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GlossaryATP-sensitive potassium channels (KATP channels)

regulate potassium ion flow based on cellular energy levels

ATP-sensitive potassium channels (KATP channels) are specialized proteins found in the cell membrane that help regulate the flow of potassium ions in and out of the cell. These channels are sensitive to the levels of ATP (adenosine triphosphate), the cell's main energy currency, and they open or close in response to changes in ATP concentration. This mechanism allows the channels to play a crucial role in linking the cell's metabolic state to its electrical activity, which is important in various physiological processes such as insulin release, muscle contraction, and neuronal activity.

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community Physio-metabolic method of treating androgenic alopecia. Cold receptors. The relationship between DHT, cold receptors, minoxidil and antiandrogens.

in Research/Science 1 upvotes 2 weeks ago

A method for treating androgenic alopecia using minoxidil, antiandrogens, exercise, and cold exposure to promote hair growth. Environmental factors and lifestyle changes, like diet and exercise, can improve treatment effectiveness.

Physio-metabolic method of treating androgenic alopecia. Cold receptors. The relationship between DHT, cold receptors, minoxidil and antiandrogens

community Physio-metabolic method of treating androgenic alopecia. Cold receptors. The relationship between DHT, cold receptors, minoxidil and antiandrogens

in Research 413 upvotes 2 weeks ago

Treating androgenic alopecia with minoxidil, finasteride, and antiandrogens, alongside exercise, cryotherapy, and natural substances to stimulate cold receptors for better hair growth. The method focuses on enhancing treatment effectiveness by considering environmental and behavioral factors and the role of cold receptors and muscle stress.

community Update of my case, might have finally found what happened

in Minoxidil 6 upvotes 3 months ago

OP believes RU58841 affected their thyroid, causing hypothyroidism and impacting minoxidil's effectiveness. They plan to start thyroid medication to improve hair regrowth.

community KX-826: Long-Term Safety Results are out!

in Research/Science 156 upvotes 2 months ago

KX-826 initially improves hair growth but declines after 24 weeks, with mild itching as a side effect. Combining it with minoxidil and finasteride may improve results, but long-term effectiveness is uncertain.

community As in this research, i have seen many who advise a regular use of VitaminD, even if you are not deficient. Once i had read in tressless that mpb and Vitamin D might have a correlation. So could it be an a benefit to add this to your ongoing treatment plan?

in Research/Science 83 upvotes 4 years ago

People discussed using vitamin D supplements for hair loss, with some also using steroid injections, pumpkin seed oil, saw palmetto, and zinc. Despite supplementation, one user noted no improvement in hair condition, but acknowledged the general health benefits of addressing vitamin D deficiency.

community Pyrilutamide - your experience?

in Product 12 upvotes 1 year ago

The conversation is about the lack of improvement in hair loss after using Pyrilutamide for 14 weeks, with the original poster unable to use Finasteride due to depression. Replies suggest that Pyrilutamide, like RU58841, may not work for everyone, and a more potent drug is being developed by Kintor.

community Apparently I accidentally bought this, but how do I even use it? I have some K&B solution, rosemary oil (lmao) and castor oil. What do I put the powder in

in Product 5 months ago

The user accidentally bought a hair loss treatment and is seeking advice on how to use it with K&B solution, rosemary oil, and castor oil. They mention the phase 3 trial was disappointing but want to make use of the product.

community Why the fu*k do people behave like this?

in Chat 385 upvotes 1 year ago

People making comments on others' hair loss, and the different strategies used to deal with it. Treatments mentioned include finasteride and minoxidil.

community Isn’t Minixidilmax’s PG solvent just superior to the Anageninc K&B solvent

in Product 1 upvotes 5 months ago

PG solvent is considered superior to K&B solvent for RU58841 and Pyralutamide due to cost and effectiveness. The user questions why they should use K&B when PG offers more benefits.

community Has anyone tried Winlevi (a.k.a. Clascoterone or CB-03-01) on their scalp yet?

in Treatment 8 upvotes 3 years ago

The acne medication Winlevi, which contains Clascoterone, is available in the U.S. and may slow down hair loss until a higher concentration treatment, Breezula, is released.

community PG causing irritation when applying RU

in Research/Science 1 year ago

The user is experiencing irritation from using PG with RU58841 and is seeking alternative solutions like K&B in the UK. They report redness, itchiness, and flaky skin from the current treatment.

community Atherosclerosis as cause of balding and treatment

in Treatment 61 upvotes 1 year ago

Hair loss may be caused by calcification of capillaries in the scalp, restricting blood flow to hair follicles. A daily treatment regimen including high doses of Vitamins D and K, Magnesium, and Nattokinase could potentially decalcify these capillaries, improving blood flow and hair growth. However, some users warn against excessive Vitamin D intake and emphasize the need for medical consultation.

community Cumshotdiva II Drink min/Topical Min/MN/Just started fin/multivitamins/D3/Kvitamin /Tret/Keto

in Progress Pictures 16 upvotes 1 year ago

The user shared progress pictures and discussed using oral and topical Minoxidil, microneedling, recently starting finasteride, multivitamins, vitamin D3, vitamin K, tretinoin, and ketoconazole for hair loss. The conversation focuses on the effectiveness of these treatments.

community 3 month progress on Topical Minoxidil/Finasteride (Hims), oils, and derma-rolling

in Progress Pictures 2 years ago

This user has been using a combination of topical Minoxidil and Finasteride, oils, biotin, vitamins D and K, and derma-rolling for 3 months to help reduce hair loss. They have experienced some progress but are still looking for more recommendations from others.

community Thin spot isn't so thin anymore, but it's getting bigger. Is this a thing?

in Question 6 upvotes 5 years ago

A user is concerned about a growing thin spot on their boyfriend's head despite using Rogaine, Vitamin K, Vitamin E, Biotin, and Ubiquinol. Another user suggests starting finasteride, minoxidil, and dermarolling for better results.

community Anti Fibrosis and Calcification regimen?

in Question 10 upvotes 6 years ago

The user experienced no improvement in hair loss with finasteride and minoxidil but had side effects. They plan to add wounding, scalp massage, vitamin K, and taurine supplements to their regimen and seek feedback on these additions.

community I'm on multiple anti-androgens and after around year, my hairs are thinner, why?

in Finasteride/Dutasteride 16 upvotes 1 year ago

The user has been using finasteride, dutasteride, pyrithione zinc, and oral minoxidil to treat hair loss and has seen an increase in fine hairs on the hairline but overall thinning on the top. They are considering adding zinc and Vitamin K to their regimen and are already taking hair multivitamins with collagen.

community Rate my stack! (Using a nuclear protocol)

in Finasteride/Dutasteride 16 upvotes 3 years ago

A hair loss regimen involving Dutasteride, Oral Minoxidil, Mesotherapy, Topical Minoxidil/Finasteride, RU58841, Alfatridiol, Microneedling, LLLT, Keto shampoo, Vitamin K/D/Fish oil/Borage Oil/MSM, Oral Castor oil and Niacin. It also mentions products that have been dropped from the regimen due to not being worth the hassle or messing with libido.

community 3 Month Update – Topical Min (6%), Topical Fin (0.3%), 1.5mm Microneedle Weekly, 40 y/o

in Progress Pictures 99 upvotes 2 years ago

A user's 3-month update on their hair loss treatment, which consists of topical Minoxidil (6%), topical Finasteride (0.3%) and microneedling 1.5mm weekly; other users shared positive feedback and asked about the specifics of the treatments being used, such as product/brand, frequency, side effects and areas for microneedling.

community 3 Years on Fin, 1 Year on Dut.

in Progress Pictures 262 upvotes 1 month ago

The user switched from finasteride to dutasteride after experiencing significant hair shedding, and is also using oral minoxidil. Dutasteride helped stop the shedding, but it's too early to determine if it will reverse hair loss.

community Oral minoxidil 6 months update. Have I beaten the reaper yet?

in Satire 687 upvotes 4 months ago

The post and conversation discuss a user's 6-month update on using oral minoxidil for hair loss, with humorous and satirical replies. Some comments suggest discontinuing due to side effects.

community Major body hair loss from Finasteride (Also, just started oral minoxidil this week.)

in Finasteride/Dutasteride 6 upvotes 1 year ago

User experienced significant body hair loss from Finasteride and started oral Minoxidil to address crown thinning. Their current regimen includes 1mg Finasteride, 2.5mg Minoxidil, Biotin, Vitamin D, Zinc, Iron, and ketoconazole shampoo.

community Finasteride 5mg for female pattern hair loss

in Female 7 upvotes 4 years ago

The user's experience of using Finasteride 5mg and Aldactone 50mg to treat Female Pattern Hair Loss, as well as their use of PRP injections for further hair growth.

community 5+ Months Progress on Finasteride + Minoxidil 5% + Biotin And Derma Stamping

in Finasteride 6 upvotes 5 years ago

The user reported significant hair regrowth and thickening after 5 months using finasteride, minoxidil 5%, biotin, and derma stamping. They experienced some fatigue but no sexual side effects and plan to continue the treatment.

community Is this finasteride legitimate

in Finasteride/Dutasteride 2 upvotes 6 months ago

A user is concerned about the legitimacy of their finasteride from Simple Online Pharmacy. Another user notes similarities and differences with their own order from Dr. Fox but is unsure about the authenticity.

community 2 years progress. Fin and min and microneedling

in Progress Pictures 147 upvotes 10 months ago

The conversation discusses a user's two-year hair regrowth progress using finasteride, minoxidil, and microneedling. One user asks for a timeline of progress, another comments on hair length, and the original poster mentions using microneedling sporadically.

community Is 8% ru58841 significantly stronger than 5%

in Chat 19 upvotes 11 months ago

A user increased their RU58841 treatment from 5% to 8% to combat hair loss and is questioning the effectiveness of the higher dosage. Another user shared their extensive hair loss treatment regimen, suggesting that while 8% RU58841 might not significantly change results, it's worth trying as individual responses vary.

community Anageninc RU58841 is legit & my experience

in Research/Science 6 upvotes 1 year ago

The user experienced side effects from RU58841, including dry eyes and potential eyesight issues, and decided to stop using it. They confirmed the product's legitimacy but advised caution due to its experimental status and lack of safety data.

community Anyone have an alternative solvent for pyrilutamide??

in Product 2 upvotes 1 year ago

The user is seeking an alternative solvent for pyrilutamide due to skin irritation from ethanol and propylene glycol. They experienced similar issues with topical minoxidil.

community Vitamin Deficiency: “Severely” Low on Vitamin D

in Update 15 upvotes 1 year ago

A user experiencing significant hair loss found they had a severe vitamin D deficiency and was prescribed 50,000IU vitamin D pills, likely to be taken weekly. They are questioning if the deficiency could be the cause of their hair loss and if correcting it could stop the shedding and improve hair recovery.