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      community (Serious) News and discussion on potential treatments

      in Treatment  27 upvotes 2 weeks ago
      Current hair loss treatments include finasteride, dutasteride, minoxidil, and derma rolling. New treatments like TDM-105795, GT20029, and others show promise but require more testing and time before approval.

      community Insane MTF recovery 18 months blocking androgens

      in Progress Pictures  145 upvotes 1 year ago
      Hair loss recovery using estrogen and anti-androgen treatment for 18 months showed significant improvement. However, results vary and alternative treatments like RU58841 and Dutasteride may work without systemic feminization.

      community The 'DHT itch' is real - notes from a casual bodybuilder

      in Chat  115 upvotes 2 months ago
      The "DHT itch" is real and likely due to inflammation at the hair follicle, exacerbated by increased testosterone or androgens. Treatments mentioned include dutasteride, minoxidil, finasteride, and various topical solutions.

      community TDM-105795 phase 2 results are in!

      in Research/Science  28 upvotes 9 months ago
      TDM-105795 showed promising hair growth results, with higher efficacy than placebo and minimal side effects. It activates dormant hair follicle stem cells and may maintain gains without immediate loss, unlike minoxidil.

      community Best Microneedle Lengths To Stimulate Stem Cells

      in Microneedling  18 upvotes 1 year ago
      Microneedling with needle lengths of 1.5mm to 2.5mm to stimulate hair follicle stem cells for potential hair growth. Using needles longer than 2.5mm is not recommended due to risk of puncturing veins in the scalp. A dermastamp is suggested over a roller.

      community Pre and Post Dermarolling Routine?

      in Microneedling  18 upvotes 4 years ago
      The conversation is about a hair loss treatment routine involving dermarolling, finasteride, minoxidil, and natural oils. Suggestions include using shorter needles for better absorption of treatments and longer needles less frequently for hair follicle regeneration.

      community What else is good. Besides the big 3.

      in Chat  36 upvotes 1 month ago
      Key treatments for hair preservation include minoxidil, finasteride/dutasteride, and microneedling, with additional options like specific shampoos, oils, biotin, zinc, tretinoin, clascoterone, and low-level laser therapy. Maintaining a healthy lifestyle, reducing stress, and addressing nutrient deficiencies can also support hair health.

      community 3 Months Fin/Min/Microneedling

      in Progress Pictures  250 upvotes 7 months ago
      The user shared a 3-month progress update on hair loss treatment using finasteride (1 mg), minoxidil (5% once or twice daily), and microneedling (1.5mm every 2 weeks) with no side effects. Commenters are impressed, discussing hair follicle revival and the user's method, noting the hair appears darker.

      community 3yr Fin/Dut/Niz NW3+ —> NW1.5 Pictures with Writeup

      in Progress Pictures  32 upvotes 4 years ago
      A user improved their hair loss from NW3+ to NW1.5 over three years using a regimen of dutasteride, finasteride, Nizoral, biotin, and collagen. They experienced some side effects and adjusted dosages over time, and noted additional benefits like better skin and muscle gain.

      community Anyone else realize how many younger guys are balding?

      in Chat  262 upvotes 1 month ago
      Many younger men are experiencing hair loss due to genetics, diet, stress, and lifestyle changes. Treatments like finasteride and minoxidil are mentioned, with some users noting improvements.

      community A hill on which I will die: The DHT itch absolutely exists

      in Research/Science  209 upvotes 6 months ago
      The DHT itch is linked to hair loss and persists despite finasteride use; switching to dutasteride helped alleviate the itch and promoted regrowth. Some users suggest seborrheic dermatitis as a cause and recommend treatments like medicated shampoos, vitamin D, and minoxidil.

      community [Research/Science] What's the General Consensus On Pyrilutamide So Far?

      in Research/Science  8 upvotes 1 year ago
      Pyrilutamide is considered to work for hair loss but less effectively than expected, similar to RU58841, and may cause side effects like chest tightness and sexual issues. It's unclear if it's suitable for diffuse thinners, and one user cannot use minoxidil or finasteride due to side effects and personal circumstances.

      community Anyone else crying themselves to sleep because of the pyrilutamide fail?

      in Technology  41 upvotes 11 months ago
      The conversation is about disappointment with pyrilutamide's performance as a hair loss treatment, with some users expressing interest in other treatments like Verteporfin, GT20029, and RU58841, while others suggest sticking with established treatments like finasteride or dutasteride.

      community 11 months on 5mg oral minoxidil

      in Progress Pictures  972 upvotes 1 year ago
      A user's 11-month progress using 5mg oral minoxidil for hair loss. The user reported significant hair regrowth, including on the beard and eyebrows, and experienced minor side effects like headaches and increased body hair.

      community This sub is very toxic towards people who don’t blindly follow the fin mafia

      in Treatment  226 upvotes 1 year ago
      The conversation criticizes the negative attitude towards those concerned about side effects from hair loss treatments like finasteride and minoxidil, or who prefer natural remedies. Specific treatments discussed include finasteride, minoxidil, rosemary oil, and RU58841, with an agreement that finasteride and minoxidil are proven effective.

      community BREEZULA COVID UPDATE: Filing for Special Protocol Assessment with FDA

      in Research/Science  64 upvotes 4 years ago
      The conversation discusses the progress of Clascoterone (Breezula) for hair loss treatment, noting that COVID-19 delayed female trials by three months but Phase III trials for males are proceeding with a Special Protocol Assessment filed with the FDA. Users express hope for Breezula as an alternative to existing treatments like finasteride and minoxidil, despite concerns about its potential high cost.

      community Creatine made all my high DHT symptoms return

      in Research/Science  78 upvotes 3 weeks ago
      Creatine may increase DHT levels, potentially causing symptoms like acne, oily hair, and hair shedding. Users report mixed experiences, with some avoiding creatine due to hair loss concerns and others seeing no impact.

      community (Serious) Updates and discussion, new treatments in development

      in Treatment  7 upvotes 5 months ago
      Finasteride, minoxidil, and derma rolling are currently the best treatments for hair loss. New treatments like TDM-105795, GT20029, PP405, HMI 115, Tsuji, Scube 3, RU, JW0061, Topilutamide, and verteporfin show promise but have uncertain timelines.

      community PYRILUTAMIDE PHASE 3 RESULTS : No statistical significance

      in Research/Science  122 upvotes 11 months ago
      The phase 3 trial results for Pyrilutamide showed no significant difference from the control treatment in increasing hair count, leading to the company halting its development. Users discussed their disappointment and skepticism about hair loss treatments, with some mentioning other treatments like Minoxidil, Finasteride, and RU58841.

      community Why is no one pointing out dandruff as the number 1 evidence/symptom of MPB?

      in Chat  55 upvotes 1 year ago
      The post discusses the theory that persistent dandruff in areas prone to hair loss could be a sign of hair follicles dying due to DHT, indicating balding. The responses vary, with some users noting improvements in dandruff and hair loss with treatments like Dutasteride, while others experienced hair loss without dandruff.