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      community One year of dudasteride and minoxidil daily

      in Progress Pictures 1 year ago
      This conversation details the impressive one year progress of a user's hair loss treatment, which included taking daily doses of dutasteride and minoxidil. Other users shared their own experiences with similar treatments, such as not having any shedding when starting, or having an oily scalp that improved significantly.

      community HLT Megathread on HMI-115 (key takeaways in comments)

      in Research/Science  39 upvotes 1 year ago
      HMI-115, a newly discovered hair loss treatment that could potentially be effective for those with diffuse thinning and telogen effluvium. It is based on prolactin receptor antagonist signaling and has already undergone Phase I trials in women, with potential commercialization by 2027.

      community My Research Compilation on Nutrafol

      in Research/Science  10 upvotes 1 year ago
      Nutrafol, a hair loss supplement, has limited and potentially biased research, with one study showing a 10% increase in hair count for women after 6 months but no significant results for men. The user concludes that cheaper, well-studied options like minoxidil may be more effective, especially for men, given the lack of evidence supporting Nutrafol.

      community Why only the top of the head?!

      in Chat 1 year ago
      Why the top of the head is affected by hair loss more than other areas, and treatments such as surgery, medications like minoxidil, finasteride, and RU58841 to treat it.

      community No side effects on pyrilutamide / KX-826 so far

      in Research/Science  208 upvotes 2 years ago
      User TopBack56 and friends tried pyrilutamide (KX-826) for hair loss without experiencing negative side effects. They observed fine vellus hairs but no thick hair growth yet, and plan to add GT20029 to their regime after safety trials.

      community The theory that explains everything. Please help me make this big!

      in Research/Science  2449 upvotes 3 years ago
      The post and conversation are about the role of the enzyme 3alpha-hydroxysteroid reductase in hair loss and the potential of compounds like procyanidin B2 and sulforaphane to boost its activity for hair regrowth. Further research is needed to develop effective treatments based on this theory.

      community Help with Routine for 50 year old Black Woman

      in Female 4 years ago
      A 50-year-old Black woman with alopecia areata and traction alopecia is seeking a science-based hair loss routine. Current treatments include spearmint tea for DHT levels and considering PRP.

      community BREEZULA COVID UPDATE: Filing for Special Protocol Assessment with FDA

      in Research/Science  62 upvotes 4 years ago
      The conversation discusses the progress of Clascoterone (Breezula) for hair loss treatment, noting that COVID-19 delayed female trials by three months but Phase III trials for males are proceeding with a Special Protocol Assessment filed with the FDA. Users express hope for Breezula as an alternative to existing treatments like finasteride and minoxidil, despite concerns about its potential high cost.

      community Redensyl (The Ordinary Serum)

      in Treatment  19 upvotes 4 years ago
      Redensyl, a hair loss treatment that has been claimed to be 80% more effective than minoxidil, but users have not experienced any results from using it.

      community My boy Saul Goodman was on Minoxidil tabs too

      in Satire  1858 upvotes 1 month ago
      Saul Goodman was humorously depicted using high doses of minoxidil, finasteride, and spironolactone for hair loss. The conversation jokes about the unrealistic dosages and their potential side effects.

      community Treating MPB while dealing with seborrheic dermatitis?

      in Treatment  8 upvotes 2 months ago
      The user is seeking advice on treating male pattern baldness (MPB) while dealing with seborrheic dermatitis, specifically asking about the use of finasteride (Fin) and minoxidil (Min). They are concerned about side effects and are looking for recommendations to improve overall hair thickness, especially on the crown.

      community (Serious) Updates and discussion, new treatments in development

      in Treatment  6 upvotes 3 months ago
      Finasteride, minoxidil, and derma rolling are currently the best treatments for hair loss. New treatments like TDM-105795, GT20029, PP405, HMI 115, Tsuji, Scube 3, RU, JW0061, Topilutamide, and verteporfin show promise but have uncertain timelines.

      community Rosemary out here changing lives for the better

      in Treatment  90 upvotes 3 months ago
      Rosemary oil is being used as an addition to minoxidil and finasteride for hair health, with mixed opinions on its effectiveness. Some users report positive results, while others see no benefit or experience adverse effects.

      community 2 Years Results - 0.5mg Fin Only.

      in Progress Pictures  442 upvotes 3 months ago
      A user shared their 2-year results using only 0.5mg finasteride for hair loss, noting improvement after 8-10 months and no major shedding or side effects. They are 34 years old and have avoided using Minoxidil.

      community What's the deal with Zinc and DHT?

      in Chat  47 upvotes 4 months ago
      The conversation discusses the conflicting information about Zinc's effect on DHT and its role in hair loss. It mentions that Zinc can act as a 5AR inhibitor at high doses but may increase DHT if taken to correct a deficiency, and highlights the importance of nutritional balance for hair health.

      community HMI 115 Phase 2 - Leaked pics from Discord

      in Research/Science  362 upvotes 4 months ago
      The conversation discusses HMI 115, a new hair loss treatment with promising results, showing a significant increase in hair density after two months. Some users are skeptical, while others are hopeful for its release and potential affordability.

      community So is GT20029 available on the grey market anywhere?

      in Treatment  15 upvotes 5 months ago
      The conversation discusses the availability of GT20029, a new topical hair loss treatment with fewer side effects than Minoxidil or finasteride. Users suggest using finasteride to preserve hair until GT20029 becomes available.

      community Expectations control for SCUBE3

      in Research/Science  20 upvotes 6 months ago
      SCUBE3, a protein linked to hair growth in moles, was discovered over 25 years ago and is being developed by Amplifica for potential hair loss treatment. Concerns exist about SCUBE3's association with cancer, as it is a protein that promotes cell growth, which could potentially trigger cancer development if used for hair growth therapy.

      community PYRILUTAMIDE PHASE 3 RESULTS : No statistical significance

      in Research/Science  124 upvotes 10 months ago
      The phase 3 trial results for Pyrilutamide showed no significant difference from the control treatment in increasing hair count, leading to the company halting its development. Users discussed their disappointment and skepticism about hair loss treatments, with some mentioning other treatments like Minoxidil, Finasteride, and RU58841.

      community Is DUT better or worse than FIN?

      in Finasteride/Dutasteride  62 upvotes 11 months ago
      The conversation discusses the effectiveness of Dutasteride (DUT) and Finasteride (FIN) for hair loss. Users share varied experiences, with some finding DUT more effective and others experiencing side effects or no change, highlighting that individual responses can vary.