The user discusses using Minoxidil for hairloss and is considering RU58841 to reduce excessive oil production. They seek advice on RU58841's effectiveness in blocking sebum production.
A 19-year-old male has been losing hair since 16-17 and feels more depressed after 6 months of using topical minoxidil and finasteride, which made his hair dry and greasy. Another user suggested switching to oral finasteride and provided tips for using topical minoxidil to reduce greasiness.
A user shared their progress after 8 months of using oral dutasteride, minoxidil, and ketoconazole shampoo for hairloss. They are very pleased with the results.
The conversation discusses the mechanism of action of alfatradiol (17 alpha estradiol) in treating hairloss. It explores theories that it either inhibits 5 alpha reductase to prevent T->DHT conversion or aromatizes scalp T into 17-alpha-estradiol to save hair.
The conversation discusses why there are no FDA-approved NSAAs like RU58841 on the market, despite their potential superiority to 5AR inhibitors like finasteride. It explores the effectiveness of treatments like Minoxidil, finasteride, and RU58841 for hairloss.
The conversation discusses HMI 115, a new hairloss treatment with promising results, showing a significant increase in hair density after two months. Some users are skeptical, while others are hopeful for its release and potential affordability.
The user discusses their long struggle with hairloss, considering various treatments like hair transplants, hair systems, and natural methods such as micro-needling, vitamin supplements, and a healthy lifestyle. They express concerns about side effects from drugs like finasteride and ultimately lean towards using a hair system for better appearance and confidence.
The conversation discusses taurine supplements for hair growth, highlighting their potential to reduce DHT and improve hair health. A user comments that people often try alternatives to finasteride.
The conversation discusses whether 2.5mg of dutasteride or 200mg of testosterone weekly is more influential in preventing hairloss, with various personal experiences indicating that the effectiveness is dependent on the individual's genetic profile. Some users report that dutasteride is likely to be more effective at the given doses.
A natural compound called C3A from Aronia Chokeberry can help prevent hairloss by counteracting the effects of DHT. The user has been taking 50 grams of dried organic Aronia Chokeberry daily for 30 days and will update with photos in 60 days.
A user shared their 9-month post-hair transplant results with 4600 grafts, using only Nourkin hair vitamins, Vitamin D, and B12, and expressed satisfaction. The replies debated the necessity of medications like finasteride and minoxidil for maintaining hair health.
Minoxidil helps hair growth on both scalp and face, but stopping it leads to hairloss on the scalp, not the face. The user questions why scalp hair can't be maintained with finasteride or androgen blockers after stopping minoxidil, despite these treatments reducing DHT damage.
A person shared their 3-month hair regrowth progress using 1mg finasteride daily, a topical solution with finasteride, minoxidil, and tretinoin, and weekly microneedling. They regret not starting treatment earlier, and a reply agrees that early treatment is beneficial.
The conversation discusses the failure of Phase 3 trials for the hairloss treatment KX-826, with no significant difference found between the drug and placebo. Some users express disappointment and skepticism, while others discuss alternative treatments like Minoxidil, finasteride, and RU58841.
The user is using oral finasteride, topical minoxidil, Nizoral, dermarolling, a hair thickening conditioner, and hair vitamins for hairloss treatment. They stopped taking testosterone due to medical reasons and are now technically on estrogen, but it's unclear if this impacts their hair growth.
The user has been using a strong combination of hairloss treatments for 16 months, including Finasteride, Minoxidil, Dutasteride, and RU-58841, but their hairloss has worsened. They're questioning whether their high testosterone levels or residual scalp DHT are causing further hairloss, with a reply suggesting that even small amounts of DHT can cause hairloss if one is sensitive to it.
Pyrilutamide is believed to be more effective than RU58841 and 1 mg finasteride in treating hairloss, with no systemic hormonal effects and the potential to block more than 31% of scalp DHT. It may also antagonize scalp testosterone due to its action as an androgen receptor antagonist.
A user is using RU58841 and pyrilutamide for hairloss and is seeing their hairline return, but the process is slow. They also mention using finasteride and dutasteride, with finasteride causing reduced libido but no noticeable side effects from RU58841 or pyrilutamide.
Isotretinoin may cause hairloss by increasing DHT through a precursor androgen, DHEAS. Treatments like topical antiandrogens (RU58841, pyrilutamide) and drugs increasing PPAR-y expression (pioglitazone) might prevent this hairloss.
Iron or vitamin deficiencies can lead to decreased hair diameter, not just androgenetic alopecia. Treatments discussed include Minoxidil, finasteride, and RU58841.
The user is seeking advice on which treatment to add to their current regimen for male pattern baldness. They have previously tried Dutasteride, Nizoral, and oral Minoxidil, but experienced continued hairloss. They are specifically asking for experiences with RU58841, Stemoxydine, or Alfatradiol.
The user updated their hairloss treatment to include daily dutasteride, oral minoxidil, topical dutasteride with minoxidil and tretinoin, and RU58841. Commenters feel the extensive treatment is unnecessary for the user's level of hairloss.
The post discusses the potential of GT20029 in treating hairloss, questioning if it will replace finasteride or be used alongside existing treatments. A reply indicates that its role is still uncertain.
Hair is growing faster after 2 weeks of using topical vitamin D3 in alcohol/oil. The user plans to continue the experiment for 3 months before giving a full review.
User switched from finasteride to combination dutasteride and finasteride for hair density improvement. They noticed less hair shedding and more youthful skin, with a reply suggesting less DHT could increase elastin in skin.
A user's experience taking finasteride, which resulted in them having an unexpected emotional reaction, and the replies to this post focus on the humorous aspects of cautionary tales about hairloss treatments.
The user has tried minoxidil, finasteride, dutasteride, tretinoin, and microneedling for hairloss without success and is considering taking 2.5 mg of minoxidil orally by mixing it with bottled water, questioning if this affects the solution's stability.
A new Latanoprost-based formula used by Hollywood celebrities to treat hairloss, with the formula containing minoxidil, tretinoin, melatonin, azelaic acid, zinc thymulin, vitamin B6, sandalore and methyl vanillate. It also mentions the potential of offering a combined sublingual minoxidil/oral dutasteride option in the future.
How little the average person knows about hairloss and how it can be an unfairly stigmatized issue, even by people with little knowledge of it themselves. Some specific treatments that were discussed include finasteride, RU58841, dutasteride, minoxidil, pyritinol, dermarolling, and diet/lifestyle changes.