Minoxidil gains are not permanent without continued use, even with DHT suppression. Combining treatments like Dutasteride, Finasteride, and RU58841 may help maintain hair, but stopping Minoxidil typically results in hair loss.
A user shared a positive 5-year experience with oral finasteride and minoxidil for hair loss, noting improvement and stability. Others in the conversation also reported positive results with these treatments.
The conversation discusses a new hairgrowth treatment that showed a 14 hairs/cm2 increase in a trial, with mixed opinions on its effectiveness and potential cost. Some users are hopeful about combining it with existing treatments like oral minoxidil for better results.
PP405 is a new hairgrowth stimulant different from Minoxidil, currently in phase 2 trials. Users discuss its potential, safety concerns, and the long wait before it might be available.
The user is experiencing hair loss and is considering using finasteride again, along with ketoconazole shampoo and curl cream, to manage their long hair. They are concerned about the appearance of new hairgrowth and the potential shedding phase from minoxidil.
GT20029 showed significant hairgrowth and safety in phase II trials, with no adverse sexual events. Users are hopeful but concerned about future costs and systemic effects.
Eirion Therapeutics is recruiting for phase 1 of ET-02 in Texas, which showed promising hairgrowth results in non-clinical studies. ET-02 demonstrated significantly more hairgrowth compared to Minoxidil.
The GT20029 tincture, a topical androgen receptor degrader, showed significant hairgrowth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.
The conversation discusses the removal of Breezula phase II 12-month results by Cassiopea and the search for the original data. Concerns were raised about potential negative long-term effects on hairgrowth, such as androgen receptor upregulation.
The user is using Dutasteride, Minoxidil, microneedling, RU58841, and tretinoin for hair loss. They are experiencing shedding but notice new hairgrowth and are curious about the timing of future shedding phases.
Hair loss treatments like GT20029, pyrilutamide, and Follica show promise in 2022. Phase 1 and 2 trials are underway, and new hairgrowth studies have been published.
User is pleased with hairgrowth results after nearly a year of using Minoxidil and finasteride, despite experiencing shedding phases. They noticed thicker hair regrowth and saw visible improvement around the 4th or 5th month.
JW0061 shows superior hairgrowth results compared to existing treatments, with significant increases in hair follicles. The Wnt/β-catenin pathway is crucial for hairgrowth, and JW0061 activates this pathway effectively.
The conversation discusses whether sunlight exposure affects hairgrowth or loss, with mixed anecdotes and theories but no clear consensus. Some suggest moderate sunlight can benefit hair by providing vitamin D, while others doubt its effectiveness compared to treatments like Minoxidil or finasteride.
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In this conversation, users discussed the risks of drinking topical minoxidil and suggested alternative treatments such as obtaining a prescription for oral minoxidil or finasteride.
The conversation is about using vitamin C and Magnesium L-Threonate for hairgrowth by reducing DHT binding to dermal papilla cells. The original post about vitamin C's pH levels and sebum control was possibly removed by a moderator.
Sildenafil (Viagra) shows potential for hairgrowth by enhancing dermal papilla cell proliferation and stimulating perifollicular vessel formation. Users discuss the possibility of using Cialis (tadalafil) similarly, noting its benefits and side effects.
The conversation is about hair loss treatments, specifically discussing the effectiveness of Red Ginseng Extract in promoting hairgrowth. Other treatments mentioned include Minoxidil, finasteride, and RU58841.
A user is participating in a phase 3 trial for Clascoterone, a topical acne medication that may stimulate hairgrowth, and will share results after 6 months. They will have a section of their hair shaved and marked with a tattoo for the study.
Finasteride, Minoxidil, Bioneer CosmeRNA, Technoderma, Kintor, Hope, Breezula, and Follicum treatments showed increases in hair count, with Technoderma showing the highest increase at 24.3 hairs/cm². Amplifica has not yet published results.
A user who underwent a hair transplant in their twenties and are now discussing the best treatments for long-term management of hair loss, such as finasteride and Minoxidil, as well as potential alternative treatment options like RU58841.
The user started hair loss treatment on June 26th using 1.25mg finasteride, 1ml 5% minoxidil twice a day, derma rolling every 1.5 weeks, and 2% ketoconazole foam twice a week. They experienced significant hairgrowth in the first four months, with thicker hair and improved hairline, but had a rough shedding phase in November.
Pyrilutamide, a potential hair loss treatment that has been tested in Phase 2 trials and may be available for purchase through a group buy in June. It is purported to have similar effects on hairgrowth as Dutasteride.
Oral biotin combined with topical minoxidil may increase hairgrowth rate, though the study was limited to healthy subjects and did not measure hair density. Some users report personal benefits from biotin, such as faster nail growth and healthier hair, but concerns about acne and study quality were also mentioned.
A user shared their 7-month progress using oral minoxidil (2.5mg) and recently started finasteride (1mg) daily, reporting significant hair improvement without side effects. They noticed thicker beard growth and some hair thickening at the crown, with no shedding phase yet.
The conversation is about whether treatments like finasteride, dutasteride, and minoxidil can make single hair follicles produce multiple hairs again. The user is curious if these medications can thicken hair and prolong the growthphase.
The conclusion of the conversation is that experiencing shedding while using finasteride and minoxidil is a common occurrence, and it is likely a part of the hairgrowth cycle. Many users have reported regrowth and improvement in their hair density after the shedding phase.
The user shared a 1.4-year hairgrowth journey using minoxidil and recently added micro-needling and finasteride, which significantly improved their hair. They also mentioned taking consistent photos for comparison and dermarolling once a week with a 1.5 mm needle.
The conversation discusses the failure of Phase 3 trials for the hair loss treatment KX-826, with no significant difference found between the drug and placebo. Some users express disappointment and skepticism, while others discuss alternative treatments like Minoxidil, finasteride, and RU58841.