User experiencing hair loss on dutasteride; others suggest shedding is normal and to track progress with pictures. Some mention using RU58841 for improvement.
The user shared their 4-year hair regrowth progress using finasteride, minoxidil, estradiol, and spironolactone. They noted significant regrowth by the second year and additional benefits from estradiol and spironolactone.
A 22-year-old man experienced significant hair loss after stopping minoxidil and finasteride, causing emotional distress. He resumed these treatments and is considering dutasteride and microneedling to manage his hair loss.
Stopping minoxidil causes significant hair loss, as continued use is necessary for maintaining gains. Combining minoxidil with finasteride may help maintain hair, but both treatments are typically lifelong commitments.
A user took finasteride for six months, then switched to dutasteride for a year, increasing the dosage over time, but hair shedding worsened. Replies suggest the issue is male pattern baldness and DHT-related.
A 25-year-old with AGA experienced hair thinning and dandruff, stabilized with topical finasteride and minoxidil but saw minimal regrowth. They seek advice on styling and consider oral minoxidil and microneedling for denser hair.
Pyrilutamide, a potentially effective hair loss treatment; other topical treatments like RU58841 and CB-03-01 that may have fewer side effects than Pyrilutamide; and the Phase 3 clinical trials of Pyrilutamide, which is likely to be approved by the FDA soon.
There is no natural way to stop hair loss; pharmaceuticals like minoxidil, finasteride, and RU58841 are the only effective treatments. Some users report success with minoxidil and microneedling, while others discuss the side effects of finasteride.
A user's progress using minoxidil and dutasteride mesotherapy to treat hair loss, with advice from other users on whether or not to continue the treatment. Suggestions included trying oral treatments such as finasteride and RU58841, and considering a hair transplant for more significant results.
User "manlycoffee" shares 25-month progress using Dutasteride, RU58841, Minoxidil, Microneedling, Nizoral, T/GEL, and fixing vitamin D levels for hair loss. Users discuss sources, experiences, and side effects of treatments.
A gel of keratin microspheres promotes hairfolliclegrowth, showing similar effectiveness to minoxidil in mice. The treatment activates hairgrowth pathways and reduces inflammation, with potential applications in drug delivery for hair-related disorders.
Hairgrowth can be induced without stopping DHT, as seen with Minoxidil. HMI115 may work by promoting folliclegrowth, not targeting the root cause of hair loss (DHT).
TDM-105795 showed promising hairgrowth results, with higher efficacy than placebo and minimal side effects. It activates dormant hairfollicle stem cells and may maintain gains without immediate loss, unlike minoxidil.
He Shou Wu (Fo Ti) extract was found to prolong the hairgrowth phase, inhibit 5-alpha-reductase (like finasteride), reduce androgen receptors, and increase growth factors, potentially outperforming minoxidil in recovering hairfollicle size after DHT exposure. Two compounds, emodin and TSG, are identified as responsible for these effects and warrant further investigation.
New potential hair loss treatment uses molecules from hairy moles to stimulate folliclegrowth. Topical solution requires less frequent application, like Botox injections a few times per year.
The conversation discusses why DHT (dihydrotestosterone) negatively affects scalp hair but promotes growth elsewhere on the body. Various opinions include genetic predispositions, differences in hairfollicle reactions to DHT, and the potential role of Omega-3 in reducing inflammation and promoting hair health.
Hair regrowth in transfems is more effective due to hormonal changes, specifically estrogen, which keeps hair in growth phase longer. Treatments mentioned include anti-androgens, sex hormones, and DHT blockers like finasteride.
Finasteride prevents further hair loss by blocking DHT, while minoxidil stimulates hairgrowth by prolonging the active phase of hairfollicles. Stopping minoxidil can lead to loss of regrown hair because finasteride does not address the same growth mechanism.
Peptides like TB500, KPV, GHK-CU, and BPC-157 are overhyped for hairgrowth with limited proven effectiveness in humans. Combining peptides with delivery methods like iontophoresis and sonophoresis shows promise, but many claims remain unproven.
Androgenetic alopecia is caused by DHT affecting hairgrowth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hairgrowth.
Microneedling is effective for hairgrowth, especially when combined with finasteride and minoxidil, but concerns exist about potential long-term skin damage. Users report increased collagen and elastin deposition, but the long-term effects on the scalp remain uncertain.
The conversation discusses the effectiveness of minoxidil for hair loss after one month of use, with a user questioning if complete hair regrowth is possible and another suggesting the perceived improvement may be due to lighting differences rather than actual hairgrowth.
This user has had success with Minoxidil foam, achieving significant hairgrowth in three months without using finasteride or derma rolling. They are considering incorporating a DHT reducing strategy such as finasteride in the future.
The conversation discusses hair loss linked to BDNF-increasing nootropics like Semax and Lions Mane. Suggested topical treatments include capsaicin, beta-glucan, and ginseng to counteract TGF-B activation.
A 38-year-old female is experiencing hair loss despite having almost undetectable DHT levels after using dutasteride. Suggestions include checking for PCOS, thyroid issues, adjusting diet, considering the impact of birth control, and trying treatments like tretinoin, redensyl, retinol, and minoxidil with derma stamping.
The "Big 3 Stack" for hair loss treatment, which includes Minoxidil for hair density improvement, Ketoconazole shampoo for enhancing hair volume and thickness, and Finasteride for blocking hair loss causing hormones. Microneedling can boost Minoxidil's effects.
GT20029, a new hair loss treatment, shows promising results but only a slight improvement over placebo. People are cautiously optimistic, discussing its potential and combining it with existing treatments like Minoxidil and Finasteride.