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      community Topical finasteride might be a lie

      in Research/Science 1 year ago
      The conversation discusses doubts about the effectiveness of topical finasteride for hair loss, suggesting that DHT could be produced elsewhere in the body and affect the scalp. It proposes that androgen receptor antagonists like spironolactone and clascoterone might be more effective as they could prevent this potential bypass mechanism.

      community Sharing my (relatively short) Success Story

      in Progress Pictures  77 upvotes 1 year ago
      A user named "paulsac11" shares their success story of treating hair loss. They started with topical minoxidil, then switched to oral minoxidil and dutasteride. They also used a shampoo and conditioner from Keeps. After eight months of treatment, they have seen significant improvement in their hairline.

      community How effective is spironolactone?

      in Transgender  6 upvotes 2 years ago
      A 21-year-old MTF individual is experiencing rapid hair thinning and is currently on estradiol valerate. They are inquiring about the effectiveness of spironolactone for hair loss, despite being aware of its serious side effects.

      community Results so far on Finasteride and biotin

      in Progress Pictures  145 upvotes 2 years ago
      The conversation is about someone experiencing significant hair regrowth after 23 days on Finasteride and Biotin, with others suggesting additional treatments like Minoxidil and microneedling. Some doubt the speed of hair growth, while others believe Biotin isn't contributing to the results.

      community Please stop looking for a natural way to stop your hairloss

      in Chat  247 upvotes 2 years ago
      There is no natural way to stop hair loss; pharmaceuticals like minoxidil, finasteride, and RU58841 are the only effective treatments. Some users report success with minoxidil and microneedling, while others discuss the side effects of finasteride.

      community [25, F] [RANT] Shedding since March 2020. This just isn’t fair.

      in Female  42 upvotes 3 years ago
      User "missbloombastic" has been experiencing hair loss since 2016 and tried min, fin, multivitamins, and spiro with mixed results. Another user shares their struggle with hair loss and its impact on self-esteem, while a third user suggests checking blood tests and confirming the cause of hair loss.

      community Am I balding? Should I just shave it off?(M86)

      in Satire  116 upvotes 5 months ago
      A user humorously questions if they should shave their head due to hair loss, mentioning Ronald Reagan's impressive hair genetics. Replies include jokes and comments about jealousy and distrust towards older individuals with full heads of hair.

      community Don't give up! 9 months on Minoxidil

      in Progress Pictures  392 upvotes 6 months ago
      A trans man shared progress pictures showing significant hair regrowth after 9 months on oral Minoxidil and 1.5 years on finasteride. He encourages others to stick with their treatments despite initial setbacks.

      community Started Finasteride almost three months ago and I'm upset

      in Update  153 upvotes 8 months ago
      A user started taking finasteride three months ago to treat hair loss and unexpectedly cleared their acne, which they had been struggling with since age 12. The conversation includes others sharing their experiences with finasteride, its effects on acne and hair loss, and mentions a related treatment, clascoterone, for acne and hair loss.

      community Well here I am 3-4 years later.

      in Update  56 upvotes 9 months ago
      The conversation is about someone who has been taking finasteride for hair loss without success, considering switching to dutasteride or giving up treatment. Suggestions include trying dutasteride, microneedling, infrared therapy, multivitamins, and high-concentration topical solutions combining finasteride and dutasteride.

      community Finasteride won’t make all your problems go away

      in Finasteride/Dutasteride  323 upvotes 11 months ago
      A user shared that while finasteride improved their hair, it didn't solve all their insecurities, suggesting that self-acceptance is key. Others in the conversation expressed varying opinions, with some feeling that finasteride significantly boosted their confidence and quality of life, while others acknowledged it as a solution to hair loss but not a cure-all for other personal issues.

      community Study shows further evidence that finasteride and dutasteride take 12-18 months or more to show significant results. Do NOT give up early

      in Finasteride/Dutasteride  247 upvotes 1 year ago
      The conversation discusses the effectiveness of finasteride and dutasteride in treating hair loss, emphasizing that significant results often take 12-18 months or more. Dutasteride is generally considered superior, with similar or fewer side effects than finasteride, but patience is required for noticeable improvement.

      community Kintor’s GT20029 Phase 1 success

      in Update  73 upvotes 1 year ago
      Kintor's GT20029, a treatment for hair loss, has completed Phase 1 successfully, showing promise as an androgen receptor degrader that could potentially regrow hair. It is considered more effective than Pyrilutamide, with infrequent dosing and minimal systemic absorption.

      community Dutasteride 4.5 months really struggling what should I do

      in Finasteride/Dutasteride  18 upvotes 1 week ago
      The user has been on dutasteride for 4.5 months after switching from finasteride due to hair thinning, and is experiencing significant hair loss despite also using minoxidil and microneedling. Many responses suggest that dutasteride takes time to show results, often requiring patience for up to a year or more, and recommend not stopping finasteride abruptly to avoid shedding.

      community Bile Acid-Mediated DHT Dysregulation Hypothesis

      in Research/Science  13 upvotes 2 weeks ago
      Elevated bile acids can inhibit the enzyme AKR1C2, leading to increased DHT levels, which may accelerate hair loss in those predisposed to androgenetic alopecia. Treatments mentioned include topical minoxidil and finasteride.

      community Verteporfin and Microneedling

      in Treatments 5 months ago
      Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.

      community Just started my third month of fin min

      in Treatment  148 upvotes 9 months ago
      A user, aged 32, is treating hair loss with oral finasteride, topical minoxidil, Vitamin D3, and magnesium. They shave their head, condition daily, and wash their hair every three weeks.

      community Hormonal panel after 1 year of treatment - DHT levels doubled!!

      in Finasteride/Dutasteride  7 upvotes 11 months ago
      A 27-year-old man shared his hormonal panel results after one year of taking finasteride 1mg/day for hair loss, showing his DHT levels nearly doubled. He reported stabilized hair loss with mild side effects that resolved, and he is considering a hair transplant but is concerned about the increased DHT levels and potential treatment options.

      community 4 years of dutasteride monotherapy

      in Progress Pictures  191 upvotes 1 year ago
      The conclusion of the conversation is that the user experienced noticeable regrowth of hair after using dutasteride as a single treatment for about 1.5 years. No before photos were available.