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GlossaryCirrhosis

chronic liver disease marked by scarring and impaired function

Cirrhosis, also known as liver cirrhosis or hepatic cirrhosis, is a chronic liver disease characterized by the replacement of healthy liver tissue with scar tissue, leading to impaired liver function. This condition can result from various causes, including chronic alcohol abuse, hepatitis infections, and non-alcoholic fatty liver disease, and it can lead to complications such as liver failure, portal hypertension, and increased risk of liver cancer.

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community How much would a high dose dutasteride scalp dht inhibition be?

in Finasteride/Dutasteride 10 upvotes 8 months ago

The conversation discusses the potential for high doses of dutasteride to completely inhibit scalp DHT and speculates whether this could cure baldness when combined with a topical antiandrogen. Specific dosages mentioned are 0.5 mg reducing scalp DHT by 55% and 2.5 mg by about 79%.

community Just find a cure already, I am totally done

in Chat 161 upvotes 4 months ago

The conversation is about hair loss treatments, with users recommending finasteride and minoxidil as effective solutions. Some users report side effects, but overall, the consensus is to use these treatments rather than waiting for a cure.

community Minoxidil Finasteride heart problems

in Update 97 upvotes 7 months ago

A user experienced heart problems after taking 1mg finasteride and 2.5mg oral minoxidil and is considering quitting minoxidil. Others discussed their experiences with heart issues and minoxidil, with some suggesting topical minoxidil as a safer alternative.

community Attention Finasteride / Dutasteride and Your liver

in Finasteride/Dutasteride 370 upvotes 1 month ago

Finasteride may cause elevated liver enzymes, potentially leading to liver issues, though this is rare. Users should monitor liver function and consider topical alternatives if liver sensitivity occurs.

community Imo everyone should take serrapeptase for a short extended period to break up scar tissue in their scalp

in Research/Science 1 year ago

Treatments for hair loss, such as Minoxidil, Finasteride and RU58841, as well as using serrapeptase to break up scar tissue in the scalp.

community HAHAHAHHAHA WTF DUDE I CAN’t even escape hairloss for like an hour , just hoped on league to witness this , btw “Finasteride 5mg”totally carried the game i hope the actual drug carries us too.😂

in Chat 826 upvotes 11 months ago

The conversation jokes about hair loss treatments, mentioning finasteride, minoxidil, dutasteride, microneedling, ketoconazole shampoo, and rosemary oil as if they were players in a game. Some users also discuss the use of finasteride for prostate issues and the possibility of splitting the dose.

community Will my liver get destroyed long term on this stack ??

in Chat 15 upvotes 10 months ago

A user is considering a long-term hair loss treatment stack including Dutasteride, Finasteride, and oral Minoxidil, and is concerned about potential liver damage. Some responses suggest the stack is excessive, while others believe it's not harmful to the liver, but recommend regular blood work to monitor health.

community Dutasteride broked my liver (maybe)

in Finasteride/Dutasteride 8 upvotes 2 years ago

A user shared their experience with high cholesterol, glucose, and potential metabolic syndrome after using Finasteride and Dutasteride for hair loss. They plan to improve their health with diet and exercise before considering medication.

community PSA: My GP told me you should get yearly kidney and liver tests if you are on Dutasteride

in Update 15 upvotes 6 months ago

Dutasteride users should get yearly kidney and liver tests, especially young people. General health checkups are not common in the UK, but such tests are recommended as a precaution.

community ‘Long term use of fin/dut may be associated with health risks including fatty liver disease, insulin resistance, type 2 diabetes, dry eye disease and potential kidney disease.’

in Research/Science 22 upvotes 5 months ago

Long-term use of finasteride and dutasteride may be linked to health risks like fatty liver disease, insulin resistance, type 2 diabetes, dry eye disease, and potential kidney disease. Some users believe the risks are low and the medications are generally safe.

community Is this true? Is long term taking fin harmful to the liver?

in Chat 127 upvotes 11 months ago

The conversation discusses whether long-term use of finasteride (Fin) is harmful to the liver, with various opinions on side effects and comparisons to other substances. Specific treatments mentioned include finasteride, minoxidil (Min), and RU58841 (RU).

community Connection between finasteride and nafld?

in Research/Science 4 upvotes 4 months ago

Finasteride may affect liver function and cortisol levels, potentially linking it to non-alcoholic fatty liver disease (NAFLD). More research is needed to understand this connection fully.

community How does finasteride leave your body?

in Chat 13 upvotes 8 months ago

Finasteride is metabolized in the liver and excreted through urine and feces. Users humorously discuss its excretion, with one joking about it being expelled through ejaculation.

community Hair transplant histamine issues (could be antibiotics taken during transplant!?)

in Transplants 1 upvotes 1 year ago

User experienced severe allergic reactions and liver issues after a hair transplant, likely due to antibiotics and medications. Despite trying Minoxidil, the user faced further complications and is now seeking medical advice for potential future transplants.

community Anyone experienced weight gain on dutasteride?

in Finasteride/Dutasteride 6 upvotes 2 years ago

Dutasteride can lead to increased cholesterol and liver fat. The user is reconsidering its use due to high cholesterol and lipid levels despite a healthy lifestyle.

community M27 Fin/Min (topical) was fun while it lasted

in Finasteride 126 upvotes 3 months ago

The user experienced significant hair regrowth using topical Minoxidil and Finasteride but had to stop due to high liver enzyme levels. They plan to pause treatment for a month to see if their liver values return to normal.

community Would Salicylic Acid shampoo hinder Oral Minoxidil? Like topical?

in Research/Science 3 upvotes 1 year ago

Salicylic Acid shampoo may hinder topical minoxidil but not oral minoxidil, which works through the liver. The user plans to continue using oral minoxidil and is concerned about the shampoo's effect on it.

community I want to know more about hair growth and vitamin D

in Chat 10 upvotes 1 year ago

People discussed vitamin D deficiency and its link to hair loss. One user added cod liver oil to their regimen to boost vitamin D.

community So is sublingual topical minoxidil not as effective as oral?

in Minoxidil 8 upvotes 3 years ago

Topical liquid minoxidil may be safe to consume in small amounts, but it needs liver processing to become effective for hair growth. Therefore, oral pills might be more effective.

community A warning to those using or thinking about using Dutasteride – Follow-up

in Finasteride/Dutasteride 18 upvotes 3 years ago

The post and conversation are about the long-term side effects of using Dutasteride and Finasteride for hair loss, including issues like raised liver enzymes, high cholesterol, and loss of libido. The user advises regular blood work and careful monitoring for those using these treatments.

community A warning to those thinking about using Dutasteride

in Finasteride/Dutasteride 99 upvotes 4 years ago

The potential risks of long-term use of Dutasteride and how it may be linked to elevated liver enzymes, cholesterol levels, and decreased testosterone. Alternative treatments such as Finasteride and RU58841 were also discussed.

community Dutasteride High Libido. How come we don't talk about this?

in Finasteride/Dutasteride 207 upvotes 2 months ago

Dutasteride and finasteride can affect libido differently, with some experiencing increased libido and others decreased libido or erectile dysfunction. Dutasteride may increase testosterone levels but can also cause side effects like liver enzyme changes, while topical finasteride may have fewer sexual side effects.

community What Private blood test should I take?

in Finasteride/Dutasteride 7 upvotes 4 months ago

A user in the UK seeks advice on blood tests before starting Finasteride and Minoxidil for hair loss. Recommended tests include thyroid function, hormone levels, liver and kidney function, and vitamin and mineral levels.

community Started taking 2.5mg Dut about a month ago

in Technology 17 upvotes 5 months ago

A user started taking 2.5mg Dutasteride for hair loss, along with oral Minoxidil, and is concerned about liver impact. Other users warn about the high dosage and potential health risks.

community What are these spots on my scalp

in Treatment 51 upvotes 5 months ago

A user noticed non-itchy, non-bleeding spots on their scalp while experiencing hair loss. Replies suggest the spots are likely sunspots or liver spots and recommend seeing a dermatologist; hair loss is attributed to male pattern baldness.

community Nuclear Stack Ineffective: Oral DUT/FIN/MIN/RU - NAFLD?

in Finasteride/Dutasteride 1 upvotes 5 months ago

The user experienced severe hair shedding despite using oral finasteride, minoxidil, dutasteride, and RU58841, and was diagnosed with Non-Alcoholic Fatty Liver Disease (NAFLD). They are considering switching to topical treatments due to the ineffectiveness of their current regimen.

community Topical fin working when oral has failed?

in Finasteride/Dutasteride 1 upvotes 6 months ago

The user switched from oral finasteride to dutasteride with minoxidil, but saw no results. They then tried topical finasteride and noticed some potential improvement after four months, theorizing that the topical application bypasses liver metabolism.

community Sublingual Minoxidil - Cure to Hairloss?

in Minoxidil 583 upvotes 1 year ago

The conversation discusses the potential benefits of sublingual minoxidil for hair loss treatment. It suggests that sublingual minoxidil, which bypasses the liver, may have fewer side effects, greater bioavailability, and could be more effective than oral minoxidil.

community Topical Finasteride Doesn't Directly Reduce 5ar Enzyme on Scalp

in Finasteride/Dutasteride 72 upvotes 1 year ago

Topical Finasteride doesn't directly reduce 5ar enzyme on scalp and has the same mechanism as oral, needing to go through the liver. Users debate the accuracy of this information and discuss various studies and experiences.

community 5ARI (dutasteride) Associated with Adverse Metabolic Effects

23 upvotes 6 years ago

Dutasteride is associated with increased blood glucose, HbA1c, LDL cholesterol, and liver enzyme activity, potentially leading to diabetes, NAFLD, and liver metabolism changes. The conversation highlights concerns about these adverse effects and calls for more studies, including on finasteride.