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      community GT20029 China Phase II Trial For AGA Reached Primary Endpoint

      in Research/Science  134 upvotes 10 months ago
      The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.

      community Anyone have experience with latanoprost topical?

      in Treatment  1 upvotes 1 year ago
      The post discusses the use of latanoprost foam for hair growth, with the user expressing concerns about its efficiency and safety. The user is currently using topical dutasteride, which maintains their hair but doesn't promote regrowth, and is seeking a product that doesn't affect hormone levels.

      community Is RU558841 actually related to heart issues?

      in Finasteride/Dutasteride  11 upvotes 1 week ago
      RU58841 may cause heart-related side effects like palpitations and chest pain, though evidence is mostly anecdotal. Users report mixed experiences, with some stopping due to side effects and others using it without issues, but concerns about its safety and sourcing remain.

      community Question about medications ...

      in Finasteride/Dutasteride  2 upvotes 4 months ago
      Hair loss treatments like spironolactone often require lifelong use to maintain results. Stopping the medication can lead to increased testosterone levels and potential hair loss.

      community Is ketoconazole very effective?

      in Ketoconazole  10 upvotes 8 months ago
      A user is considering using ketoconazole shampoo for hair loss and is seeking feedback on its effectiveness. They are asking for before and after photos or success stories.

      community Topical Dutasteride. Does it work?

      in Finasteride/Dutasteride  13 upvotes 8 months ago
      Topical dutasteride may be effective for hair loss by staying in the scalp and minimizing bloodstream absorption, potentially improving hair results and reducing side effects. The user seeks advice on its effectiveness.

      community 4 month progress (23M) on the Big 3. [NW7 when I started, I think]

      in Progress Pictures  164 upvotes 1 year ago
      A 23-year-old man shared his 4-month hair regrowth progress using 1mg oral finasteride daily, 5% minoxidil with finasteride topical twice a day, multivitamins, microneedling, head massages, and ketoconazole shampoo. He's unsure of his current Norwood scale classification and is asking for help to determine it, with suggestions ranging from NW4 to NW4.5.

      community Is there a consensus on a "best conditioner" to use?

      in Research/Science  12 upvotes 1 year ago
      The conversation is about finding the best conditioner for hair loss, with a mention that Ketoconazole shampoo is recommended for reversing hair loss. Users suggest that most "hair growth" conditioners are ineffective and discuss using anti-dandruff conditioners with piroctone olamine.

      community M 20 | 5M Fin / 2.5M Min | Progress

      in Progress Pictures  48 upvotes 1 year ago
      A user's successful hair loss treatment using ketoconazole shampoo, 0.5mg finasteride, and 5% liquid minoxidil. They noticed significant results after 4 months, with reduced hair fall observed earlier.

      community I've been afflicted by post finasteride syndrome, what now?

      in Finasteride  42 upvotes 6 years ago
      A user experienced severe side effects from finasteride, including mental health issues and physical symptoms, and sought advice on managing post-finasteride syndrome. Suggestions included checking vitamin levels, considering dopamine agonists, and avoiding further psychiatric medications.

      community is anyone using ru58841 against acne?

      in Technology  3 upvotes 1 month ago
      RU58841 is discussed as a potential treatment for acne and hair loss, with users debating its effectiveness and safety compared to other treatments like finasteride, minoxidil, and dutasteride. Concerns about RU58841's side effects and lack of clinical trials are raised, while some users share their personal experiences and routines involving RU58841 for hair loss.

      community KX-826 seems to be working for me

      in Product  1 upvotes 2 months ago
      KX-826 stopped hair loss for the user after stopping finasteride due to mild side effects. The user experienced mild headaches initially with KX-826, which resolved after a few days.

      community How essential is scalp biopsy when dealing with hair loss?

      in Treatment  6 upvotes 4 months ago
      The user experienced hair loss despite using Fin and Min for 12 years and switched to Dutasteride, RU58841, and Keto scalp serum, but shedding and itch persist. They are considering increasing Dutasteride to 2.5mg and questioning the necessity of a scalp biopsy, with mixed opinions on its usefulness.

      community Opinions- AGA options and pregnancy

      in Female  7 upvotes 6 months ago
      A user with Androgenetic Alopecia is seeking advice on hair growth treatments while planning for pregnancy. Current routine includes LaserCap, Nizoral Shampoo, scalp massage, The Ordinary Multi Peptide Serum, vitamin D, prenatal vitamins, and SEEN shampoo.

      community Question for Russians in this subreddit

      in Product  1 upvotes 6 months ago
      The user plans to switch to oral finasteride and oral minoxidil due to insufficient results from PRP, topical minoxidil, and mild DHT inhibitors. They seek advice on purchasing these medications from My.India, questioning its trustworthiness.

      community My boy Saul Goodman was on Minoxidil tabs too

      in Satire  1916 upvotes 6 months ago
      Saul Goodman was humorously depicted using high doses of minoxidil, finasteride, and spironolactone for hair loss. The conversation jokes about the unrealistic dosages and their potential side effects.

      community Topical Minoxodil vs Oral Minoxodil

      in Minoxidil  91 upvotes 9 months ago
      A user has been using topical minoxidil and finasteride for hair loss but is considering switching to oral minoxidil due to the inconvenience of topical application. Another user cautions that switching forms may cause shedding and that oral minoxidil may have different side effects and results.

      community Pointless to use ketoconazol 1%

      in Ketoconazole  6 upvotes 1 year ago
      The conversation is about the ineffectiveness of 1% ketoconazole for hair loss, with the user stating that studies support the 2% version and even that has minimal results. The user also mentions using minoxidil, which dries out their scalp, and ketoconazole worsens it.

      community Hope Medicine HMI-115 got 28M$ investment

      in Research/Science  60 upvotes 1 year ago
      Hope Medicine received a $28M investment for HMI-115, a monoclonal antibody in phase II trials for treating androgenetic alopecia. Some users are skeptical about its effectiveness, while others find the investment and trial results encouraging.

      community Testosterone in Reference Range Doesn't Cause Hair Loss

      in Research/Science  51 upvotes 1 year ago
      Testosterone within the normal range does not significantly contribute to male pattern baldness (MPB); DHT is the main factor that can be controlled. Genetics play a crucial role in hair loss, and treatments like finasteride and dutasteride, which block DHT, can help despite potentially raising testosterone levels.