss?

in Chat 24 upvotes 1 year ago

User asks if Ashwagandha causes hair loss while using Finasteride and Minoxidil. Replies suggest Ashwagandha may increase shedding, but raising testosterone within normal levels likely won't significantly affect hair loss.

community Some finasteride and minoxidil gains.

in Progress Pictures 379 upvotes 1 year ago

Doug-Sweeney has had positive results from using 1mg of finasteride and 5% minoxidil applied twice a day to treat his hair loss. Other users have also commented on how Doug-Sweeney looks younger with the improvements in hair quality.

community Extreme regimen and still miniaturized hairs. AGA is just impossible to beat.

in Insane 35 upvotes 1 year ago

A user's extreme regimen for hair loss, which includes taking oral and topical medications such as minoxidil, dutasteride, cyproterone acetate and bicalutamide, but still experiencing miniaturization. Suggestions were made to try other treatments such as RU58841 and Pyrilutamide, while also considering mental health treatment and advice on lookmaxxing.

community ‘ Health Risks Associated with Long-Term Finasteride and Dutasteride Use: It’s Time to Sound the Alarm’ Thoughts? Concerns?

in Finasteride/Dutasteride 66 upvotes 3 years ago

The potential health risks associated with long-term use of finasteride and dutasteride, with some responses pointing out the low quality of the journal that published the review article as well as highlighting other alternatives such as keto or minoxidil, and RU58841.

community I started rapidly diffuse thinning at 22. I'm 42 now and have as much hair as I did at 16. AMA

in Treatment 445 upvotes 4 years ago

Hair loss treatments like finasteride, minoxidil, ketoconazole, PRP, and microneedling helped maintain hair for 20 years. Research and try evidence-based treatments for best results.

community Progress: 3 months min 4 times a week/dermaroll twice a week/antigray shampoo

in Is this regrowth? 126 upvotes 1 year ago

The post discusses hair regrowth progress after 3 months of using Minoxidil four times a week, dermarolling twice a week, and using an anti-gray shampoo. The conversation includes speculation about the effectiveness of the shampoo, with some users noting visible darkening and growth of hair.

community Is this true? Is long term taking fin harmful to the liver?

in Chat 127 upvotes 10 months ago

The conversation discusses whether long-term use of finasteride (Fin) is harmful to the liver, with various opinions on side effects and comparisons to other substances. Specific treatments mentioned include finasteride, minoxidil (Min), and RU58841 (RU).

community Male pattern baldness, and mental health

in Finasteride/Dutasteride 330 upvotes 9 months ago

A 48-year-old man has been using minoxidil for 15 years and considered finasteride but stopped due to potential side effects. He is concerned about his mental health and the impact of hair loss on self-image, and he encourages support among men experiencing hair loss.

community Leaving Ketoconazole Shampoo on for Longer

in Ketoconazole 15 upvotes 6 months ago

The conversation is about using Ketoconazole shampoo for hair loss, with users discussing leaving it on the scalp for longer periods. Some users report benefits for dandruff, but there's uncertainty about its effectiveness for androgenetic alopecia (AGA).

community Going to try and reverse MPB naturally.

in Treatment 55 upvotes 2 years ago

A user is trying to reverse male pattern baldness (MPB) naturally by taking high doses of Vitamin D, improving diet, exercising, reducing stress, and other lifestyle changes, but plans to use finasteride if no results are seen in 60 days. Other users are skeptical, advising medical treatments like finasteride and warning against potential vitamin D overdose and the ineffectiveness of natural remedies for genetic hair loss.

community Reminder : Biotin is useless (expect if you are really deficient, and you're not)

in Chat 103 upvotes 2 years ago

Biotin supplements are not effective for hair loss unless you are actually deficient, which is rare. Some users report improved hair quality with biotin, but there's no evidence supporting its use for hair loss in healthy individuals.

community My personal results (M/25) 0.5mg Fin daily, Min foam once a day (in the evening) and Keto Shampoo twice a week. The before photo was taken in 2019 as I didn't plan to document the progress.

in Progress Pictures 922 upvotes 3 years ago

User shared personal hair loss treatment results using 0.5mg Fin daily, Min foam once a day, and Keto Shampoo twice a week. Significant improvement was observed, with others impressed and asking questions about the treatment.

community Nuclear Stack Ineffective: Oral DUT/FIN/MIN/RU - NAFLD?

in Finasteride/Dutasteride 1 upvotes 4 months ago

The user experienced severe hair shedding despite using oral finasteride, minoxidil, dutasteride, and RU58841, and was diagnosed with Non-Alcoholic Fatty Liver Disease (NAFLD). They are considering switching to topical treatments due to the ineffectiveness of their current regimen.

community What are these spots on my scalp

in Treatment 51 upvotes 4 months ago

A user noticed non-itchy, non-bleeding spots on their scalp while experiencing hair loss. Replies suggest the spots are likely sunspots or liver spots and recommend seeing a dermatologist; hair loss is attributed to male pattern baldness.