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GlossaryInsulin-Lowering Medications (Insulin-Lowering Drugs)

drugs that reduce blood insulin levels

Insulin-Lowering Medications, also known as Insulin-Lowering Agents, are drugs designed to reduce the levels of insulin in the blood. These medications are often used to manage conditions like polycystic ovary syndrome (PCOS) and type 2 diabetes by improving insulin sensitivity and reducing insulin resistance, thereby helping to regulate blood sugar levels and mitigate associated symptoms.

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community Next month marks 2 years on Dutasteride. When does it start working?

in Finasteride/Dutasteride 36 upvotes 5 months ago

A user has been on dutasteride for nearly 2 years with no improvement in hair loss, expressing frustration. Other users suggest checking for other health conditions, getting bloodwork, and considering stopping TRT or trying finasteride.

community If we lose hair because of our sensitivity to DHT, then why are we trying to reduce DHT when our sensitive androgen receptors are the culprit?

in Finasteride/Dutasteride 13 upvotes 2 years ago

The conversation discusses the effectiveness of reducing DHT for hair loss treatment and explores alternative approaches like reducing androgen receptor sensitivity. Specific treatments mentioned include finasteride, dutasteride, pyrilutamide (KX-826), GT20029, and RU58841.

community hair loss treatment myths that perplex me

in Treatment 8 upvotes 1 month ago

Grapefruit juice doesn't significantly affect finasteride or dutasteride. Drinking topical minoxidil is risky; saw palmetto is less effective than finasteride or dutasteride for hair loss.

community Eliminating scalp itch leads to regrowth (and my RU58841 progress)

in Research/Science 64 upvotes 1 year ago

User experienced hair regrowth after eliminating scalp itch with RU58841. Others discussed itch and hair loss connection, and effectiveness of combining RU58841 with 5AR inhibitors.

community Could low blood flow to the head cause an increased rate of thinning?

in Chat 27 upvotes 3 years ago

The user started using finasteride, minoxidil, and biotin for male pattern baldness (MPB) and is experiencing rapid thinning. They are questioning if low blood flow to the head could be contributing to their hair loss.

community FINASTRIDE and switch to DUTASTRIDE, my experience

in Progress Pictures 134 upvotes 2 months ago

The user shared their experience with Finasteride and Dutasteride for hair loss. They initially had success with Finasteride but switched to Dutasteride after experiencing shedding, which continued, and are now considering a hair transplant.

community 57% increased chance of pattern hair loss independently associated with the consumption of sugary beverages in men (p<0.001) Pt 2

in Research/Science 481 upvotes 3 months ago

Sugary beverages increase the risk of pattern hair loss in men by 57%. Treatments discussed include Minoxidil, finasteride, and RU58841.

community Topical finasteride now the safest possible path?

in Finasteride/Dutasteride 50 upvotes 3 months ago

Topical finasteride is considered a safer option for hair regrowth with fewer systemic side effects compared to oral finasteride. Some users report similar efficacy and side effects between topical and oral treatments, while others prefer topical due to reduced systemic exposure.

community Oral minoxidil is not good for your health, let’s use research chemicals bought from AliExpress

in Satire 551 upvotes 1 year ago

. This conversation discussed the efficacy of Minoxidil and Finasteride as treatments for hair loss, with a focus on the potential side effects of taking Oral Minoxidil. Some users shared their experiences with both treatments and there was debate over whether they were safe or not.

community Mark Normand talks about finasteride experience

in Finasteride/Dutasteride 826 upvotes 1 year ago

The conversation is about hair loss and the use of finasteride as a treatment. Some users share their positive experiences with finasteride, while others mention side effects they have experienced.

community Why is dht bad for scalp hair but good for hair on the rest of body?

in Satire 109 upvotes 1 year ago

The conversation discusses why DHT (dihydrotestosterone) negatively affects scalp hair but promotes growth elsewhere on the body. Various opinions include genetic predispositions, differences in hair follicle reactions to DHT, and the potential role of Omega-3 in reducing inflammation and promoting hair health.

community I have been gaining weight easily since taking Dutasteride.

in Finasteride/Dutasteride 19 upvotes 1 year ago

A user's experience of gaining weight while taking Dutasteride, and suggestions on how to continue using it without the negative side effects, such as exercising and tracking calories or switching to Finasteride.

community DIY Dutasteride Mesotherapy....THE ULTIMATE EXPERIMENT WITH RESULTS!

in Finasteride/Dutasteride 155 upvotes 3 years ago

User tried DIY Dutasteride Mesotherapy for hair loss due to unsatisfactory Finasteride results. Used mesotherapy injection gun and liquid dutasteride for better results and fewer side effects.

community 1 Year Progress On 0.5mg Finasteride + 5mg Minoxidil

in Progress Pictures 1314 upvotes 6 months ago

A user shared a 1-year progress on hair loss treatment using 0.5mg of oral finasteride and 5mg of oral minoxidil, showing significant hair regrowth from almost bald to much thicker hair. Other users discussed their own experiences with these treatments, with some preferring topical applications to avoid side effects.

community 12 mo 1 ml daily Min/Dermaroller 1mm-1.5mm update + AGA progression theory and specific order of treatment

in Microneedling 15 upvotes 3 years ago

A user shared their year-long hair loss treatment using minoxidil, microneedling, and scalp massages, reporting moderate hair growth and stabilization. They suggest starting early with less harmful methods and consider adding finasteride or dutasteride if needed.

community 14 months into fin + min and my hair is way worse than before

in Chat 23 upvotes 3 weeks ago

The user experienced worsening hair loss despite using finasteride, minoxidil, and microneedling. Suggestions included reducing microneedling frequency, switching to oral minoxidil, adding tretinoin, and considering dutasteride.

community Gyno & testoterone level

in Finasteride 282 upvotes 4 months ago

Switching from finasteride to dutasteride and back to finasteride led to gynecomastia and fatigue, likely due to hormonal imbalances. Suggested treatments include Tamoxifen, Raloxifene, or low-dose Anastrozole, with a recommendation to test testosterone and estradiol levels.

community Feeling really down and hair loss is slowly destroying me

in Chat 86 upvotes 4 years ago

The conversation is about a person struggling with aggressive hair loss and feeling depressed, who has tried finasteride but is experiencing sexual side effects. Others suggest various treatments like reducing finasteride dosage, trying minoxidil, dermarolling, addressing health and hormonal issues, and accepting baldness.

community What treatment helps diffuse hair thinning from insulin resistance?

in Treatment 1 upvotes 1 year ago

The individual is experiencing hair loss due to insulin resistance (IR) and is seeking advice. They are currently using a keto diet, supplements, exercise, and plan to add metformin to their regimen.

community ‘Long term use of fin/dut may be associated with health risks including fatty liver disease, insulin resistance, type 2 diabetes, dry eye disease and potential kidney disease.’

in Research/Science 22 upvotes 3 months ago

Long-term use of finasteride and dutasteride may be linked to health risks like fatty liver disease, insulin resistance, type 2 diabetes, dry eye disease, and potential kidney disease. Some users believe the risks are low and the medications are generally safe.

community Hair started thinning and found out i have high cortisol and thyroid issues

in Treatment 8 upvotes 5 months ago

User experienced hair thinning due to high cortisol and thyroid issues, along with insulin resistance. They are taking magnesium, zinc, vitamin D, calcium, and selenium as supplements.

community Study: Dutasteride Mesotherapy Accelerates Hair Loss in Female Patients with Metabolic Syndrome

in Finasteride/Dutasteride 15 upvotes 7 months ago

Dutasteride mesotherapy in women with metabolic syndrome accelerated hair loss after initial regrowth, while women without metabolic syndrome saw continuous regrowth. The user with mild insulin resistance is hesitant to try topical dutasteride and seeks experiences from others with insulin resistance.

community Akkermansia improves testosterone-induced hair growth inhibition.

in Research/Science 3 upvotes 11 months ago

Akkermansia bacteria can improve hair growth inhibited by testosterone, and metformin may increase Akkermansia, which could help with hair loss related to aging, insulin resistance, and inflammation.

community Carnitine Tartrate + Potassium chloride + Niacin

7 upvotes 9 years ago

The post discusses using Carnitine Tartrate, Potassium Chloride, and Niacin to reduce hair shedding, with the user experiencing significant improvement. The user also suggests considering a ketogenic/paleo diet for those with insulin resistance-related hair loss.

community IGFBP‐rP1 is a potential therapeutic target in androgenic alopecia

in Research/Science 13 upvotes 1 week ago

IGFBP‐rP1 shows potential for treating androgenic alopecia by influencing hair cycle transitions. Increasing IGF-1 levels may have similar effects to Minoxidil and 5-AR inhibitors in reducing hair loss.

community Are carbohydrates needed for hair growth

in Research/Science 26 upvotes 3 months ago

A 47-year-old male experienced significant hair loss after losing 37 kg in 6 months on a low-carb diet and started taking biotin, zinc, iron, selenium, and spectral dcn-n. Replies suggest that while carbs are not directly needed for hair growth, they help regulate hormones and nutrient absorption, and rapid weight loss can also contribute to hair loss.

community Bloodwork after 8 months on finasteride, is this normal?

in Update 28 upvotes 6 months ago

A user on finasteride for 8 months shared bloodwork results showing increased testosterone and estradiol levels, with concerns about high LH. Responses advised monitoring for symptoms but noted levels are within reference ranges.

community Anyone have experience with natural DHT blockers?

in Finasteride/Dutasteride 7 upvotes 11 months ago

The conversation is about using natural DHT blockers like pumpkin seed oil and saw palmetto extract for hair loss. The user has been using minoxidil, derma rolling, vitamin D, and biotin but is considering finasteride next.

community I don't know what happened with me sudden hair loss from 6 months i use dut ,min , vitamin all things but no response

in Progress Pictures 18 upvotes 1 year ago

The person is experiencing sudden hair loss for six months and treatments like dutasteride, minoxidil, and vitamins are not working. Another person suggests the hair loss might not be androgenetic alopecia but could be telogen effluvium or an inflammatory condition.

community Finasteride and Metformin together?

in Finasteride/Dutasteride 1 upvotes 1 year ago

The conversation is about whether it's safe to take Metformin for weight loss and Finasteride together, with the concern that Finasteride is not commonly used for hair loss treatment in the user's location, and their doctor is not knowledgeable about it.