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This post and conversation are about using scalp slapping to increase blood flow for hair growth. One user suggests using minoxidil instead.

SCUBE3, a protein linked to hair growth in moles, was discovered over 25 years ago and is being developed by Amplifica for potential hair loss treatment. Concerns exist about SCUBE3's association with cancer, as it is a protein that promotes cell growth, which could potentially trigger cancer development if used for hair growth therapy.

Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.

User TopBack56 and friends tried pyrilutamide (KX-826) for hair loss without experiencing negative side effects. They observed fine vellus hairs but no thick hair growth yet, and plan to add GT20029 to their regime after safety trials.

The post discusses the difference in effects of Minoxidil (Min) on scalp and facial hair. The user questions why Min-induced hair growth on the scalp is temporary, while facial hair growth seems permanent, even after stopping Min. They propose theories, including different Min mechanisms on body and facial hair, the role of DHT, and the possibility of not achieving fully terminal hair. The responses include personal experiences and theories about Min's effects on hair growth.

The user "macroburstmedia" is asking if adding topical minoxidil to their current treatment of oral minoxidil and finasteride can improve hair growth. Some users have shared their experiences with using both oral and topical minoxidil, while others suggest increasing the oral minoxidil dose instead.

The conversation discusses microneedling techniques and the use of Minoxidil, copper peptides, EGF, FGF, ceramides, and hydration serums to enhance hair growth. It explores optimizing scalp conditions and the potential benefits of various compounds in conjunction with microneedling.

The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.

Minoxidil, often combined with microneedling, has helped some users improve hair growth at the temples and hairline. Finasteride is also mentioned as a treatment, with mixed results on its effectiveness.

42-year-old used finasteride, minoxidil, dermapen, and nizoral for 12 months, achieving significant hair growth. Consistency and patience are important for success.

The conversation discusses expectations for the release of Breezula, a new hair loss treatment, and compares it to existing treatments like finasteride. Some believe Breezula could be a game-changer due to fewer side effects, while others await more permanent solutions like hair follicle cloning.

Fin and minoxidil, in combination with dermarolling, as an effective path for hair growth. The post also provides advice about needle depth and frequency, as well as other treatments (foam and oral) which may be beneficial.

A hair transplant surgery involving 3000 grafts and the daily use of oral finasteride and topical minoxidil for four months since that procedure.

Adding tretinoin to a minoxidil routine can cause initial hair shedding, which may be normal as it potentially increases minoxidil's efficacy. Users suggest being cautious with tretinoin application, especially around microneedling, to avoid increased systemic absorption.

The conversation discusses hair loss linked to BDNF-increasing nootropics like Semax and Lions Mane. Suggested topical treatments include capsaicin, beta-glucan, and ginseng to counteract TGF-B activation.

Hair loss treatments like minoxidil, finasteride, TDM-105795, and PP405. MIT is hosting a hackathon to find innovative hair loss solutions.

Finasteride and minoxidil can revive hair dormant for up to 7 years, with microneedling enhancing regrowth. Users report significant hair regrowth even after long periods of baldness.

Hair follicles don't truly die but become severely miniaturized. Treatments like finasteride, dutasteride, and minoxidil can help restore hair by providing nutrients and reducing harmful effects on hair roots.

The user shared a two-year hair regrowth update after using 1mg Finasteride daily and Minoxidil liquid once daily, with significant improvement and no side effects. Some users suggested adding derma rolling to the regimen, while others discussed the effectiveness of Finasteride alone before considering Minoxidil.

The conversation is about alternative measures for hair regrowth for those who did not respond to finasteride or dutasteride, including the use of minoxidil and addressing vitamin deficiencies through blood tests.

Factors that can cause hair loss other than DHT, such as inflammation and diet, and potential treatments like scalp massages, minoxidil, citrulline, stretches, meditation, iron sulfate/Vitamin C, Vitamin D, protein and Dutasteride.

A 27-year-old man saw significant hair regrowth after starting a regimen in January that included topical minoxidil with finasteride, vitamins D and B12, fish oil, zinc with magnesium, quitting smoking, and intermittent fasting. People commented on the effectiveness of minoxidil in Southern populations and asked about the details and timeline of his treatment.

Finasteride, Minoxidil, Bioneer CosmeRNA, Technoderma, Kintor, Hope, Breezula, and Follicum treatments showed increases in hair count, with Technoderma showing the highest increase at 24.3 hairs/cm². Amplifica has not yet published results.

Testosterone within the normal range does not significantly contribute to male pattern baldness (MPB); DHT is the main factor that can be controlled. Genetics play a crucial role in hair loss, and treatments like finasteride and dutasteride, which block DHT, can help despite potentially raising testosterone levels.

A user who has been shaving his head for 15 years looking for potential treatments to regrow hair; the replies range from advice to try out medications such as finasteride and minoxidil, to suggestions of changing up his look with facial hair or hobbies.

A human trial of verteporfin, a potential treatment for hair loss, with some users noting potential improvements in scarring and overall healing compared to control areas.

Hair loss treatments like finasteride, minoxidil, ketoconazole, PRP, and microneedling helped maintain hair for 20 years. Research and try evidence-based treatments for best results.

Dutasteride at 2.5mg is considered a potential hair loss cure due to its DHT-blocking ability, but there are concerns about side effects and individual responses. Minoxidil, finasteride, and RU58841 are also discussed, with mixed opinions on their effectiveness and safety.

A dental technician claims malocclusion causes pattern hair loss due to poor scalp circulation. Users debate this, noting treatments like finasteride, minoxidil, and microneedling focus on DHT and blood flow.

User experienced significant hair loss after adding dutasteride to their finasteride and minoxidil regimen. They plan to revert to finasteride only due to lack of improvement.