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      community I have Post PP405 Syndrome(PPS). Should I start a foundation?

       32 upvotes 1 year ago
      The conversation humorously discusses the fictional "Post PP405 Syndrome" and the idea of starting a foundation or cult around it. It mentions skepticism about the effectiveness of PP405 and jokes about future therapies.

      community Unused Eucapil- anyone want it?

      in Product  1 upvotes 1 year ago
      The conversation is about a user offering free unused Eucapil after switching to finasteride for hair loss treatment. The user did not use Eucapil and is willing to give it away locally or ship it if costs are covered.

      community How to source winlevi? Not generica

      in Product  1 upvotes 4 months ago
      The conversation is about sourcing Winlevi (clascoterone) for personal use in the EU. The user is specifically looking for a non-generic version.

      community Any chemists want to manufacture PP405 / JXL069? (Steps inside)

       89 upvotes 10 months ago
      The conversation discusses the synthesis and potential use of JXL069 and PP405 for hair loss treatment, with skepticism about their effectiveness and concerns about safety. Users mention that JXL069 has shown no results in hair growth, and there is confusion about its identity and effectiveness compared to PP405.

      community Anyone tried GHK-CU for hair loss?

      in Treatment  6 upvotes 1 year ago
      The conversation is about using GHK-Cu, a copper peptide, for hair loss treatment. Users discuss their experiences, dosages, and additional benefits like improved skin and energy.

      community PELAGE PHASE 2 TRIALS FOR PP405 - Volunteers Needed

       24 upvotes 2 years ago
      PP405 is a topical gel being tested for hair regrowth in adults with androgenetic alopecia. Volunteers aged 18-55 are needed for a 16-week trial in several US locations.

      community (MTF 35) 20 Months Feminizing HRT

      in Transgender  18 upvotes 6 months ago
      A 35-year-old transgender woman experienced hair regrowth with feminizing HRT, adding dutasteride and bicalutamide, and plans a hair transplant for further improvement. Estrogen also improved skin appearance, and the user advises against cisgender men using feminizing HRT for hair regrowth.

      community GT20029 China Phase II Trial For AGA Reached Primary Endpoint

       133 upvotes 2 years ago
      The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.

      community Any active Kx-826 Pyrilutamide group buys happening?

       10 upvotes 4 years ago
      The conversation discusses organizing group buys and tracking progress for Kx-826 Pyrilutamide, a hair loss treatment. Participants express optimism about upcoming results and concerns about self-reporting bias.

      community DUPA - Impossible to cure, so giving up

      in Update  3 upvotes 11 months ago
      The user diagnosed with DUPA tried treatments like dutasteride, finasteride, RU58841, and minoxidil without success and is considering a hair system. They hope for a future cure, possibly with PP405, and others suggest options like scalp biopsy and SMP.

      community 2 years on fin - switching to dut and treating SD

       44 upvotes 2 months ago
      The user plans to switch from finasteride to dutasteride for hair loss and is treating seborrheic dermatitis with Nizoral and Stanhome Balance shampoos. They are considering trying Vichy Psolution shampoo and Ciclopirox, and are dealing with challenges due to Vietnam's humidity.

      community Who is the ideal target for PP405? Will it render hair trasplants obsolete?

       2 upvotes 5 months ago
      PP405 is being discussed as a potential treatment for hair loss, with uncertainty about its effectiveness compared to existing treatments like finasteride, dutasteride, and minoxidil. There is cautious optimism, but its impact on hair transplants remains unclear.

      community Today, The DHT Attacked

       41 upvotes 8 years ago
      The conversation humorously discusses the effects of DHT on hair loss, with references to treatments like finasteride and RU58841. Users share exaggerated stories about DHT's impact, highlighting its negative reputation.

      community *11 month update* 1st pic 11 months ago vs today. 2nd pic same timeframe but wet hair. 3rd pic my hair at my worst back in 2020. 4th pic under bright lighting & camera flash. 5th pic hairline. 6th & 7th pic side/back view. 8th pic good hair day.

      in Progress Pictures  498 upvotes 2 years ago
      The user shared impressive hair regrowth results after 11 months using topical finasteride and minoxidil from HIMS. Many users congratulated the progress and inquired about the application method, brand, and potential side effects.

      community The homeless crackhead protocol

       4487 upvotes 1 year ago
      The conversation humorously suggests that drug use might be more effective for hair retention than traditional treatments like minoxidil or finasteride. It attributes full heads of hair in homeless individuals to lifestyle factors like reduced stress or hormonal changes.

      community *Update* month 14. First 4 pics are before i started my treatment. Still would like to see improvement by the crown & corners of my hairline hopefully.

      in Progress Pictures  298 upvotes 1 year ago
      The user has been using HIMS topical finasteride and minoxidil spray for hair loss, with positive results but still seeks improvement at the crown and corners. They are considering reintroducing derma rolling and possibly trying oral treatments like dutasteride due to concerns about shedding and irritation.

      community I think this is my stop, gentlepeople. So long and thanks for all the data 👋

       2264 upvotes 1 year ago
      A user shared their successful experience with hair regrowth and transitioning from male to female using minoxidil, finasteride, Nutrafol, microneedling, and hormone replacement therapy (HRT). They expressed gratitude for the results and encouraged others to explore treatments that align with their personal goals.

      community The expected timeline for PP405 - Next update at AAD Annual Meeting in March 2026 ?

       34 upvotes 8 months ago
      A new hair loss treatment, PP405, showed promising Phase 2a results with 31% of patients experiencing over 20% hair density increase without systemic absorption, avoiding hormonal side effects. The treatment is expected to be expensive, with Phase 3 trials starting mid-2026, and there is skepticism about the data's strength.

      community ru58841 in europe, without getting water in the mail.

       1 upvotes 6 months ago
      The conversation is about finding a trustworthy and affordable source for RU58841 in Europe, with a comparison between Anagenic and Actifolic. The user seeks experiences from others in the EU to avoid receiving water instead of the product.

      community Now i want to see if this DHT survives

      in Treatment  33 upvotes 1 year ago
      The conversation discusses using minoxidil, finasteride, spironolactone, and RU58841 for hair loss treatment. Users share experiences with these treatments, noting side effects and varying effectiveness.

      community Anyone looking at peptides for hair?

       9 upvotes 7 months ago
      The conversation discusses interest in peptides for hair loss, specifically mentioning ahkCU and ghkCU. A user is considering adding ghkCU to their treatment regimen.

      community Hydrophobic Finasteride. Why don’t we have it?

       6 upvotes 1 year ago
      The conversation discusses the potential benefits of creating a hydrophobic version of finasteride to reduce systemic side effects while maintaining scalp health. It compares this idea to fluridil, which is designed to be hydrophobic and has less systemic absorption.

      community My Delusional Hope - This page becomes irrelevant in 2030s

       54 upvotes 10 months ago
      People are hopeful for a permanent hair loss solution by the 2030s, considering options like hair cloning and treatments like pp405. Synthetic hair transplants have been attempted but are not effective long-term.

      community Now That PP405 Hype is Gone What is Everyone Coping with as the Next Cure?

       41 upvotes 1 month ago
      People are discussing various hair loss treatments, including finasteride, minoxidil, RU58841, and new potential treatments like vdphl01, ABS-201, and KX-826. Some express hope in future developments like hair cloning and CRISPR, while others emphasize acceptance and sticking with current treatments.

      community literally dht beef bruhhsmhmmhh😡😡😡😡😡😤

      in Finasteride/Dutasteride  128 upvotes 1 year ago
      The conversation discusses using finasteride, dutasteride, RU58841, and testosterone to combat hair loss and block DHT, with some users expressing concerns about side effects and vegan options for medication. The discussion also touches on personal experiences with hormone treatments and the desire to maintain a youthful appearance.

      community Didn’t wear a hat to work today - 4 months Topical 0.3/6% Fin/Min in

      in Progress Pictures  210 upvotes 1 year ago
      The user shared progress after four months of using a topical treatment with 0.3% finasteride and 6% minoxidil from Hims, noting positive results and considering switching to oral medication for convenience. Other users discussed the effectiveness of minoxidil and finasteride, emphasizing that first-time users often see the best results, and shared personal experiences with hair regrowth and maintenance.

      community Veradermics VDPHL01: why isn’t anyone talking about it?

      in Treatment  42 upvotes 1 year ago
      Veradermics' new hair loss treatment, VDPHL01, is likely a modified release oral minoxidil, which has received $75 million in funding for clinical trials. Despite skepticism about investing in a known treatment, some believe it could offer improved efficacy and reduced side effects.

      community Norwood 7 progress 3.5 months on topicals

       14 upvotes 4 months ago
      The conversation discusses hair regrowth progress using topical dutasteride with cetirizine, laser therapy, and growth serum. The user observes miniaturized, vellus hairs on the scalp.