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      community Tretinoin Efficacy Alone for Hair Regrowth + DHT blocker

      in Minoxidil  5 upvotes 2 years ago
      Tretinoin's effectiveness for hair regrowth alone is questioned, with interest in its use with oral minoxidil. The discussion also considers whether finasteride or dutasteride is the better DHT blocker and if switching to dutasteride is advisable for those without side effects from finasteride.

      community It looks like Pelage are giving hints that PP405 is a game changer

      in Chat  239 upvotes 5 months ago
      PP405 is seen as a potential breakthrough for converting vellus hairs to terminal hairs, with users expressing both hope and skepticism. It is compared to treatments like minoxidil and finasteride, with discussions on side effects and marketing concerns.

      community Serum based on plant extracts boosts hair growth in weeks.

       44 upvotes 11 months ago
      A serum containing Centella asiatica extracellular vesicles, IGF-1, FGF-7, and caffeine significantly improved hair thickness, density, length, and reduced hair loss after 56 days. The conversation also discusses how treatments like finasteride, minoxidil, and ketoconazole address different aspects of hair loss by reducing DHT, improving blood flow, and lowering inflammation.

      community Dermatologist visit+prescription

      in Treatment  3 upvotes 11 months ago
      A dermatologist prescribed 0.5mg dutasteride every two days and 5mg Minoxidil daily for hair loss, suggesting dutasteride mesotherapy as an alternative. The discussion questions the effectiveness and cost of mesotherapy compared to oral treatments, with concerns about side effects and the dermatologist's approach.

      community Ashwagandha for Hair Loss: Any Real Results Matching Study Claims?

       5 upvotes 2 years ago
      Ashwagandha may help with hair loss by regulating thyroid function and reducing stress, but its effectiveness compared to finasteride or minoxidil is debated. Some users report positive effects on hair health, while others are skeptical of its benefits.

      community I saw results in just 10 days ..

      in Minoxidil  6 upvotes 5 months ago
      The user reported noticeable hair thickening after 10 days of using oral minoxidil and finasteride, but others suggested it might be an April Fool's joke or a placebo effect. The user also mentioned a high protein intake and regular gym workouts, while others discussed concerns about finasteride's side effects.

      community Which 2026 hair‑loss treatments have the strongest evidence so far? (minoxidil/finasteride vs. clascoterone, PP405, Re:You’s NV‑623/624, AMP‑303, RU58841)

       44 upvotes 3 months ago
      Minoxidil and finasteride are the only FDA-approved treatments for androgenetic alopecia, while newer treatments like clascoterone, PP405, NV-623/624, AMP-303, and RU58841 are still experimental with varying levels of evidence. Clascoterone shows the most promise due to strong human data, while AMP-303 has notable early human trial results; RU58841 lacks human data and remains experimental.

      community Don’t Get Too Hyped About PP405. We've Seen This Movie Before.

       218 upvotes 1 year ago
      PP405 is a new hair loss treatment showing early promise with a 20% hair density increase, but skepticism exists due to past failures of similar treatments like Pyrilutamide, RU58841, and Bimatoprost. Users debate its potential effectiveness, with some hopeful due to Google's involvement, while others urge caution without more evidence.

      community Latest study on creatine and hair loss. 45 men, 3 months.

       378 upvotes 1 year ago
      Creatine does not significantly affect DHT levels or cause hair loss. Some users continue using finasteride and minoxidil while taking creatine, expressing skepticism about its impact on hair loss.

      community Ik I’ll get hate but I’ll say it anyway

      in Chat  111 upvotes 1 year ago
      A clean diet, including cutting sugar, gluten, and dairy, improved hair health and reduced shedding for a user on oral minoxidil and finasteride, but reverting to an old diet worsened hair condition. While diet impacts hair health, genetic factors and treatments like topical ketoconazole and hydrocortisone are also important for managing hair loss.

      community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

       63 upvotes 2 years ago
      Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

      community Car broke down after 6 years on oral fin

       915 upvotes 4 months ago
      Finasteride is humorously blamed for causing car problems and bizarre side effects. Users joke about switching to treatments like dutasteride and minoxidil.

      community I can’t believe the cure for hair loss costs like $35 A YEAR

      in Chat  288 upvotes 5 months ago
      Finasteride is effective and affordable for preventing hair loss but may cause side effects like low libido. Some users combine it with minoxidil for better results, while others consider alternatives like dutasteride due to side effects.

      community Will Breezula simply be an overhyped flop?

       15 upvotes 8 months ago
      Breezula is seen as potentially overhyped, with concerns about its cost, effectiveness, and long-term benefits compared to existing treatments like finasteride and minoxidil. Some users believe it could complement existing treatments, while others are skeptical about its impact and prefer waiting for newer options like GT20029 and PP405.

      community PP405 could be released before GTA 6

      in Chat  133 upvotes 9 months ago
      PP405 is discussed as a potential hair loss treatment, but its effectiveness and safety are uncertain. Some users express skepticism, while others are hopeful, comparing it to existing treatments like Minoxidil and Finasteride.

      community Can be this a new game changer? What's your Opinion about it

       528 upvotes 10 months ago
      The conversation discusses skepticism about new hair loss treatments, with many users expressing doubt about their effectiveness compared to existing treatments like minoxidil and finasteride. Some users mention natural oils like olive and macadamia oil, but overall, there's a consensus that these are unlikely to be game changers.

      community Is Finasteride the only way to reduce scalp DHT?

       28 upvotes 10 months ago
      A 24-year-old male experienced side effects like low libido and ED after starting finasteride post-hair transplant and is seeking alternatives to reduce scalp DHT. Suggestions include topical finasteride, Xpecia, DHT-reducing shampoos, and switching to dutasteride, with some users reporting fewer side effects with these alternatives.

      community What new hair-loss treatments actually look exciting right now (Oct 2025)

       171 upvotes 11 months ago
      New hair loss treatments include Breezula, PP405, ET-02, KX-826, GT20029, VDPHL01, and CosmeRNA, with some showing promise in reactivating stem cells and reversing greying. Breezula and VDPHL01 are highlighted as potential add-ons or alternatives to current treatments like finasteride and minoxidil.

      community Summary of future treatments from 2020

       51 upvotes 1 year ago
      Hair loss treatments include finasteride, minoxidil, microneedling, dutasteride, CB-03-01, RU-58841, and experimental options like KY-19382 and stem cell therapy. Some treatments are considered ineffective or risky, such as ketoconazole, PRP, and low-level laser therapy.

      community PP405 timeframe ? Could it replace current treatments ?

      in Update  34 upvotes 1 year ago
      PP405 is a potential new hair loss treatment that might replace finasteride and minoxidil, but it is still in clinical trials and may not be available until 2028-2031. There is skepticism about its effectiveness, with only a 20% increase in hair density observed in some participants.

      community Switch from fin to dut and its worse

       4 upvotes 1 year ago
      Switching from finasteride to dutasteride can worsen hair loss for some men due to increased testosterone levels. Topical treatments like RU58841 and Pyrilutamide are suggested to counteract these effects, but individual responses vary.

      community Dutasteride Infertility Debunked: Low T causes true infertility.

       168 upvotes 1 year ago
      Dutasteride and finasteride may temporarily affect semen quality but are unlikely to cause permanent infertility. The Kim et al. study is criticized for poor methodology, and many prefer hair retention over potential fertility concerns, using treatments like dutasteride, finasteride, and minoxidil.

      community Does DHT give you a leaner face?

      in Finasteride/Dutasteride  44 upvotes 1 year ago
      Finasteride and dutasteride may increase estrogen levels, leading to water retention and a fuller face. Users discuss managing these effects with lifestyle changes and supplements like zinc and DIM.

      community Recovered from dark finasteride side effects

       4 upvotes 4 years ago
      The user experienced severe side effects from finasteride, including depression and anxiety, but recovered with DHT injections, sleep medication, and Ayurvedic treatments. They now maintain hair health with minoxidil, PRP therapy, and a good diet, advising against self-diagnosis and recommending consulting a doctor.