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GlossaryInterleukin-36 (IL-36)

group of cytokines involved in immune system signaling and inflammation

Interleukin-36 (IL-36) is a group of cytokines, which are small proteins important for cell signaling in the immune system. These cytokines play a crucial role in inflammatory responses and are involved in the pathogenesis of various autoimmune and inflammatory diseases, such as psoriasis. IL-36 includes three agonists (IL-36α, IL-36β, and IL-36γ) and an antagonist (IL-36Ra), which together help regulate the body's immune response.

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community What is the real impact of dutasteride on neurosteroids? A little review of 2 scientific datas

in Research/Science 21 upvotes 4 months ago

Dutasteride at 0.5 mg/day does not significantly alter allopregnanolone levels, but higher doses (2.5 mg/day) do. Dutasteride may also have anti-neuroinflammatory effects, but the impact on neurosteroids is still debated.

community Stop supporting Keeps and Roman, they’re price gouging you

in Finasteride/Dutasteride 360 upvotes 1 year ago

The post discusses the high cost of hair loss treatments from companies like Keeps and Roman, and suggests cheaper alternatives like GoodRx. Users share their experiences with different providers, costs, and methods of obtaining finasteride, a common hair loss treatment.

community 12 mo update: oral (dut, min), topical (RU, min), microneedling

in Progress Pictures 349 upvotes 1 year ago

A user's 12 month update on treatment for hair loss, which include oral dutasteride and minoxidil, topical RU88541 and minoxidil, microneedling with hyaluronic acid and FinDuta, experiencing no side effects, positive results and inspiring other users.

community dutasteride 9 months, nonstop hair loss

in Finasteride/Dutasteride 31 upvotes 2 years ago

Experiencing continual nonstop hair loss despite using dutasteride for 9 months, and the possible causes behind it being discussed such as nutritional deficiencies, elevated cortisol, vitamin D deficiency or other problems. Other solutions such as minoxidil and finasteride have been suggested.

community I am having Success with RU58841 and 1mm Derma Roller

in Microneedling 19 upvotes 2 years ago

A user reported success with RU58841 and a 1mm derma roller for hair regrowth, noting significant improvement in hair density and reduced scalp visibility. They also mentioned using minoxidil and black castor oil in the past, with mixed results.

community I am finally giving up on my hair

in Shaved/buzzed 57 upvotes 1 year ago

User tried Minoxidil and Finasteride for hair loss with no success and considers giving up. Others suggest continuing treatment, trying hair transplant, or embracing baldness.

community 1 year after my Hair Transplant

in Progress Pictures 161 upvotes 1 year ago

Hair transplant after 1 year shows great results. Treatment done in Turkey, patient from Pakistan living in Germany.

community Fin- 4.5 months, Min-2.5 months, still long way to go

in Progress Pictures 64 upvotes 9 months ago

The user has been treating hair loss with 1mg oral finasteride daily, 1mg topical minoxidil twice daily, and microneedling twice a week. They report improved hair quality and density but are still experiencing shedding.

community Shed 2 years into finasteride and minoxidil

in Minoxidil 8 upvotes 3 months ago

A user has been on finasteride for 1.5 years and minoxidil for 2 years, experiencing worsening hair shedding, losing 300+ hairs per wash. They are concerned if this indicates the medicine isn't working and are seeking others' experiences.

community Does anyone manage to keep the estradiol under control while on fin ? I'm talking in the normal range

in Chat 3 upvotes 4 months ago

Managing estradiol levels while using finasteride. Treatments discussed include Minoxidil, finasteride, and RU58841.

community NMN Promotes Cell Proliferation and Hair Growth by Reducing Oxidative Stress

in Research/Science 14 upvotes 5 months ago

NMN shows promise in promoting hair growth by reducing oxidative stress and weakening androgens. It may be a beneficial addition to hair loss treatments like Minoxidil and Finasteride.

community 1 year regime. Stabilizing a bit

in Progress Pictures 81 upvotes 5 months ago

A 30-year-old man using minoxidil for hair loss is seeing stabilization but no significant regrowth. He is hesitant about finasteride due to potential side effects and is seeking alternative methods to promote hair growth.

community 7 months on just topical finasteride (caretopic)

in Progress Pictures 52 upvotes 5 months ago

A user shared their 7-month progress using only topical finasteride for hair loss. They recently started a new, non-FDA treatment and will evaluate its effectiveness in 6 months.

community Recent recipient of a 5000 graft hair transplant in Istanbul….

in Transplants 245 upvotes 8 months ago

A user underwent a 5000 graft hair transplant in Istanbul, which included 900 beard grafts, after previously using finasteride with limited success. The procedure cost £4500, including transport and aftercare in both Istanbul and the UK.

community Good luck on everybody on the fight against hair loss!

in Update 325 upvotes 2 years ago

Acknowledging the struggle of hair loss, discussing treatments like finasteride, minoxidil and RU58841, and providing support to those dealing with it.

community 50 years old 4.5 months on Fin

in Finasteride/Dutasteride 28 upvotes 3 years ago

A 50-year-old user shared their positive experience with hair regrowth using finasteride, minoxidil, biotin, pumpkin seed oil, derma rolling, biotin shampoo, and Nizoral. They reported significant improvement in hair density and regrowth, especially in the crown and mid-scalp areas, with no side effects.

community Will rubbing olive oil on my thinning spots when I get the dht itch slow down/maybe stop balding?

in Research/Science 3 years ago

Olive oil may temporarily relieve DHT itch but won't stop balding. Finasteride and Minoxidil are recommended for hair loss treatment.

community Finasteride, Nizoral and dermarolling 2 months update

in Finasteride/Dutasteride 207 upvotes 4 years ago

Hair loss treatments, specifically the use of Finasteride, Nizoral, and dermarolling; potential results from these treatments are discussed, along with potential side effects.

community Dutasteride 4.5 months really struggling what should I do

in Finasteride/Dutasteride 18 upvotes 6 days ago

The user has been on dutasteride for 4.5 months after switching from finasteride due to hair thinning, and is experiencing significant hair loss despite also using minoxidil and microneedling. Many responses suggest that dutasteride takes time to show results, often requiring patience for up to a year or more, and recommend not stopping finasteride abruptly to avoid shedding.

community After Finasteride now it's the turn to get Dutasteride easily in Italy!

in Finasteride/Dutasteride 91 upvotes 1 week ago

An individual in Italy used a fake prescription to obtain Dutasteride cheaply, suggesting others do the same to avoid high costs. They discuss the effectiveness and side effects of Dutasteride compared to Finasteride for hair loss, with some users considering switching due to better tolerance.

community Does this mean it's finally working

in Finasteride/Dutasteride 2 upvotes 3 months ago

The user started using topical minoxidil in June 2023 and switched to a new finasteride preparation and vitamin D supplements a month ago. They noticed reduced hair shedding recently and are hopeful for regrowth.

community Breaking hair loss news! GT20029 is a resounding success!

in Product 138 upvotes 7 months ago

GT20029, a new hair loss treatment, shows promising results but only a slight improvement over placebo. People are cautiously optimistic, discussing its potential and combining it with existing treatments like Minoxidil and Finasteride.

community do any supplements actually work?

in Female 6 upvotes 8 months ago

A user asked if collagen or hair growth supplements made their hair thicker. Another user suggested that Vitamin D might help if deficient.

community 1 year topical fin/min coupled with frontal HT

in Progress Pictures 192 upvotes 10 months ago

The user experienced significant hair improvement after one year using topical finasteride and minoxidil, combined with a hair transplant at the front. They switched from oral to topical finasteride due to side effects and are satisfied with the results, especially at the temples.

community Anyone else just waiting until the real pyrilutamide and then GT20029?

in Chat 1 year ago

The user is hesitant to use finasteride due to potential hormonal side effects and is waiting for the release of pyrilutamide, a new hair loss treatment. Other users suggest trying finasteride, warning about potential regret if hair loss progresses in the meantime.

community (25Y) Oral minoxidil 10 months Oral fin 7 months & other things

in Progress Pictures 52 upvotes 1 year ago

A person treated their diffuse alopecia with oral minoxidil (10mg daily), oral finasteride (reduced to 0.25mg daily due to side effects), castor oil, vitamins, and ashwagandha, and plans a hair transplant in Turkey. They stopped using topical minoxidil, have seen improved hair density, but are still experiencing hair loss.

community We really out here with a subscription service for our hair...

in Satire 324 upvotes 1 year ago

Hair loss discussion mentions using Minoxidil, Finasteride, and RU58841. Users compare subscription services for hair treatments to other daily necessities and discuss cheaper alternatives.

community I will have it cured by morning

in Research/Science 370 upvotes 1 year ago

Researching the cause of hair loss and treating it by preventing DHT in the scalp with medication such as finasteride or dutasteride, estrogen, minoxidil, dermarolling, and possible topical antiandrogens.

community ORAL MIN ,DERMAROLLING AND RU58841 PROGRESS 3 months (18,M)

in Progress Pictures 80 upvotes 1 year ago

The conversation is about an 18-year-old's progress with hair regrowth using oral Minoxidil, dermarolling, and RU58841 over three months, starting treatment after beginning to lose hair at 16. Participants are impressed with the improvement and encourage continued treatment.

community hair loss treatment alternatives and ideas to improve gain

in Treatment 3 upvotes 1 year ago

The post discusses using finasteride, minoxidil, ketoconazole, and a dermaroller for hair loss, along with spearmint capsules, pueraria mirifica, saw palmetto, biotin, and vitamins. The user is also considering microdosing finasteride with trans treatment and mentions the potential of herbal enemas and hair systems.