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      community Nearly 3 years in and I'm on a mega growth spurt. Don't lose heart.

      in Chat  63 upvotes 9 months ago
      The user experienced subtle hair growth improvements using finasteride, dutasteride, and minoxidil over nearly three years, with notable progress at the temples. The front hairline shows quicker regrowth cycles, but the vertex and crown remain unchanged.

      community Expectations control for SCUBE3

      in Research/Science  22 upvotes 11 months ago
      SCUBE3, a protein linked to hair growth in moles, was discovered over 25 years ago and is being developed by Amplifica for potential hair loss treatment. Concerns exist about SCUBE3's association with cancer, as it is a protein that promotes cell growth, which could potentially trigger cancer development if used for hair growth therapy.

      community Does low HGH leading to hairloss?

      in Research/Science  11 upvotes 1 year ago
      The user experiencing diffuse hair loss is using various treatments including RU58841, finasteride, minoxidil with tretinoin, anti-hair loss shampoo, and microneedling, and is considering adding peptides TB500, BPC157, and GHK-Cu. They have low growth hormone levels and are questioning its impact on hair loss, while another user suggests androgenic alopecia and androgens are likely the main cause of hair loss.

      community Brainstorming: upping your dermarolling game

      in Research/Science  6 upvotes 1 year ago
      The conversation is about enhancing dermarolling for hair loss by using topical peptides like tb-500 or GHK-Cu to aid in healing and hair growth, and whether anyone has experienced significant results from this method.

      community Updates about KX-826 & GT20029

      in Research/Science  16 upvotes 1 year ago
      The conversation discusses potential advancements in two hair loss drugs, KX-826 and GT20029, and the interest in whether transitioning from oral finasteride to these drugs would maintain hair growth. One reply expresses skepticism about the compounds' representation.

      community Hair loss treatments rated (by gpt-4)

      in Research/Science  252 upvotes 1 year ago
      Rating treatments for hair loss, with the help of GPT-4, according to efficacy, evidence and tolerability; a combination of chemicals from research papers, custom compounds, and some suggestions from other users were included.

      community About the CBD regrowth study : just a few remarks

      in Research/Science  167 upvotes 3 years ago
      CBD in an emu and lanolin oil preparation showed a 100% increase in hair growth, but the effectiveness may partly come from the oils. Users discussed proper CBD dosage, preparation methods, and skepticism about the study's quality.

      community Why microneedling can ruin a hair transplant

      in Microneedling  14 upvotes 1 week ago
      Microneedling's effectiveness for hair growth is debated, with some suggesting it enhances minoxidil absorption, but evidence is inconclusive. Concerns exist about its impact on hair transplants, and opinions vary on its use with other treatments like RU58841 and stemoxydine.

      community New Study For LLLT > Minoxidil

      in Research/Science  7 upvotes 10 months ago
      LLLT (low-level laser therapy) is as effective or better than traditional minoxidil treatment for hair growth, with fewer side effects and improved long-term compliance due to milder adverse effects. Studies show LLLT increases hair density more than minoxidil, but drawbacks include the initial cost and the need for long-term use to see results.

      community Fibrosing alopecia in a pattern distribution

      in Research/Science  14 upvotes 11 months ago
      A user has been experiencing hair loss for 4 years, with treatments like minoxidil, finasteride, and various supplements proving ineffective. They were diagnosed with fibrosing alopecia in a pattern distribution, a condition that may require a combination of anti-inflammatory and hair growth treatments.

      community Is there a consensus on a "best conditioner" to use?

      in Research/Science  12 upvotes 1 year ago
      The conversation is about finding the best conditioner for hair loss, with a mention that Ketoconazole shampoo is recommended for reversing hair loss. Users suggest that most "hair growth" conditioners are ineffective and discuss using anti-dandruff conditioners with piroctone olamine.

      community Growth journey stated in January

      in Progress Pictures  467 upvotes 1 year ago
      User shared hair growth progress since January using treatments like minoxidil, nizoral shampoo, rosemary oil, biotin oil, and derma roller. Others suggested solutions for minoxidil side effects and recommended adding a multivitamin.

      community No side effects on pyrilutamide / KX-826 so far

      in Research/Science  204 upvotes 3 years ago
      User TopBack56 and friends tried pyrilutamide (KX-826) for hair loss without experiencing negative side effects. They observed fine vellus hairs but no thick hair growth yet, and plan to add GT20029 to their regime after safety trials.

      community Insane Idea: Cyperus Rotundus Oil?

      in Research/Science  9 upvotes 4 months ago
      Cyperus rotundus oil is suggested as a natural treatment for androgenic alopecia, potentially inhibiting hair growth without affecting testosterone levels. The conversation questions its effectiveness and safety for scalp use.

      community Oxytocin, empathy, hair, and cinnamon

      in General  138 upvotes 6 months ago
      Low oxytocin levels in hair are linked to reduced empathy and may affect hair growth. Cinnamic acid can promote hair growth by activating oxytocin receptors.

      community ET-02 Now Recruiting in Texas for Phase 1

      in Research/Science  20 upvotes 8 months ago
      Eirion Therapeutics is recruiting for phase 1 of ET-02 in Texas, which showed promising hair growth results in non-clinical studies. ET-02 demonstrated significantly more hair growth compared to Minoxidil.

      community Fun thought experiment about halting hair loss permamently

      in Research/Science  58 upvotes 9 months ago
      A user proposed genetically engineering scalp stem cells to stop androgen receptors from causing hair loss. Others discussed the feasibility, existing research, and potential issues with this approach, including targeting the correct cells and unintended effects.

      community Is anyone on topical NMN 1% here?

      in Research/Science  1 upvotes 10 months ago
      A user added 1% NMN to their 5% minoxidil mix for hair loss, which also includes melatonin, ginkgo, nettle root, and plans to add caffeine. They are asking if anyone has tried topical NMN for hair growth.

      community Any New Findings or Interesting Research?

      in Research/Science  24 upvotes 1 year ago
      The conversation is about seeking new research on hair loss treatments beyond the commonly known ones like Minoxidil and Finasteride. Additions to the list of treatments include topical caffeine, alfatradiol, fluridil, stemoxydine, and upcoming treatments like TDM-105795 and verteporfin.

      community [Research/Science] What's the General Consensus On Pyrilutamide So Far?

      in Research/Science  8 upvotes 2 years ago
      Pyrilutamide is considered to work for hair loss but less effectively than expected, similar to RU58841, and may cause side effects like chest tightness and sexual issues. It's unclear if it's suitable for diffuse thinners, and one user cannot use minoxidil or finasteride due to side effects and personal circumstances.