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GlossaryEndocrine System (hormonal system)

network of glands releasing hormones to regulate body functions

The endocrine system, also known as the hormonal system, is a network of glands and organs that produce, store, and release hormones directly into the bloodstream. These hormones regulate various bodily functions, including metabolism, growth, reproduction, and mood. Key components include the thyroid gland, adrenal glands, pituitary gland, and pancreas.

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community Started Finasteride almost three months ago and I'm upset

in Update 153 upvotes 9 months ago

A user started taking finasteride three months ago to treat hair loss and unexpectedly cleared their acne, which they had been struggling with since age 12. The conversation includes others sharing their experiences with finasteride, its effects on acne and hair loss, and mentions a related treatment, clascoterone, for acne and hair loss.

community New update. 16 months on finasteride, 25 year old, 1.25mg daily. The first picture is a screenshot from a video taken in February 2023, hence the quality is kinda poor.

in Progress Pictures 418 upvotes 6 months ago

A 25-year-old user shared progress pictures after 16 months of using 1.25mg daily finasteride for hair loss, reporting noticeable results around months 4-5 and some initial side effects that resolved. The user experienced thickening and slight regrowth of the hairline.

community 1M Minoxidil, Stemoyxidine, Alfatradiol, Microneedling

in Progress Pictures 28 upvotes 4 years ago

A user trying various treatments for hair loss, such as minoxidil, stemoyxidine, alfatradiol, and microneedling, with plans to add tretinoine and finasteride.

community 16 months finasteride & minoxidil progress

in Progress Pictures 605 upvotes 5 months ago

User shared 16-month progress using finasteride 1 mg/day and minoxidil 5% solution once/day, noting significant regrowth, especially in temporal peaks. Users discussed shedding, side effects, and positive feedback from others.

community Does age play a role in how you respond to 5AR inhibitors? (finasteride/dutasteride)

in Research/Science 24 upvotes 8 months ago

The conversation discusses whether age affects the side effects and effectiveness of hair loss treatments like finasteride and dutasteride. Some believe early treatment yields better results, while others mention varied outcomes across ages and personal regrowth experiences without a clear consensus on age impact.

community My Research Compilation on Nutrafol

in Research/Science 11 upvotes 2 years ago

Nutrafol, a hair loss supplement, has limited and potentially biased research, with one study showing a 10% increase in hair count for women after 6 months but no significant results for men. The user concludes that cheaper, well-studied options like minoxidil may be more effective, especially for men, given the lack of evidence supporting Nutrafol.

community Case study: 1mo progress microneedling + minox, no fin.

in Microneedling 6 upvotes 4 years ago

A user shared their experience with microneedling and minoxidil for hair loss, avoiding finasteride due to concerns about systemic hormone effects. They reported slight hair regrowth after one month and plan to continue the regimen, noting improvements in skin sensitivity and managing dandruff with anti-dandruff shampoo.

community In three years time we'll still be in roughly the same place with regardless to treatments as we are now - and it will be the fault of all of us.

in Chat 16 upvotes 3 years ago

User discusses frustration with hair loss treatments and lack of progress. Emphasizes importance of measuring blood hormone levels to understand treatment effectiveness and side effects.

community Why are there no FDA approved NSAA's yet?

in Research/Science 7 months ago

The conversation discusses why there are no FDA-approved NSAAs like RU58841 on the market, despite their potential superiority to 5AR inhibitors like finasteride. It explores the effectiveness of treatments like Minoxidil, finasteride, and RU58841 for hair loss.

community New Fluridil group buy

in Product 7 upvotes 3 years ago

A group buy for products to treat hair loss, such as Minoxidil, Finasteride and RU58841. Participants are interested in adding more people before ordering the next order.

community to all people who cannot tolerate anti androgens (loe dose topical fin, pyrilutamide, CB) i am getting desperate, looking for a solution

in Research/Science 13 upvotes 1 year ago

The user tried Minoxidil without success, and Finasteride worked but caused sexual side effects even at a very low dose. They are seeking alternative treatments for hair loss as they cannot tolerate anti-androgens and are also in therapy for mental health.

community Starting pyrilutamide. Currently have a 2 month supply. I will actually log my results here unlike the others

in Treatment 112 upvotes 2 years ago

Transitioning from finasteride to Pyrilutamide as a treatment for hair loss, and the potential risks associated with taking such a drug. People have discussed the need to wait at least 6 months in order to assess results, and are willing to risk their health trying this new medication.

community Topical Finasteride reduced my DHT more than Oral Dutasteride

in Finasteride/Dutasteride 42 upvotes 2 years ago

Treatments for hair loss, including the experiences of topical finasteride and oral dutasteride. It also discusses Pyrilutamide, 0.025% topical concentration, Minoxidil, RU58841, and 1% finasteride gel dosage.

community DHT and 5AR respect post, it's importance within the brain

in Research/Science 111 upvotes 9 months ago

The conversation discusses whether to use finasteride for hair loss, considering its role in inhibiting DHT and 5AR, which can affect brain function and mood. Some users report anxiety and depression from finasteride, while others do not experience these side effects and emphasize the importance of DHT for brain and prostate health.

community starting out Nizoral shampoo, do I buy more bottles after I finish or switch back to traditional shampoo?

in Ketoconazole 62 upvotes 2 years ago

Using Nizoral shampoo intermittently and reassessing scalp condition after each bottle, potentially adding in other tools to target seb derm, and alternating between Pura D'Or and Nizoral for a healthy and clean scalp.

community 0.5mg Dutasteride promotes more “regrowth” than 5mg oral Minoxidil

in Research/Science 117 upvotes 10 months ago

Dutasteride promotes more hair regrowth than Minoxidil. Users discuss combining treatments for better results and share personal experiences with side effects.

community Trestolone (MENT) as a nuclear treatment

in Treatment 99 upvotes 2 years ago

Experimenting with trestolone as a treatment for hair loss in an attempt to avoid DHT-related treatments such as finasteride and dutasteride, and discussing the potential effects of its receptor selectivity on the androgen receptors in the scalp.

community Estradiol mesotherapy / idea feedback

in Female 6 upvotes 3 weeks ago

The conversation discusses using estradiol mesotherapy to replicate hormone replacement therapy results while minimizing systemic exposure. It also covers the use of Spironolactone cream, which reportedly has no systemic side effects, and the potential risks of using bicalutamide and Spironolactone in men.

community What makes breezula different than formula 82f?

in Question 8 upvotes 4 years ago

Breezula (clascoterone) and Formula 82F (topical finasteride) are treatments for hair loss that block DHT differently; Breezula competes with DHT at the hormone receptor site without systemic effects, while 82F inhibits the enzyme that converts testosterone to DHT. Breezula may work for those who don't respond to finasteride and vice versa.

community My Hair System Journey, Part 4

18 upvotes 5 years ago

The user shares their experience with a hair system, noting no one noticed the change except their girlfriend. They discuss the learning curve, maintenance tips, and their satisfaction with the results, feeling more confident and optimistic.

community Topical Pyrilutamide - Hormone Panel

in Treatment 2 upvotes 1 year ago

The user used 0.5 mL of 0.5 mg of Pyrilutamide for 60 days for hair loss, but didn't notice any hair growth. They shared their hormone panel results and are seeking advice on next steps.

community A systematic bro-science review of DHT, 5AR, neurosteroids, sexual health and 5AR inhibitors

in Research/Science 37 upvotes 2 years ago

Hair loss treatments, specifically 5AR inhibitors, can impact neurosteroids and sexual health. The effects of topical fin/dut on tissue-specific DHT levels are unclear.

community Please take a vitamin & hormone test

in Chat 256 upvotes 1 week ago

Checking vitamin and hormone levels is important for addressing hair loss, as deficiencies in vitamin D, zinc, and iron can affect hair growth. Treatments like finasteride, minoxidil, and vitamin supplements are used, but addressing deficiencies is crucial for effectiveness.

community Damn, the trash hormone DHT was losing so hard it pulled the "old social media post" card

in Chat 196 upvotes 6 months ago

The conversation is about hair loss treatments, including minoxidil, finasteride, dutasteride, tretinoin, stemoxydine, adenosine, castor oil, baicalin, and bimatoprost. The user shares their nightly and morning routines and discusses the role of DHT in hair loss.

community Could you tell this is a hair system?

in Technology 307 upvotes 1 year ago

A user who was losing their hair and found an effective solution; they asked for opinions on it and discussed treatments such as Minoxidil, Finasteride, and RU58841, as well as SMP.

community My Ultimate Hair Regrowth Regimen: Minimizing Systemic Exposure While Maximizing Results

in Research/Science 16 upvotes 3 months ago

The regimen includes using a diluted 5.5% Minoxidil / 0.025% Finasteride solution daily, microneedling weekly, and ketoconazole shampoo twice a week to minimize systemic exposure while maximizing scalp DHT reduction. The goal is to achieve hair regrowth with minimal side effects.

community I’m going balls to the wall with probably the most nuclear stack apart from hormone blockers, will update this thread monthly.

in Treatment 52 upvotes 2 years ago

A user experimenting with an extreme hair loss treatment stack of Dutasteride, RU58841, 15 mg oral minoxidil, and microneedling, which sparked a debate among other users about the safety of this approach.

community At this point in my life, being bald is not for me. I'm going back on to hair systems...

25 upvotes 4 years ago

28-year-old struggles with aggressive hair loss since 18, used minoxidil with limited success. Tried hair systems but found them expensive, shaved head for job interviews but plans to return to hair systems.

community Topical finasteride has affected my hormones

in Finasteride/Dutasteride 27 upvotes 11 months ago

A 21-year-old experienced hormone changes after using self-made topical finasteride for hair loss, including a 20% decrease in DHT, a 47% increase in testosterone, and a 39% increase in estradiol. The user previously used minoxidil and microneedling but is now seeking ways to balance hormones, possibly through supplements or dosage adjustments.

community 26M Baseline blood work done before Finasteride

in Finasteride/Dutasteride 8 upvotes 3 years ago

A person considering finasteride for hair loss checked their hormone levels before starting treatment. They are concerned about the potential increase in estradiol and its effects, as well as the impact on their sex hormone-binding globulin (SHBG) and free testosterone levels.