Finasteride can reduce semen volume due to prostate shrinkage but doesn't affect fertility. To increase semen volume, consider zinc, lecithin, and reducing finasteride dosage.
The conversation discusses using 0.5mg Dutasteride once a week for hair loss, with suggestions to increase frequency for better results. The user plans to reassess the need for a hair transplant in six months and is concerned about potential side effects like gynecomastia.
Clascoterone 5% solution showed a 539% improvement in hair count compared to placebo, but the actual increase in hair growth is minimal. Users express skepticism about the effectiveness of hair loss treatments.
Breezula shows promising hair growth results, with up to 539% increase in hair count compared to placebo, and regulatory submissions are planned in the US and EU. Users are cautiously optimistic, noting the potential for Breezula to replace finasteride by targeting DHT without systemic effects.
PP405 trials have completed phase 2a, showing promising results with a 31% stat for hair density increase, and are moving directly to phase 3. Detailed results will be presented at a medical conference in 2026.
PP405 shows potential for hair growth, with 31% of advanced balding men experiencing over 20% increase in hair density in 8 weeks. However, skepticism persists due to selective data presentation and lack of long-term results, with comparisons to treatments like minoxidil and finasteride.
The discussion focuses on hair loss treatments, with suggestions to increase oral Dutasteride to 1 mg or more, as topical Dutasteride is less effective. Other treatments mentioned include RU58841, Minoxidil, and dermastamping, with some users recommending injectable mesotherapy and topical Finasteride.
Creatine is believed by some users to cause hair shedding, though a study found no increase in DHT or testosterone levels. Many users shared personal experiences of hair loss after using creatine, while others noted no change, suggesting individual variability.
An 18-year-old started taking 1mg of finasteride daily to address receding temples and is concerned about whether they will need to increase the dose or switch to dutasteride in the future. Users discuss that finasteride can slow hair loss for many years, but it is not a permanent solution, and individual responses vary.
The user experienced beard loss from finasteride and RU58841 while managing hair loss. They plan to increase RU58841 dose, use a dermaroller, and consider oral minoxidil to improve hair growth without affecting their beard.
JW0061 shows superior hair growth results compared to existing treatments, with significant increases in hair follicles. The Wnt/β-catenin pathway is crucial for hair growth, and JW0061 activates this pathway effectively.
The conversation discusses the user's experience with oral minoxidil for hair loss and a possible increase in facial wrinkles, leading to a plan to ask for a tretinoin prescription. Specific treatments mentioned are oral minoxidil and the intention to use tretinoin.
The conversation discusses concerns about using Ashwagandha with Dutasteride for hair loss, as Ashwagandha may increase testosterone and potentially affect DHT levels. Users generally agree that the increase in DHT is minimal and unlikely to impact the effectiveness of Dutasteride significantly.
Akkermansia bacteria can improve hair growth inhibited by testosterone, and metformin may increase Akkermansia, which could help with hair loss related to aging, insulin resistance, and inflammation.
The conversation discusses whether drinking green tea affects hair loss, with one user concerned it might increase DHT levels. The user is already using finasteride and wants to ensure green tea doesn't hinder progress.
The conversation discusses whether ashwagandha affects hair loss, with one user noting no increase in hair loss while using it and another suggesting it may help slow hair loss by reducing stress. The original poster is using finasteride daily and is concerned about ashwagandha's impact on hair loss.
Melatonin's effect on aromatase expression is unclear, with studies showing both increases and decreases. Hormonal impacts are complex and inconsistent, similar to changing health advice on other substances.
A dermatologist recommended a new supplement containing annurca apple, which reportedly doubles hair density and increases keratin after 60 days, to be used with finasteride. Some users are skeptical, considering it potentially ineffective or a marketing ploy, while others are open to trying it if it proves effective and affordable.
The user started a hair loss treatment with finasteride and minoxidil, then switched to dutasteride and minoxidil, experiencing increased body hair and reduced alcohol tolerance. They plan to get a hair transplant in 12 months and have received compliments on their eyelashes.
The conversation discusses using both topical and oral minoxidil for hair loss. The user is interested in others' experiences with this combination, including any benefits like increased density or better regrowth.
The user shared progress photos showing hair improvement after using topical finasteride and Minoxidil for six months. The treatment was prescribed by a dermatologist, and the user noted increased hair density and a lower hairline.
A 20-year-old experienced significant hair recovery in three months using a combination of topical and oral minoxidil, along with finasteride and multivitamins. Initial side effects included a perceived increase in breast size and reduced libido, but these resolved, and the user is pleased with the progress.
The user is using Minoxidil and finasteride for hair loss and is concerned about the lack of visible progress after two months, despite some users noting increased hair density. Increased shedding is considered normal and a sign of effectiveness.
A 20-year-old male is experiencing hairline and temple hair loss and has been using finasteride, minoxidil, tretinoin, and ketoconazole with positive results. He increased his finasteride dose and is considering switching to oral minoxidil, though some advise against it.
A 26-year-old male has been using oral and topical minoxidil and finasteride for hair loss over three months, experiencing increased body hair as a side effect but no significant negative effects. He plans to continue treatment consistently for a year before considering a transplant, and users suggest standardizing photo comparisons to accurately track progress.
The conversation discusses elevated hormone levels after using Finasteride for 2 months and Dutasteride for 2 weeks for hair loss. Users suggest that increased testosterone and estradiol levels are expected due to DHT inhibition, and it's not a concern unless symptoms occur.
The conversation discusses hair loss treatment progress using 1 mg finasteride and 2 mg oral minoxidil daily. The user reports increased body hair as a side effect.
The user experienced significant hair growth after adding ostrich oil and weekly microneedling to their existing treatment of topical dutasteride and minoxidil. They believe the combination of ostrich oil and microneedling contributed to the results, although some users suggest the increased microneedling frequency might be the main factor.
The user shared progress pictures showing significant hair regrowth after using finasteride, dutasteride, and minoxidil for over a year. They transitioned from finasteride to dutasteride gradually and noticed hairline regrowth and increased density, with some hair responding better to treatment than others.