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      community Kintor’s GT20029 Phase 1 success

      in Update  73 upvotes 1 year ago
      Kintor's GT20029, a treatment for hair loss, has completed Phase 1 successfully, showing promise as an androgen receptor degrader that could potentially regrow hair. It is considered more effective than Pyrilutamide, with infrequent dosing and minimal systemic absorption.

      community Pyrilutamide real life results?

      in Research/Science  15 upvotes 2 years ago
      The results of using Pyrilutamide, a hair loss treatment available on the gray market, and other treatments such as Minoxidil, Finasteride and RU58841.

      community 4 years on finasteride and Minoxidil with great success. Ask me stuff!

      in Progress Pictures  953 upvotes 2 years ago
      . ummwhatsure: No it doesn't. I started losing my hair around 27/28. This user has had great success with a combination of finasteride and Minoxidil, taking 1 milligram of finasteride per day and applying Minoxidil twice daily for 4 years, starting when they were 31. They experienced some shedding in the first two years, but now have thicker, fuller hair than before.

      community My experience with Pyrilutamide

      in Update  43 upvotes 2 years ago
      Two different experiences of using Pyrilutamide, a hair loss treatment, which caused headaches that took around a week to subside in both cases. Other users offered insight into their own experiences with the treatment or suggested alternate treatments such as RU58841 and Minoxidil.

      community Ingest topical minoxidil by mouth ?

      in Minoxidil  6 upvotes 2 years ago
      A user questions if ingesting topical minoxidil could be an alternative to oral minoxidil for hair loss. Another user reports success with this method, noting they saw results and experienced no adverse effects.

      community The theory that explains everything. Please help me make this big!

      in Research/Science  2447 upvotes 3 years ago
      The post and conversation are about the role of the enzyme 3alpha-hydroxysteroid reductase in hair loss and the potential of compounds like procyanidin B2 and sulforaphane to boost its activity for hair regrowth. Further research is needed to develop effective treatments based on this theory.

      community Thinking about my making own CB-03-01 (Breezula). Thoughts?

      in Treatment  6 upvotes 3 years ago
      The user experienced side effects with both oral and topical finasteride and is considering making their own hair loss treatment using CB-03-01 (Breezula) mixed with minoxidil due to fewer reported side effects. They plan to use a lower concentration than what was used in trials.

      community [21 M] - 2.5 Year Progress Report

       11 upvotes 9 years ago
      A 21-year-old man shared his 2.5-year experience with hair loss treatments, including 1mg Propecia (finasteride) nightly, 12.5% Minoxidil once daily, 2% Nizoral shampoo 2-4 times a week, and later 5% Minoxidil once daily. He experienced minor side effects like watery semen and itchy scalp, and while he's seen fluctuations in hair growth, he's generally happy with the results and is considering experimental treatments like CB-03-01 and RU58841.

      community Creatine made all my high DHT symptoms return

      in Research/Science  78 upvotes 3 weeks ago
      Creatine may increase DHT levels, potentially causing symptoms like acne, oily hair, and hair shedding. Users report mixed experiences, with some avoiding creatine due to hair loss concerns and others seeing no impact.

      community 500mg pill of dutesteride ? Will I become Jesus him self ?

      in Satire  53 upvotes 1 month ago
      The conversation humorously discusses the exaggerated effects of taking a 500mg pill of dutasteride, with users joking about extreme side effects like excessive hair growth and loss of sensation. It also mentions personal experiences with finasteride and the potential high bioavailability of dutasteride in liquid form.

      community Treatment isn't working? Stay the course.

      in Treatment  1 upvotes 1 month ago
      The user tried finasteride for a year without success, then switched to dutasteride and oral minoxidil for 10 months, still experiencing hair loss. Adding RU58841 and topical minoxidil seemed to improve their condition, with new hair growth observed.

      community One year on fin + dut + 2.5 oral min, is it over for me

      in Progress Pictures  8 upvotes 3 months ago
      The user has been using finasteride daily since 2020, dutasteride twice weekly since September, 2.5 mg oral minoxidil daily, microneedling monthly, and ketoconazole semi-often. They are feeling lost about their hair loss progress after one year on this regimen.

      community Which Pyrilutamide has worked the best for you ?

      in Treatment  4 upvotes 4 months ago
      The user is currently using Minoxidil with melatonin, rosemary, peppermint, azelaic acid, and RU58841 for hair loss and plans to add fluridil and Pyrilutamide. They seek advice on the best Pyrilutamide source, noting Actifolic worked briefly.

      community My mum is mad annoying about Fin.

      in Chat  245 upvotes 6 months ago
      A 25-year-old man discusses his struggles with his mother's opposition to his use of Finasteride for hair loss treatment, despite it improving his condition and self-control after a hair transplant. He expresses frustration over her blaming the medication for various issues and the stress caused by her insistence to stop taking it.

      community Spironolactone for 11 years, finasteride for almost 5 years, started oral minoxidil in November 😢 ended oral contraceptive in Dec.

      in Progress Pictures  224 upvotes 7 months ago
      A user shared their 11-year experience with spironolactone and nearly 5 years with finasteride for hair loss, recently adding oral minoxidil and stopping birth control. Various treatments were discussed, including organic options, checking for underlying health issues, considering dutasteride, and the potential role of progesterone in hair loss.

      community Why isn’t oral minoxidil enough for me?

      in Minoxidil  7 upvotes 8 months ago
      A user takes 5mg oral minoxidil, oral dutasteride, topical tretinoin, stemoxydine, topical minoxidil, and uses dermarolling for hair loss but sees less impressive, patchy regrowth compared to others. Another person suggests some online results may be enhanced with hair fibers, not just medication.

      community Is it ok to use minoxidil and other topicals simultaneously?

      in Minoxidil  2 upvotes 8 months ago
      The conversation is about whether it's safe to use minoxidil with a mix of stemoxydine, RU58841, alfatradiol, and tretinoin at the same time for hair loss treatment. Concerns were raised about the absorption and effectiveness when these treatments are applied together.

      community Approximation of Scalp DHT Suppression Between 0.05 mg to 2.5 mg

      in Research/Science  63 upvotes 9 months ago
      The conversation discusses the effectiveness of various doses of Dutasteride in reducing scalp DHT and its impact on hair count. Users shared personal experiences with hair loss treatments, including Dutasteride, Finasteride, and Minoxidil, with one reporting significant hair loss reduction using a combination of oral Dutasteride and topical Minoxidil and Finasteride.

      community PYRILUTAMIDE PHASE 3 RESULTS : No statistical significance

      in Research/Science  122 upvotes 11 months ago
      The phase 3 trial results for Pyrilutamide showed no significant difference from the control treatment in increasing hair count, leading to the company halting its development. Users discussed their disappointment and skepticism about hair loss treatments, with some mentioning other treatments like Minoxidil, Finasteride, and RU58841.

      community Dutasteride 6 months - Should I quit or wait more?

      in Finasteride/Dutasteride  11 upvotes 1 year ago
      The user has been on dutasteride for 6 months, experiencing initial hair health but then shedding and brittle hair, with no improvement. They use minoxidil, ketoconazole, dutasteride, and vitamin D, and are questioning whether to continue treatment despite no results.

      community It's over. Hairline has fallen. Millions must shave.

      in Update  467 upvotes 1 year ago
      The conclusion of the conversation is that the user has tried various medications and treatments for hair loss, including minoxidil, finasteride, microneedling, and nizoral shampoo, but has not seen any progress. They have decided to shave their head. Other users suggest options such as hair transplants, RU58841, hair units, and scalp micropigmentation.