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    GlossaryHormonal Imbalances (Hormonal Dysregulation)

    disruption in hormone levels affecting body functions and processes

    Hormonal imbalances occur when there is too much or too little of a hormone in the bloodstream, disrupting the body's normal functions. These imbalances can affect various bodily systems and processes, including metabolism, growth, mood, and reproductive health, and can be caused by factors such as stress, medical conditions, or changes in diet and lifestyle.

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      community Opinions on Scalp fibrosis and DHT?

      in Research/Science  9 upvotes 2 years ago
      The conversation discusses the theory that scalp fibrosis contributes to male pattern baldness (MPB) by increasing DHT concentration, and mentions treatments like Minoxidil. The user seeks opinions on the theory and the effectiveness of scalp massages.
      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 3 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Hormonal panel after 1 year of treatment - DHT levels doubled!!

      in Finasteride/Dutasteride  7 upvotes 11 months ago
      A 27-year-old man shared his hormonal panel results after one year of taking finasteride 1mg/day for hair loss, showing his DHT levels nearly doubled. He reported stabilized hair loss with mild side effects that resolved, and he is considering a hair transplant but is concerned about the increased DHT levels and potential treatment options.

      community The Hormonal Profile of MPB/AGA

      in Research/Science  9 upvotes 3 years ago
      Men with early male pattern baldness (MPB) may have hormonal abnormalities similar to those in women with PCOS. Specific treatments mentioned include Minoxidil, Finasteride, and RU58841.

      community Topical Dutasteride - Non-Hormonal, Side Effect Free 5ARI

      in Finasteride/Dutasteride  26 upvotes 3 months ago
      The conversation discusses the effectiveness and skepticism around topical dutasteride for hair loss, with mentions of combining it with other treatments like minoxidil and oral medications. Some users doubt its efficacy due to lack of independent studies and potential conflicts of interest.
      Topical Dutasteride - Non-Hormonal, Side Effect Free 5ARI?

      community Topical Dutasteride - Non-Hormonal, Side Effect Free 5ARI?

      in Treatments  372 upvotes 3 months ago
      Topical dutasteride is suggested as a low side-effect treatment for hair loss, with a proposed dose of 0.025% 1ml/day. It is considered better than finasteride due to its even inhibition of DHT isoforms and lower systemic absorption.

      community Using WinLevi (Clascoterone) for Seborrheic Dermatitis and Acne

      in Treatment  4 upvotes 9 months ago
      Winlevi (clascoterone) is discussed as a treatment for hormonal acne and seborrheic dermatitis due to its ability to block DHT and regulate sebum production. The post suggests that Winlevi could offer a novel approach for managing seborrheic dermatitis.

      community Hair loss 30F - thoughts on red light therapy vs min/fin?

      in Female  6 upvotes 1 month ago
      The conversation discusses hair loss treatments for a 30-year-old female, comparing red light therapy with minoxidil and finasteride. Concerns about hormonal impact and potential pregnancy are raised, with suggestions to consider spironolactone and microneedling, while emphasizing the importance of consulting a dermatologist.

      community Ru58841 for a female w male pattern baldness

      in General  166 upvotes 3 months ago
      A user is considering using RU58841 for female pattern baldness and is also planning to use Minoxidil. They are hesitant to ask their doctor for spironolactone due to its cosmetic nature and are experiencing significant hair loss possibly due to stress and hormonal issues.

      community Anyone else a non-responder to spiro?

      in Treatments  45 upvotes 4 months ago
      The conversation discusses hair loss treatments, specifically mentioning Spiro, Min, Fin, and RU. It highlights that Spiro is generally for women and can affect men's hormonal balance.

      community Gyno & testoterone level

      in Finasteride  282 upvotes 5 months ago
      Switching from finasteride to dutasteride and back to finasteride led to gynecomastia and fatigue, likely due to hormonal imbalances. Suggested treatments include Tamoxifen, Raloxifene, or low-dose Anastrozole, with a recommendation to test testosterone and estradiol levels.

      community Fin raised my estrogen but also testosterone?

      in Finasteride/Dutasteride  17 upvotes 9 months ago
      A user experienced initial side effects from finasteride, including erectile dysfunction and emotional changes, but later noticed increased muscle mass and assertiveness. Hormonal tests showed elevated estrogen and prolactin levels, which slightly decreased over time; the user plans lifestyle changes to see if they help.

      community Female male-pattern AGA- seeking help

      in Female  1 upvotes 11 months ago
      A female with male-pattern hair loss (AGA) is seeking help after unsuccessful treatments with spironolactone and supplements, and is considering oral minoxidil and finasteride despite concerns about medication side effects. She has ruled out hormonal birth control and PRP/PRFM, and is looking into further medical advice due to abnormal lab results.

      community A Technical Question About Pyrilutamide

      in Research/Science  5 upvotes 1 year ago
      Pyrilutamide is believed to be more effective than RU58841 and 1 mg finasteride in treating hair loss, with no systemic hormonal effects and the potential to block more than 31% of scalp DHT. It may also antagonize scalp testosterone due to its action as an androgen receptor antagonist.

      community any news about DUPA (Diffuse unpatterned alopecia)?

      in Research/Science  11 upvotes 1 year ago
      The conversation discusses diffuse unpatterned alopecia (DUPA) and its possible causes, including sensitivity to DHT, not being androgenic alopecia, being diffuse alopecia areata, or hormonal issues. Treatments mentioned include topical melatonin, Clobetasol Propionate for alopecia areata, and the lack of results from using finasteride, dutasteride, and minoxidil.