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      community The Cure isn't 5 years away; it's already here.

      in Research/Science  1005 upvotes 1 year ago
      PP405 is a new topical treatment for hair loss, showing promise in trials but still requires finasteride for maintenance. There is skepticism about its effectiveness and safety, with concerns about needing finasteride to maintain results.

      community Question about mixing different topical solutions. Is this something ok to do?

       1 upvotes 2 years ago
      The user is mixing various topical solutions for hair loss, including Dutasteride, Minoxidil, Finasteride, tretinoin, RU58841, Stemoxydine, and Reviv AHK-Cu, and is questioning if this practice is effective or wasteful. They are concerned about potential interactions, especially with the new treatment KX-826, which should not be mixed with Minoxidil.

      community I have experienced some regrowth at age 30

       57 upvotes 1 month ago
      A user experienced hair regrowth at age 30 using caffeine and capixyl topical treatments, scalp massages, ketoconazole shampoo, and by discontinuing a water softener. They are hesitant to start oral minoxidil due to potential side effects and are not interested in using finasteride.

      community Been off Tressless for a few years - what’s the latest on GT20029?

       17 upvotes 1 month ago
      GT20029 is an experimental topical treatment for male-pattern hair loss, showing promising results in Phase 2 trials and moving towards Phase 3. It aims to degrade androgen receptors in hair follicles, differing from treatments like finasteride and minoxidil.

      community 2-3 Years Hair Regrowth Progress Pictures

       855 upvotes 4 months ago
      The user showed 2-3 years of hair regrowth progress using oral finasteride, topical minoxidil, and microneedling. They plan to switch to oral dutasteride and Liposomal Minoxidil Sulfate for better results.

      community Almost 4 months, before and after of pyrilutamide .5% once daily

       23 upvotes 4 months ago
      The user experienced significant hair regrowth using a combination of minoxidil, alfatradiol, pyrilutamide, and nizoral, despite previous intolerance to finasteride. They emphasize the importance of consistency in treatment and are optimistic about the results, noting no side effects so far.

      community Zero Progress on dutasteride :(

       60 upvotes 5 months ago
      The user is frustrated with minimal hair regrowth after using dutasteride, oral minoxidil, and previously finasteride and topical minoxidil. Despite feeling discouraged, others suggest continuing treatment as progress can be slow and subtle, with some users noting visible improvement.

      community Hair loss is holding me back from enjoying life and I'm wasting away my youth

       279 upvotes 5 months ago
      A 31-year-old man feels depressed due to hair loss, using topical finasteride and previously tried minoxidil. Others suggest treatments like finasteride, minoxidil, hair transplants, or embracing baldness, highlighting the importance of mental health and self-acceptance.

      community Haircafe slams pp405 presentation. Are results really that bad?

       64 upvotes 5 months ago
      PP405 shows promise in activating dormant hair follicles and increasing hair counts but lacks detailed efficacy data compared to minoxidil and finasteride. Opinions are mixed, with some optimism and skepticism about its effectiveness.

      community 6 months on minoxidil shedding again

       269 upvotes 5 months ago
      A user experienced hair shedding after six months of using topical minoxidil and is considering adding finasteride to their routine. Many suggest that minoxidil alone is insufficient for stopping hair loss and recommend combining it with finasteride or dutasteride for better results.

      community KX-826 Phase 3 Results Are Out

       121 upvotes 6 months ago
      KX-826 shows promising results for hair growth with fewer side effects, offering an alternative to finasteride and minoxidil. Users discuss combining it with minoxidil, dermarolling, and Nizoral for improved results.

      community Clascoterone - what we have right now

       24 upvotes 6 months ago
      Clascoterone is a topical treatment for androgenetic alopecia, showing modest to moderate hair regrowth, and may be available by 2027-2028. It is considered safer than finasteride, with discussions on its effectiveness compared to RU58841 and pyrilutamide.

      community Why does hairloss look great one day and regression the next?

      in Chat  49 upvotes 7 months ago
      Hair appearance fluctuates due to factors like styling, product buildup, and humidity, causing frustration for those with diffuse thinning. Treatments mentioned include minoxidil, finasteride, ketoconazole shampoo, and RU58841, with mixed results.

      community I am losing hope and starting to think this is a scam

      in Minoxidil  39 upvotes 8 months ago
      The user is frustrated with hair loss treatments like finasteride, minoxidil, dutasteride, and oral minoxidil, which have been ineffective and caused scalp itching. They are skeptical about these treatments' effectiveness and consider alternative options like ketoconazole shampoo and RU58841.

      community PP405 Update and My Take on Pelage

      in Research/Science  86 upvotes 10 months ago
      Pelage Pharmaceuticals raised $120M for their hair loss treatment, PP405, showing strong investor confidence despite limited data. There is skepticism about its efficacy and long-term effects compared to treatments like GT20029.

      community I cannot even tolerate Nutrafol

      in Product  6 upvotes 10 months ago
      The user experienced side effects from finasteride and Nutrafol, opting for non-hormonal treatments like minoxidil, exercise, and a healthy lifestyle. Others discussed using Dutasteride, Biotin, and minoxidil with varying success and side effects.

      community One year on finasteride has reversed some aging

      in Chat  198 upvotes 11 months ago
      Finasteride and minoxidil use resulted in a more youthful appearance and improved skin. There is debate about their effects on collagen and skin aging, with no solid evidence supporting significant changes due to finasteride.

      community Oral Dut/Minoxidil for two years - no results.

       102 upvotes 11 months ago
      The user has used oral Dutasteride and Minoxidil for two years without regrowth, despite trying Finasteride and supplements. They consider increasing Minoxidil, adding microneedling, and switching medications, while others suggest RU58841, a hair transplant, or checking for other hair loss causes.

      community My experience fighting hairloss for 2 years

      in Chat  5 upvotes 1 year ago
      The person experienced worsening hair loss despite using minoxidil, finasteride, and dutasteride. They are considering increasing dutasteride dosage, trying microneedling, RU58841, and oral minoxidil, and are advised to consult a trichologist.

      community Won’t pp405 and gt20029 be patented and be almost unreasonably expensive

       29 upvotes 1 year ago
      Concerns about the potential high cost of new hair loss treatments, pp405 and gt20029, were discussed, with some users willing to pay a premium if they are effective. Alternatives like finasteride and minoxidil are mentioned as current, more affordable options, and there is speculation about future generic versions and black market availability.

      community Dutasteride is a Miracle Drug.

      in Finasteride/Dutasteride  250 upvotes 1 year ago
      Dutasteride is praised for improving skin and hair regrowth, with fewer side effects than finasteride. Users report mixed results on shedding and regrowth, with some experiencing enhanced libido and skin quality.