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GlossaryHormonal Imbalances (Hormonal Dysregulation)

disruption in hormone levels affecting body functions and processes

Hormonal imbalances occur when there is too much or too little of a hormone in the bloodstream, disrupting the body's normal functions. These imbalances can affect various bodily systems and processes, including metabolism, growth, mood, and reproductive health, and can be caused by factors such as stress, medical conditions, or changes in diet and lifestyle.

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community Opinions on Scalp fibrosis and DHT?

in Research/Science 9 upvotes 2 years ago

The conversation discusses the theory that scalp fibrosis contributes to male pattern baldness (MPB) by increasing DHT concentration, and mentions treatments like Minoxidil. The user seeks opinions on the theory and the effectiveness of scalp massages.

community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 4 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Why I believe PFS is not a "real" condition (and what I believe it is instead)

in Finasteride/Dutasteride 14 upvotes 2 years ago

The post argues that Post-Finasteride Syndrome (PFS) is likely not real and suggests symptoms may be due to mental health issues or the nocebo effect. The conversation includes personal experiences with finasteride, highlighting both positive and negative effects, and emphasizes consulting doctors and using reliable sources for medication.

community Female diffuse hair loss on spiro with irregular periods (photos) + genetic hair loss

in Female 17 upvotes 2 months ago

A 34-year-old woman is experiencing diffuse hair loss and irregular periods, possibly due to long-term spironolactone use. She is considering minoxidil and finasteride for treatment and seeking medical advice for androgenic alopecia and hormonal imbalances.

community 10 months on fin and hairline destroyed.

in Finasteride/Dutasteride 46 upvotes 5 months ago

A user experienced severe hair shedding and hairline recession after 10 months on finasteride. They are considering switching to dutasteride or adding minoxidil.

community Hormonal panel after 1 year of treatment - DHT levels doubled!!

in Finasteride/Dutasteride 8 upvotes 1 year ago

A 27-year-old man shared his hormonal panel results after one year of taking finasteride 1mg/day for hair loss, showing his DHT levels nearly doubled. He reported stabilized hair loss with mild side effects that resolved, and he is considering a hair transplant but is concerned about the increased DHT levels and potential treatment options.

community The Hormonal Profile of MPB/AGA

in Research/Science 9 upvotes 3 years ago

Men with early male pattern baldness (MPB) may have hormonal abnormalities similar to those in women with PCOS. Specific treatments mentioned include Minoxidil, Finasteride, and RU58841.

community Fin completely cured my highly resistant hormonal acne 22m

in Finasteride/Dutasteride 7 upvotes 3 months ago

Finasteride effectively treated hormonal acne for multiple users, including the original poster. Topical treatments like Winlevi are effective but expensive and not always covered by insurance.

community Topical Dutasteride - Non-Hormonal, Side Effect Free 5ARI

in Finasteride/Dutasteride 26 upvotes 4 months ago

The conversation discusses the effectiveness and skepticism around topical dutasteride for hair loss, with mentions of combining it with other treatments like minoxidil and oral medications. Some users doubt its efficacy due to lack of independent studies and potential conflicts of interest.

community Topical Dutasteride - Non-Hormonal, Side Effect Free 5ARI?

in Treatments 450 upvotes 4 months ago

Topical dutasteride is suggested as a low side-effect treatment for hair loss, with a proposed dose of 0.025% 1ml/day. It is considered better than finasteride due to its even inhibition of DHT isoforms and lower systemic absorption.

community Hair Loss Factors in Moms: Analyzing Hormonal Changes, Stress, Genetics, and More

in Treatment 3 upvotes 1 year ago

Hair loss in moms can be caused by hormonal changes, stress, genetics, and nutritional deficiencies. Solutions include hair toppers, Minoxidil, PRP therapy, and a healthy diet with supplements.

community Doctor says i shouldn't take fin because its "hormonal"

in Finasteride/Dutasteride 103 upvotes 4 months ago

A user in Turkey was advised by a dermatologist to avoid finasteride due to its hormonal effects and was prescribed minoxidil, shampoo, and vitamins instead. The user is considering seeking another doctor's opinion or buying finasteride directly from a pharmacy.

community Fin ED is primarily blood flow related, not hormonal as such - a theory

in Research/Science 6 upvotes 3 years ago

The conversation discusses the theory that finasteride-induced erectile dysfunction (ED) is related to blood flow rather than hormonal changes. The user suggests that lowering LDL cholesterol aggressively might improve ED symptoms for those on finasteride.

community Not sure what else to do, can’t use anti-androgens (Baseline Hormonal Bloodwork included) need advice badly

in Update 6 upvotes 3 years ago

User experienced feminizing side effects from finasteride and tried RU, alfatradiol, and finasteride without success. They are now considering treatments like Stemoxydine, Zix, Minoxidil, Dermarolling, Eucapil, and a hair transplant.

community Using WinLevi (Clascoterone) for Seborrheic Dermatitis and Acne

in Treatment 4 upvotes 10 months ago

Winlevi (clascoterone) is discussed as a treatment for hormonal acne and seborrheic dermatitis due to its ability to block DHT and regulate sebum production. The post suggests that Winlevi could offer a novel approach for managing seborrheic dermatitis.

community Anyone else just waiting until the real pyrilutamide and then GT20029?

in Chat 1 year ago

The user is hesitant to use finasteride due to potential hormonal side effects and is waiting for the release of pyrilutamide, a new hair loss treatment. Other users suggest trying finasteride, warning about potential regret if hair loss progresses in the meantime.

community What factors cause more regrowth for MTF people with hormone replacement therapy?

in Transgender 6 upvotes 1 year ago

Hair regrowth in transfems is more effective due to hormonal changes, specifically estrogen, which keeps hair in growth phase longer. Treatments mentioned include anti-androgens, sex hormones, and DHT blockers like finasteride.

community Does Evening primrose oil have a negative effect on a person if they’re taking it alongside finasteride and minoxidil?

in Treatment 2 upvotes 2 years ago

A user is concerned about taking evening primrose oil alongside finasteride and minoxidil due to its potential effects on hormonal balance and DHT inhibition. They seek advice on whether to continue the supplement or if their worries are unfounded.

community Hair loss 30F - thoughts on red light therapy vs min/fin?

in Female 6 upvotes 2 months ago

The conversation discusses hair loss treatments for a 30-year-old female, comparing red light therapy with minoxidil and finasteride. Concerns about hormonal impact and potential pregnancy are raised, with suggestions to consider spironolactone and microneedling, while emphasizing the importance of consulting a dermatologist.

community Feeling energyless and think my 2.5mg dut per day might be causing it

in Research/Science 20 upvotes 3 months ago

Taking 2.5mg of dutasteride daily can cause feelings of low energy, ambition, and motivation, likely due to hormonal imbalances. Many users suggest lowering the dose to 0.5mg to alleviate these side effects.

community Ru58841 for a female w male pattern baldness

in General 166 upvotes 4 months ago

A user is considering using RU58841 for female pattern baldness and is also planning to use Minoxidil. They are hesitant to ask their doctor for spironolactone due to its cosmetic nature and are experiencing significant hair loss possibly due to stress and hormonal issues.

community 2 Months on Minoxidil 5% and Dermarolling - thoughts on progress/potential?

in Journals / Progress Pictures 107 upvotes 4 months ago

A 34-year-old male used Minoxidil 5% and dermarolling for 2 months, seeing significant hair regrowth. He avoided finasteride due to concerns about hormonal effects.

community 2 Months on Minoxidil 5% and Dermarolling. Is this good progress?

in Is this regrowth? 76 upvotes 4 months ago

A user shared their 2-month progress using Minoxidil 5% and dermarolling for hair regrowth, showing positive results. Other users suggested adding finasteride to maintain gains, but the original poster prefers not to use it due to hormonal concerns.

community Anyone else a non-responder to spiro?

in Treatments 63 upvotes 5 months ago

The conversation discusses hair loss treatments, specifically mentioning Spiro, Min, Fin, and RU. It highlights that Spiro is generally for women and can affect men's hormonal balance.

community Gyno & testoterone level

in Finasteride 282 upvotes 6 months ago

Switching from finasteride to dutasteride and back to finasteride led to gynecomastia and fatigue, likely due to hormonal imbalances. Suggested treatments include Tamoxifen, Raloxifene, or low-dose Anastrozole, with a recommendation to test testosterone and estradiol levels.

community What if the prescribed amount of minoxidil doesn’t cover your whole “work” area?

in Minoxidil 9 upvotes 9 months ago

A user is concerned about using more minoxidil than prescribed to cover their hair loss area and mentions taking spironolactone pills. Another user advises against men taking oral spironolactone due to significant hormonal effects.

community Fin raised my estrogen but also testosterone?

in Finasteride/Dutasteride 17 upvotes 10 months ago

A user experienced initial side effects from finasteride, including erectile dysfunction and emotional changes, but later noticed increased muscle mass and assertiveness. Hormonal tests showed elevated estrogen and prolactin levels, which slightly decreased over time; the user plans lifestyle changes to see if they help.

community Female male-pattern AGA- seeking help

in Female 1 upvotes 1 year ago

A female with male-pattern hair loss (AGA) is seeking help after unsuccessful treatments with spironolactone and supplements, and is considering oral minoxidil and finasteride despite concerns about medication side effects. She has ruled out hormonal birth control and PRP/PRFM, and is looking into further medical advice due to abnormal lab results.

community A Technical Question About Pyrilutamide

in Research/Science 5 upvotes 1 year ago

Pyrilutamide is believed to be more effective than RU58841 and 1 mg finasteride in treating hair loss, with no systemic hormonal effects and the potential to block more than 31% of scalp DHT. It may also antagonize scalp testosterone due to its action as an androgen receptor antagonist.

community any news about DUPA (Diffuse unpatterned alopecia)?

in Research/Science 9 upvotes 2 years ago

The conversation discusses diffuse unpatterned alopecia (DUPA) and its possible causes, including sensitivity to DHT, not being androgenic alopecia, being diffuse alopecia areata, or hormonal issues. Treatments mentioned include topical melatonin, Clobetasol Propionate for alopecia areata, and the lack of results from using finasteride, dutasteride, and minoxidil.