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      community We should actually be hopeful for these recent new developments

       112 upvotes 1 year ago
      AI advancements, like AlphaFold, are speeding up drug discovery for hair loss, promising more effective treatments. Current options like minoxidil and finasteride have limitations, but new developments could improve solutions in 5-10 years.

      community Ik I’ll get hate but I’ll say it anyway

      in Chat  111 upvotes 1 year ago
      A clean diet, including cutting sugar, gluten, and dairy, improved hair health and reduced shedding for a user on oral minoxidil and finasteride, but reverting to an old diet worsened hair condition. While diet impacts hair health, genetic factors and treatments like topical ketoconazole and hydrocortisone are also important for managing hair loss.

      community Why is dutasteride's volume of distribution so much bigger than finasteride? Is it more lipophilic and crosses barriers better?

       23 upvotes 1 year ago
      Dutasteride has a larger volume of distribution than finasteride due to its lipophilic nature, allowing it to concentrate in hydrophobic areas and making it difficult to excrete. A user experiencing hair loss has been using oral finasteride for 10 months with minimal regrowth and is considering switching to dutasteride or adding oral minoxidil.

      community Creatine made all my high DHT symptoms return

       82 upvotes 1 year ago
      Creatine may increase DHT levels, potentially causing symptoms like acne, oily hair, and hair shedding. Users report mixed experiences, with some avoiding creatine due to hair loss concerns and others seeing no impact.

      community Did somebody of you start to go in the gym during your hairloss fight?

       29 upvotes 2 years ago
      A 19-year-old paused weightlifting due to hair loss concerns, using finasteride to improve hair condition. Others advised continuing gym workouts while using finasteride, as it doesn't harm hair, and emphasized focusing on fitness and confidence.

      community Still receding on dutasteride after 18 months

      in Finasteride/Dutasteride  11 upvotes 1 month ago
      A 21-year-old male has been using dutasteride for 18 months and a topical minoxidil/finasteride solution for 2.5 years, but his hairline continues to recede. He is considering switching back to finasteride, as some users suggest increasing the dutasteride dose or adding other treatments like ketoconazole shampoo.

      community Hair Loss and Its Immense Impact on Appearance

      in Chat  159 upvotes 4 months ago
      Hair loss significantly impacts self-perception and attractiveness, with treatments like finasteride, minoxidil, and hair transplants suggested. The conversation highlights the emotional struggle and societal perceptions tied to hair loss.

      community Is there any progress? (2 months)

       9 upvotes 5 months ago
      The conversation is about a user seeking feedback on hair regrowth progress after two months of using finasteride, minoxidil, ketoconazole shampoo, dermastamping, and iron supplements. Most responses suggest that two months is too early to see significant results and recommend patience, with noticeable changes typically occurring around 4-6 months.

      community Minoxidil and Finastride topical solution 2 months update

      in Minoxidil  6 upvotes 6 months ago
      A 34-year-old woman has been using a topical solution of 5% Minoxidil and 0.1% Finasteride since January 2026 to address hair thinning caused by PCOS and poor nutrition. She reports ongoing hair shedding but has improved her diet with whole foods and supplements.

      community Haïr différence after 1 year dut with alternate days

      in Finasteride/Dutasteride  63 upvotes 9 months ago
      The user experienced hair thickening and regrowth using dutasteride on alternate days, oral minoxidil every third day, and daily hair massages, but is dealing with dandruff and inflammation. They are considering adjusting their minoxidil dosage and have started using ketoconazole shampoo and cupping therapy for additional benefits.

      community Almost 20 Years on Finasteride - AMA

      in Progress Pictures  837 upvotes 1 year ago
      A user successfully halted hair loss using finasteride for 17 years and recently switched to dutasteride for stronger DHT suppression. They experienced no major side effects, maintained a full head of hair, and fathered three children without issues.

      community 6-month finasteride and minoxidil adventure

      in Progress Pictures  195 upvotes 1 year ago
      The user experienced increased self-confidence and interest from women after using 1.25mg finasteride and twice-daily minoxidil foam for six months, despite minor side effects like forgetfulness and slight gynecomastia. The user also noted no additional hair growth elsewhere except for using minoxidil on their mustache.

      community Ketoconazole shampoo stopping shed

      in Ketoconazole  11 upvotes 1 year ago
      The user experienced reduced hair shedding with Ketoconazole shampoo, suggesting it may help with scalp inflammation and hair health. They also use Minoxidil and Finasteride, and suspect food intolerance and stress contribute to their hair issues.

      community How much do you guys think diet and sleep affects results?

       34 upvotes 3 years ago
      The conversation discusses whether lifestyle factors like diet and sleep affect hair growth in people with reversible hair loss. Some believe these factors, along with treatments like minoxidil, finasteride, and RU58841, can improve hair health, while others argue hair loss is mostly determined by genetics and DHT sensitivity.

      community Four Year Progress Update Photos

       536 upvotes 3 weeks ago
      A user shared their four-year hair regrowth progress using a regimen of Kirkland Minoxidil foam, Dutasteride, a derma roller, Nizoral shampoo, multivitamins, and a healthy lifestyle. They started seeing significant results after a year with no side effects reported.

      community We already know how to permanently fix hair loss. The science is done. The only thing missing is the funding to run one experiment.

      in Technology  613 upvotes 4 months ago
      A permanent hair loss solution could involve reprogramming hair follicles to resist DHT using mRNA and siRNA. However, high costs, safety concerns, and the pharmaceutical industry's preference for ongoing treatments over one-time cures are major obstacles, with finasteride and minoxidil remaining standard treatments.

      community Why hasn’t anyone made a "DHT sponge" biologic yet???

      in Research/Science  45 upvotes 9 months ago
      The conversation discusses the potential for developing a biologic "DHT sponge" to neutralize DHT in the bloodstream as a treatment for hair loss, suggesting it could be more targeted and have fewer side effects than current treatments like finasteride and dutasteride. Concerns include the complexity, cost, and potential side effects of such a treatment, as well as skepticism about its feasibility and market interest.

      community 1.5 year on finasteride,microneedling,and minoxidil.Nothing helps its getting even worse.Is it possible that finasteride doesnt work on everybody? 19m

       13 upvotes 1 year ago
      The user has been using topical finasteride, minoxidil, microneedling, and various supplements for hair loss without success, and is advised to reduce microneedling frequency and consider oral finasteride or dutasteride. It is noted that finasteride may not work for everyone, and some users suggest checking hormone levels and deficiencies.

      community Microneedling to maintain results from min

      in Microneedling  7 upvotes 1 year ago
      Microneedling alone is not effective in maintaining minoxidil results for hair growth. Combining microneedling with minoxidil and finasteride may enhance results, but microneedling by itself is not a reliable treatment.

      community Lion Mane Part 2: Microneedling with Topicals, beneficial compounds, maybe?

       1 upvotes 2 years ago
      The conversation discusses microneedling techniques and the use of Minoxidil, copper peptides, EGF, FGF, ceramides, and hydration serums to enhance hair growth. It explores optimizing scalp conditions and the potential benefits of various compounds in conjunction with microneedling.

      community I've been taking medicines for my hair loss at 18? Read description

       2 upvotes 8 years ago
      A 22-year-old from India is using finasteride, Trichoton AT, and a multivitamin to address hair loss, noticing some regrowth. They are concerned about weight gain and the psychological effects of masturbation but find no strong evidence linking it to hair loss.

      community 19 months Topical Min/Fin - 7 months HRT

       1072 upvotes 3 months ago
      The user experienced significant hair regrowth and fullness after starting hormone replacement therapy (HRT) with sublingual estrogen and spironolactone, in addition to using a topical solution of minoxidil, finasteride, ketoconazole, and biotin. They noted initial shedding phases but emphasized that shedding is a sign of future growth.