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      community Galenic lotion. Science behind the components

      in Treatment  1 upvotes 1 year ago
      A user is considering a hair loss treatment lotion containing minoxidil, adenosine, caffeine, melatonin, and azelaic acid, questioning the interaction between caffeine and adenosine receptors. Another user suggests adding a topical anti-DHT ingredient like spironolactone, noting it should not be taken orally by men.

      community Regimen proposal (incl. dut meso) (event industry)

       1 upvotes 1 year ago
      A user in their early 20s is concerned about minor hair thinning and is considering a hair loss regimen involving PRP sessions, mesotherapy with dutasteride injections, and low-dose finasteride. They dislike minoxidil due to its greasiness and prefer a routine that is easy to maintain.

      community Topical Hyper-responder not responding to oral

      in Finasteride/Dutasteride  127 upvotes 4 months ago
      A user experienced significant hair loss after switching from topical to oral finasteride and minoxidil, despite initially seeing great results with the topical treatment. They are seeking advice on whether to return to topical treatments or increase their oral minoxidil dosage.

      community Potential pp405 info next week at masters of athetics

       53 upvotes 9 months ago
      Discussion on hair loss treatments, focusing on pp405, with skepticism about its effectiveness and concerns about its association with the cosmetic industry. Users also mention treatments like Minoxidil and Finasteride.

      community Anyone here tried topical spironolactone?

       4 upvotes 1 year ago
      Topical spironolactone was ineffective for hair loss according to one user who tried 2% nightly for a few months. The user reported no results.

      community Research behind RU-58642? Has anyone heard of this?

      in Research/Science  1 upvotes 1 year ago
      RU-58642 is a powerful anti-androgen that was not developed further, possibly due to safety concerns or financial reasons. RU58841 is a topical alternative, but it is less effective than finasteride and dutasteride, and its long-term effects are not well-studied.

      community Sudden dutasteride and OM shed after 1.5 yrs

       33 upvotes 3 weeks ago
      The user experienced significant hair shedding after 1.5 years on dutasteride and oral minoxidil, possibly due to a shedding cycle or lifestyle changes like nicotine use and creatine. Opinions vary on whether creatine contributes to hair loss, with some attributing shedding to synchronized hair cycles or genetic factors.

      community Best science-backed supplements for androgenetic alopecia? Looking for real evidence

      7 months ago
      The conversation discusses treatments for androgenetic alopecia, focusing on evidence-based supplements to complement finasteride. Suggestions include oral minoxidil, saw palmetto, pumpkin seed oil, tocotrienols, and various other supplements, while emphasizing the importance of scientific backing and cautioning against saw palmetto if already using finasteride.

      community Would this DUT work? Or just BS

       24 upvotes 3 weeks ago
      The conversation discusses the effectiveness and side effects of using Dutasteride, particularly at higher doses like 2.5mg, for hair loss treatment. Concerns are raised about potential side effects, long-term safety, and the difference between topical and oral applications.

      community Progressive insomnia (treatment-resistant) due to Finasteride

       8 upvotes 4 years ago
      A medical student experienced hair loss slowing with Finasteride but developed severe, treatment-resistant insomnia. They tried various medications with little effect, suspecting Post-Finasteride Syndrome, and others suggested the insomnia might be linked to Finasteride's impact on neurosteroids.

      community Hair texture very thin anything that would help long hair to thicken?

       4 upvotes 3 years ago
      The user is seeking ways to thicken their fine, thin hair and is considering treatments like spironolactone, minoxidil, and microneedling. They are currently using oral spironolactone, topical minoxidil, and ketoconazole shampoo, and are exploring additional options like alfatradiol and adjusting their treatment regimen.

      community Does anyone get blood tests while taking Finasteride to ensure thing are working appropriately (e.g. DHT is decreasing and estrogen isn't increasing significantly)

      in Finasteride/Dutasteride  11 upvotes 1 year ago
      People are discussing the use of finasteride for hair loss and the importance of hormonal blood testing to monitor effects like changes in DHT and estradiol levels. Some users also mention using minoxidil and the potential side effects of estradiol, such as gynecomastia, especially at higher doses.

      community Hair loss steps, guide to beginners or anyone experiencing hair loss

      in Treatment  1 upvotes 1 year ago
      The conversation discusses a hair loss treatment regimen involving finasteride, dutasteride, spironolactone, bicalutamide, oral estradiol, microneedling, and minoxidil. The regimen aims to reduce androgenic alopecia by blocking DHT and androgens, with a caution about potential feminizing effects.

      community october 2025 - may 2026 a bit of balding but I have restored my hair

       190 upvotes 3 months ago
      The user restored their hair using 5% minoxidil liquid, a 5 mg minoxidil pill, and dutasteride, experiencing no side effects. Others shared mixed experiences with dutasteride and finasteride, noting side effects like reduced libido and erection issues.

      community If PP405 works it will be fkn impossible to buy it.

       103 upvotes 10 months ago
      PP405 is a potential hair loss treatment that may activate dormant hair follicles, but there are concerns about its effectiveness, cost, and side effects. Users discuss treatments like minoxidil, finasteride, and RU58841, expressing skepticism about PP405's long-term success and accessibility.

      community Am I missing something with pp405?

       34 upvotes 1 year ago
      PP405 is discussed as a potential hair growth stimulant, possibly more effective than minoxidil, but not a cure for hair loss. There is skepticism about its ability to regrow "deadzones," and concerns about its impact on those with hair transplants.

      community Increased hairfall and i am scared

       7 upvotes 1 week ago
      The user is experiencing increased hair loss despite using minoxidil and spironolactone, and is concerned about low vitamin B12, D3, and ferritin levels. A doctor advised continuing minoxidil, but the user is worried about prolonged shedding.

      community Can a test cycle cause hairloss with 2.5 mg dutasteride?

       3 upvotes 8 months ago
      Increasing dutasteride to 2.5 mg daily and adding 2.5 mg oral minoxidil to prevent hair loss during a testosterone cycle. Suggestions include adding RU58841 for better protection against hair loss.

      community Ulo low dose dut/fin hair serum

       4 upvotes 9 months ago
      The user experienced severe sexual side effects from topical finasteride with minoxidil but found no side effects with low-dose dutasteride and finasteride serums from Ulo after a hair transplant. They also used a hair growth serum with saw palmetto without side effects.

      community I cry every day, everything is very depressing

      in Finasteride/Dutasteride  52 upvotes 1 year ago
      A user is experiencing hair loss despite using dutasteride and oral minoxidil, feeling hopeless and considering a hair system. They are advised to try ketoconazole, seek a second opinion from a dermatologist, and consider treatments like finasteride, RU58841, and hair transplants.

      community Testicular Ache

       3 upvotes 7 years ago
      The user has been taking 0.5 mg of finasteride daily for two months and is experiencing testicular ache, which they believe might be related to the medication. They plan to continue the treatment for a few more months despite the discomfort, hoping the side effects will subside.