Potential side effects of 5AR inhibitors like finasteride and dutasteride. Users debate risks, benefits, and personal experiences with these hair loss treatments.
A YouTuber named Kevin, also known as Rider_Of_Roach, who deleted his YouTube channel due to personal attacks and controversy surrounding his views on hair loss treatments. He advocated for FDA-approved treatments like finasteride and minoxidil but faced backlash from those who disagreed with him. The conversation also discusses his past trolling behavior and a lawsuit he filed against a website that published false information about him. Despite some disagreements, many viewers appreciated his research-based content and hope to see him return in the future.
The conversation discusses the theory that scalp fibrosis contributes to male pattern baldness (MPB) by increasing DHT concentration, and mentions treatments like Minoxidil. The user seeks opinions on the theory and the effectiveness of scalp massages.
User shared 5.5-month progress using 0.5mg finasteride, 5% minoxidil, 1.5mm microneedling weekly, and 20mg RU58841, with positive results and no side effects. Others discussed their experiences, dosage adjustments, and the importance of age in treatment efficacy.
Creatine may increase scalp DHT without affecting serum DHT, potentially speeding up male pattern baldness (MPB) for those genetically prone. Treatments mentioned include Minoxidil, finasteride, and RU58841.
Regrowing hairline without the use of Minoxidil or Finasteride, and instead using mechanical stimulation such as Derma Roller, Nizoral, Zinc Pyrithione, Scalp Massage, Scalp Exercise, Fish Oil and other topical solutions. It is cautioned that there are risks associated with not using medically-prescribed treatments, but it is suggested to consider mechanical stimulation in addition to those prescribed treatments.
A user shared their two-year progress using 2.5mg finasteride daily and minoxidil twice daily, recently adding topical dutasteride. Another user questioned the high finasteride dosage, noting no benefits over 1mg.
Balding seems to worsen with each generation, possibly due to stress, diet, and environmental factors. The user started treatments like Minoxidil and finasteride.
Topical Finasteride doesn't directly reduce 5ar enzyme on scalp and has the same mechanism as oral, needing to go through the liver. Users debate the accuracy of this information and discuss various studies and experiences.
Comparing the effectiveness of minoxidil 5% and adenosine 0.75% for treating male androgenetic alopecia, and measuring patient satisfaction rate; results showed that adenosine is comparable to minoxidil but provides quicker results, however availability of products with adenosine is much less than those with minoxidil.
User shared 9 months of progress using 1 mg finasteride and topical minoxidil, showing photos from different stages. Encouragement was given to continue the treatment.
The conversation discusses natural DHT blockers like rice bran oil, which may reduce 5α-reductase activity similarly to Minoxidil and Dutasteride. One user argues that finasteride is more reliable and effective than natural alternatives.
User shared 1-year progress on Fin 1 mg, switching to 0.4 mg Dut and oral 1.25 mg Min. Good results with Fin, biotin supplement, and biotin shampoo; trying Dut and oral Min for potential better results.
User Crazy-Signature930 shares progress on oral minoxidil for eyelashes and eyebrows. Others comment on the impressive results and ask about side effects and duration of use.
The efficacy of degrading the androgen receptor through dermal application in DP cells, a delivery system for topical drugs that involves dissolving microneedles, and rosemary oil as an alternative anti-androgen.
Users discuss aggressive promotion of Koshine 826, suspecting Kintor employees are behind it. Concerns are raised about its effectiveness, with some preferring alternatives like finasteride and minoxidil.
User tried oral finasteride, topical finasteride, topical dutasteride, and RU58841 but experienced side effects. They discuss upcoming treatments like clascoterone, pyrilutamide, gt20029, and KY19382 as potential options.
The user underwent a hair transplant with 3500 grafts and has been using Finasteride and Minoxidil for 5.5 months, seeing some growth. They plan to have a second transplant for the crown area and are seeking opinions on future results and density improvement.
A 32-year-old man has been using topical minoxidil for 11 years and oral finasteride for 1 year, along with a dermaroller, and is happy with his hair regrowth progress without experiencing side effects. Commenters are impressed and some are considering starting finasteride after seeing his results.
Dutasteride is likely the most effective treatment for male pattern baldness, followed by finasteride and minoxidil in various forms and dosages. Users discuss personal experiences, dosages, and potential side effects, with some considering combining treatments for better results.
The user is considering switching from finasteride to dutasteride for hair loss. They are unsure if GT20029 can regrow hair, particularly on the temples. Another user mentions that regrowth on finasteride can take up to 2 years.
Increased hair fall after starting minoxidil, dutasteride, and biotin is normal. Hair may grow faster, and shaving your head is fine while on these medications.
A user shared their hair regrowth progress after a year of derma stamping, daily minoxidil, and four months of oral finasteride, along with regular workouts. Others discussed the effectiveness of these treatments and additional methods like red light therapy and RU58841.
A user encouraged others experiencing hair loss to try shaving their heads, sharing their own positive experience despite briefly using finasteride and natural methods. Responses were mixed, with some supporting the decision and others suggesting treatments like minoxidil and finasteride, while many commented on the appearance changes.
A user shared their positive experience with hair regrowth after 3 months of using 6% Minoxidil and 0.3% Finasteride spray. They experienced temporary erectile dysfunction but it resolved, although morning erections are less frequent.
A 28-year-old shared his 2-year hair loss treatment progress using finasteride, minoxidil, dermarolling, and Revita shampoo. He saw significant improvement, especially with minoxidil and dermarolling, and stressed consistency.
The conclusion of the conversation is that the user has experienced significant hair regrowth using a combination of medications, including dutasteride, RU58841, and minoxidil. They have not experienced any noticeable side effects and are considering a hair transplant in the future.
The conversation is about using vitamin C and Magnesium L-Threonate for hairgrowth by reducing DHT binding to dermal papilla cells. The original post about vitamin C's pH levels and sebum control was possibly removed by a moderator.
Calecim (PTT-6) Advanced Hair System is a 6-week hair restoration product using stem cell-derived ingredients to stimulate hairgrowth. Users are skeptical, calling it overpriced and ineffective, suggesting alternatives like LLLT devices or PRP treatments.