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GlossaryInsulin Resistance

condition where cells don't respond well to insulin

Insulin Resistance (IR) is a condition where the body's cells become less responsive to the hormone insulin, which is crucial for regulating blood sugar levels. As a result, the pancreas produces more insulin to compensate, leading to higher insulin levels in the blood and potentially progressing to type 2 diabetes. This condition is often associated with obesity, physical inactivity, and genetic factors.

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community What treatment helps diffuse hair thinning from insulin resistance?

in Treatment 1 upvotes 1 year ago

The individual is experiencing hair loss due to insulin resistance (IR) and is seeking advice. They are currently using a keto diet, supplements, exercise, and plan to add metformin to their regimen.

community ‘Long term use of fin/dut may be associated with health risks including fatty liver disease, insulin resistance, type 2 diabetes, dry eye disease and potential kidney disease.’

in Research/Science 22 upvotes 5 months ago

Long-term use of finasteride and dutasteride may be linked to health risks like fatty liver disease, insulin resistance, type 2 diabetes, dry eye disease, and potential kidney disease. Some users believe the risks are low and the medications are generally safe.

community Hair started thinning and found out i have high cortisol and thyroid issues

in Treatment 8 upvotes 6 months ago

User experienced hair thinning due to high cortisol and thyroid issues, along with insulin resistance. They are taking magnesium, zinc, vitamin D, calcium, and selenium as supplements.

community Study: Dutasteride Mesotherapy Accelerates Hair Loss in Female Patients with Metabolic Syndrome

in Finasteride/Dutasteride 15 upvotes 9 months ago

Dutasteride mesotherapy in women with metabolic syndrome accelerated hair loss after initial regrowth, while women without metabolic syndrome saw continuous regrowth. The user with mild insulin resistance is hesitant to try topical dutasteride and seeks experiences from others with insulin resistance.

community Akkermansia improves testosterone-induced hair growth inhibition.

in Research/Science 3 upvotes 1 year ago

Akkermansia bacteria can improve hair growth inhibited by testosterone, and metformin may increase Akkermansia, which could help with hair loss related to aging, insulin resistance, and inflammation.

community Carnitine Tartrate + Potassium chloride + Niacin

7 upvotes 10 years ago

The post discusses using Carnitine Tartrate, Potassium Chloride, and Niacin to reduce hair shedding, with the user experiencing significant improvement. The user also suggests considering a ketogenic/paleo diet for those with insulin resistance-related hair loss.

community Bloodwork after 8 months on finasteride, is this normal?

in Update 27 upvotes 8 months ago

A user on finasteride for 8 months shared bloodwork results showing increased testosterone and estradiol levels, with concerns about high LH. Responses advised monitoring for symptoms but noted levels are within reference ranges.

community Anyone have experience with natural DHT blockers?

in Finasteride/Dutasteride 7 upvotes 1 year ago

The conversation is about using natural DHT blockers like pumpkin seed oil and saw palmetto extract for hair loss. The user has been using minoxidil, derma rolling, vitamin D, and biotin but is considering finasteride next.

community I don't know what happened with me sudden hair loss from 6 months i use dut ,min , vitamin all things but no response

in Progress Pictures 18 upvotes 1 year ago

The person is experiencing sudden hair loss for six months and treatments like dutasteride, minoxidil, and vitamins are not working. Another person suggests the hair loss might not be androgenetic alopecia but could be telogen effluvium or an inflammatory condition.

community Proposed new pathogenesis model for androgenetic alopecia (AGA)

in Research/Science 8 upvotes 1 year ago

The conversation discusses a new model for understanding androgenetic alopecia (AGA), linking it to dietary and lifestyle factors similar to PCOS, and highlighting the role of DHT, vascular damage, and inflammation. Treatments mentioned include Minoxidil, finasteride, and RU58841.

community Can diet play a big role in preventing loss/ speeding up growth? Are there foods that slow down hair growth?

in Chat 3 upvotes 2 years ago

User experienced hair loss on the top of the head for 2 years, noticed improvement after adding a smoothie with various fruits, vegetables, and seeds to their diet. They observed increased hair growth after 2 weeks of this dietary change.

community AA and Hirsutism but T levels are normal

in Female 8 upvotes 3 years ago

27-year-old female experiences aggressive hair thinning and hirsutism despite normal testosterone levels. Spironolactone and 2% minoxidil were ineffective; high DHEA sulfate levels may be the cause.

community COVID made me lose my hair. My friends helped me get it back (vertex balding treatment success story)

in Minoxidil 8 upvotes 4 years ago

A 34-year-old man experienced hair loss during the COVID-19 pandemic and successfully treated it using minoxidil, reducing shampoo use, and taking fenugreek. He saw significant improvement within a few months and no longer appears bald.

community Having androgen receptor density and sensitivity at wrong f*ing place

in Satire 7 upvotes 2 months ago

The conversation discusses hair loss treatments, focusing on the use of topical minoxidil, microneedling, finasteride, and dutasteride, while debating the role of testosterone and DHT in hair loss. It also touches on the potential liver health impacts of these treatments and the genetic sensitivity of hair follicles to androgens.

community My first 8 months and prgress so far, min + fin.

in Progress Pictures 3 upvotes 2 months ago

The user started experiencing hair loss at 26 and began treatment with topical minoxidil and oral finasteride. After 8 months, they noticed hair regrowth, especially baby hairs, and remain hopeful for further improvement.

community Are carbohydrates needed for hair growth

in Research/Science 26 upvotes 4 months ago

A 47-year-old male experienced significant hair loss after losing 37 kg in 6 months on a low-carb diet and started taking biotin, zinc, iron, selenium, and spectral dcn-n. Replies suggest that while carbs are not directly needed for hair growth, they help regulate hormones and nutrient absorption, and rapid weight loss can also contribute to hair loss.

community Do we have to be junkies? That's funny

in Research/Science 13 upvotes 5 months ago

The conversation discusses using finasteride, dutasteride, minoxidil, cialis, and metformin to protect hair and health. Some users caution against self-prescribing these drugs due to potential risks and complications.

community How much would a high dose dutasteride scalp dht inhibition be?

in Finasteride/Dutasteride 10 upvotes 8 months ago

The conversation discusses the potential for high doses of dutasteride to completely inhibit scalp DHT and speculates whether this could cure baldness when combined with a topical antiandrogen. Specific dosages mentioned are 0.5 mg reducing scalp DHT by 55% and 2.5 mg by about 79%.

community Update to fin 0.25 mg, 4x/week

in Progress Pictures 64 upvotes 1 year ago

User reported initial hair regrowth with 0.25 mg finasteride taken four times a week, experiencing a second shedding phase, and no side effects. They also mentioned using RU58841 without success and plan to stop after a year.

community I'm a 32 year old male with Norwood 3 with heavy diffuse thinning, I'm about to start my hair loss regiment. It goes as follows

in Update 22 upvotes 1 year ago

A 32-year-old male with Norwood 3 and heavy diffuse thinning is starting a hair loss treatment including RU58841, Minoxidil, finasteride, derma rolling, vitamins, and possibly MK677, while cutting out most sugars from his diet. He plans to share progress photos and updates on his test levels.

community Dutasteride broked my liver (maybe)

in Finasteride/Dutasteride 8 upvotes 2 years ago

A user shared their experience with high cholesterol, glucose, and potential metabolic syndrome after using Finasteride and Dutasteride for hair loss. They plan to improve their health with diet and exercise before considering medication.

community POST ACCUTANE HAIR LOSS- Please help and leave your experiences and suggestions

in Female 10 upvotes 3 years ago

A user named Medical_Opinion8120, a 23-year-old female, is experiencing hair loss potentially due to a past accutane course. She has tried minoxidil without success and is currently taking iron and zinc supplements.

community I have successfully stopped my hormone-induced hair loss ( caused by PCOS,) for 2 years now but I can't seem to be able to regrow the lost hair. Has anyone tried Platelet-Rich Plasma Therapy (PRP)?

in Female 6 upvotes 3 years ago

GentleIris stopped hormone-induced hair loss with diet changes but couldn't regrow lost hair. A reply suggested microneedling instead of Platelet-Rich Plasma Therapy (PRP) for hair regrowth.

community 27F with questions

4 upvotes 6 years ago

A 27-year-old woman is seeking advice on hair loss treatments, considering options like Spiro, Viviscal tablets, Rogaine, dermarolling, Nizoral shampoo, saw palmetto, castor oil, jojoba oil, and spearmint tea. She has a history of hair loss since childhood, has tried various treatments, and is looking for effective solutions before accepting her condition.

community 26/F - Lots of stuff going on - Pics inside.

7 upvotes 9 years ago

A 26 year old female with PCOS who has been dealing with hair loss for several years, despite managing her hormones and taking vitamins. She has tried various treatments such as Nizoral, Minoxidil, Pyrithione zinc, coal tar and salicylic acid to no avail. The user is looking for advice on what else they can do to stop their hair loss.

community Interesting article links major MPB theories to western diet (and life-style)

in Research/Science 53 upvotes 1 month ago

Poor diet and lifestyle contribute to male pattern baldness. Treatments like Minoxidil, dietary changes, and lifestyle adjustments may help slow hair loss.

community Efficacy of different dutasteride doses vs finasteride

in Research/Science 123 upvotes 1 year ago

Dutasteride doses matter for hair loss treatment and are more effective than finasteride. RU58841 is suggested for better gains, but side effect profiles should be considered.

community Horrible news, Stemson Therapeutics has shut down

in Technology 193 upvotes 1 week ago

Stemson Therapeutics has shut down, disappointing those seeking a hair loss cure. Current treatments like minoxidil, finasteride, and dutasteride are discussed, with some users experiencing side effects and exploring alternatives like PP405.

community Ultimate Stack without nuking your gender (you'll go broke)

in Treatment 81 upvotes 4 weeks ago

A hair loss treatment plan includes finasteride, dutasteride, RU58841, pyrilutamide, minoxidil, and microneedling to inhibit DHT and promote hair growth. It also recommends supplements like Reishi and Lion’s Mane mushrooms, and a shampoo with ketoconazole, caffeine, and melatonin.

community Increased Coffee intake resulted in massive shed

in Finasteride/Dutasteride 18 upvotes 1 month ago

Increased coffee intake might be linked to hair shedding, but the cause is unclear. The user is on finasteride and has increased water intake, possibly affecting electrolyte balance.