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GlossaryHydroxyl Radicals

highly reactive molecules damaging cells and DNA

Hydroxyl radicals (OH radicals) are highly reactive molecules that contain one oxygen and one hydrogen atom. They are often formed during the breakdown of water molecules by ultraviolet light or through certain chemical reactions. In biological systems, hydroxyl radicals can cause significant damage to cells, proteins, and DNA, contributing to aging and various diseases, including those affecting hair health and potentially leading to conditions like alopecia.

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community Looking to make my own 2-Deoxy-D-ribose. Any science bros can give advice?

in Research/Science 7 upvotes 5 months ago

A user is making a 2-Deoxy-D-ribose solution and asks if it can be put into an oil instead of a gel, considering adding hydrocortisone and retinoic acid. They seek advice on the best carrier oil for hair growth.

community My Theory Regarding a Cause and Cure for Androgenetic Alopecia

in Treatment 97 upvotes 4 years ago

Hair loss theory suggests imbalance between Vitamin D Receptor (VDR) and Androgen Receptor (AR) activation. Proposed treatment includes upregulating VDR, downregulating AR, and improving mitochondrial health.

community 6 Month Progress Pics - Dutasteride

in Progress Pictures 140 upvotes 1 year ago

The conversation discusses hair loss and the use of Dutasteride for treatment. One participant strongly supports the use of Dutasteride.

community Help needed with finding an alternative to my dermatologist's recommendation ( shampoo and conditioner)

6 years ago

A user is seeking alternatives to **Curatio Triclenz Hair Cleanser** and **Triflow Hair Conditioner** due to issues with hair weight and scalp pimples. They need recommendations for mild shampoos available in Europe, preferably Sweden.

community The Worst Hair Loss Condition You (MAY) have: LPP

in Research/Science 43 upvotes 4 months ago

Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.

community PSA: Get your Vitamin D levels checked!

in Treatment 114 upvotes 1 year ago

A user improved their hair health by taking 50,000 IU of vitamin D3 weekly due to a deficiency. Others discussed the potential link between vitamin D and hair growth, with some sharing similar experiences and emphasizing the importance of monitoring vitamin D levels and consulting with doctors.

community The theory that explains everything. Please help me make this big!

in Research/Science 2448 upvotes 3 years ago

The post and conversation are about the role of the enzyme 3alpha-hydroxysteroid reductase in hair loss and the potential of compounds like procyanidin B2 and sulforaphane to boost its activity for hair regrowth. Further research is needed to develop effective treatments based on this theory.