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      community Bile Acid-Mediated DHT Dysregulation Hypothesis

      in Research/Science  13 upvotes 2 weeks ago
      Elevated bile acids can inhibit the enzyme AKR1C2, leading to increased DHT levels, which may accelerate hair loss in those predisposed to androgenetic alopecia. Treatments mentioned include topical minoxidil and finasteride.

      community Verteporfin and Microneedling

      in Treatments 5 months ago
      Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.

      community 23M losing ground very after seeing improvements

      in Progress Pictures  23 upvotes 6 months ago
      A 23-year-old male was using 0.5 mg of dutasteride daily, 10% minoxidil twice daily for 4-5 months then once daily, and vitamin D for a month for hair loss treatment but saw a decline in results. It's suggested that the decline may be due to reducing minoxidil application to once a day and a doctor's visit is recommended for further advice.

      community Opinions on Scalp fibrosis and DHT?

      in Research/Science  9 upvotes 2 years ago
      The conversation discusses the theory that scalp fibrosis contributes to male pattern baldness (MPB) by increasing DHT concentration, and mentions treatments like Minoxidil. The user seeks opinions on the theory and the effectiveness of scalp massages.

      community 27F with questions

       4 upvotes 6 years ago
      A 27-year-old woman is seeking advice on hair loss treatments, considering options like Spiro, Viviscal tablets, Rogaine, dermarolling, Nizoral shampoo, saw palmetto, castor oil, jojoba oil, and spearmint tea. She has a history of hair loss since childhood, has tried various treatments, and is looking for effective solutions before accepting her condition.

      community Creatine made all my high DHT symptoms return

      in Research/Science  78 upvotes 3 weeks ago
      Creatine may increase DHT levels, potentially causing symptoms like acne, oily hair, and hair shedding. Users report mixed experiences, with some avoiding creatine due to hair loss concerns and others seeing no impact.

      community Finasteride + topical melatonin + rosemary oil for regrowth

      in Treatment  1 upvotes 5 months ago
      The user has been using finasteride for 4 months with positive results, including thicker and darker hair. They are seeking advice on maximizing hair growth without minoxidil, using a routine that includes finasteride, rosemary oil, argan oil, topical melatonin, specialized shampoos, and vitamins.

      community Best shampoo and conditioner for hair loss

      in Product  6 upvotes 5 months ago
      The user is using minoxidil, finasteride, Nizoral 2%, and microneedling for hair loss but finds Nizoral drying. They seek affordable shampoo and conditioner recommendations, with one reply suggesting baby shampoo for non-Nizoral days.

      community Rare Non responder to Finasteride, Dutasteride, and oral minoxidil

      in Minoxidil  78 upvotes 8 months ago
      A user did not respond to finasteride, dutasteride, and oral minoxidil for hair loss after four years of treatment and is considering scalp micropigmentation (SMP). Other users suggest the hair loss pattern may indicate alopecia areata and recommend seeing a dermatologist.

      community High Estrogen causing hair loss?

      in Treatment  15 upvotes 1 year ago
      A 24-year-old male using topical finasteride for hair loss is experiencing thinning despite treatment and has high estrogen levels. He is seeking advice on whether high estrogen could be causing hair loss and how others with high estrogen levels have addressed it.

      community shampoo nizoral 1% information

      in Ketoconazole  3 upvotes 1 year ago
      User has itching, dandruff, and scalp issues, considering Nizoral 1% shampoo for treatment. Nizoral's effectiveness for hair loss is uncertain due to limited research, short contact time, and concentration differences.

      community I will have it cured by morning

      in Research/Science  370 upvotes 1 year ago
      Researching the cause of hair loss and treating it by preventing DHT in the scalp with medication such as finasteride or dutasteride, estrogen, minoxidil, dermarolling, and possible topical antiandrogens.

      community I am a dermatologist with a clinical interest in alopecia. AMA

      in Will treatment work for me? 2 years ago
      In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

      community Why I deleted my YouTube channel Part I

      in Update  118 upvotes 3 years ago
      A YouTuber named Kevin, also known as Rider_Of_Roach, who deleted his YouTube channel due to personal attacks and controversy surrounding his views on hair loss treatments. He advocated for FDA-approved treatments like finasteride and minoxidil but faced backlash from those who disagreed with him. The conversation also discusses his past trolling behavior and a lawsuit he filed against a website that published false information about him. Despite some disagreements, many viewers appreciated his research-based content and hope to see him return in the future.

      community My hair loss theory and what I did to stop my hair loss. 6 years of stabilization.

      in Treatment  7 upvotes 4 years ago
      A user shared their personal theory on hair loss, suggesting it's caused by reduced blood flow and scalp calcification rather than DHT, and claimed to have stopped their hair loss by massaging the scalp, using acid peels, and applying oils and copper peptides. They have not noticed further hair loss for six years since starting this routine.

      community Using essential oils as well as minoxidil?

      in Minoxidil  6 upvotes 6 years ago
      The conversation is about using a blend of coconut oil, peppermint oil, and rosemary oil with minoxidil for hair loss, and whether it's safe to apply this blend after microneedling.

      community Efficacy of Dut at 0.5mg VS 1mg VS 2.5mg

      in Finasteride/Dutasteride  44 upvotes 3 days ago
      Higher doses of dutasteride, such as 2.5mg, are more effective at reducing scalp DHT than 0.5mg, but are costly and inconvenient. A 1mg dose is considered a more affordable and practical option, though its efficacy is uncertain.

      community Finally Scalp Folliculitis-Free after 2 Decades of Suffering

      in Treatment  59 upvotes 2 weeks ago
      A 37-year-old male resolved scalp folliculitis by adopting a low-histamine diet and taking Vitamin A, Zinc, and Fish Oil, leading to better skin health and thicker hair. He warns about the potential toxicity of excessive Vitamin A intake.

      community 1ish year on fin and no improvement

      in Is this regrowth?  86 upvotes 1 month ago
      The user has been using finasteride for over a year without improvement and recently started oral minoxidil. Suggestions include trying dutasteride and continuing minoxidil for potential regrowth.

      community Hairloss Treatment - General health and efficacy-conscious stack overview

      in Treatment 1 month ago
      The conversation discusses managing hair loss and seborrheic dermatitis with treatments like minoxidil, finasteride, and saw palmetto, emphasizing the importance of scalp health and DHT reduction. The user shares personal experiences and suggests a balanced approach, combining topical treatments and lifestyle changes for effective hair regrowth.