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      community PP405 - hair stem cell stimulation

      in Research/Science  51 upvotes 8 months ago
      PP405, a topical LDH inhibitor, has shown to stimulate hair follicle stem cell proliferation in humans with moderate hair loss. They are advancing to more detailed trials this year.

      community ~3 year update on my singular DHT immune hair for you guys

      in Update  20 upvotes 1 year ago
      The post is an update on the user's hair loss journey. They have a strong hair follicle that has remained unaffected by hair loss for almost 3 years. The user is starting finasteride and using ketoconazole, alfatradiol, and oral castor oil for hair maintenance.

      community Polydopamine Synergizes with Quercetin Nanosystem to Reshape the Perifollicular Microenvironment for Accelerating Hair Regrowth in Androgenetic Alopecia.

      in Research/Science  13 upvotes 6 months ago
      A quercetin-encapsulated and polydopamine-integrated nanosystem (PDA@QLipo) shows promise for treating androgenetic alopecia by reshaping the perifollicular microenvironment, outperforming minoxidil in hair regeneration. The nanosystem promotes cell proliferation, hair follicle renewal, and recovery by scavenging reactive oxygen species and enhancing neovascularity.

      community HairClone: Good info from their site

      in Technology  10 upvotes 2 years ago
      HairClone aims to rejuvenate miniaturizing hair follicles through follicle banking and cell expansion, with treatments potentially available in the UK by 2022. The process involves extracting, storing, and cloning hair follicles, but full regenerative treatments will take many years to develop.

      community Keratin microspheres - breakthrough

      in Research/Science  13 upvotes 8 months ago
      A gel of keratin microspheres promotes hair follicle growth, showing similar effectiveness to minoxidil in mice. The treatment activates hair growth pathways and reduces inflammation, with potential applications in drug delivery for hair-related disorders.

      community TDM-105795 phase 2 results are in!

      in Research/Science  28 upvotes 9 months ago
      TDM-105795 showed promising hair growth results, with higher efficacy than placebo and minimal side effects. It activates dormant hair follicle stem cells and may maintain gains without immediate loss, unlike minoxidil.

      community The 'DHT itch' is real - notes from a casual bodybuilder

      in Chat  115 upvotes 2 months ago
      The "DHT itch" is real and likely due to inflammation at the hair follicle, exacerbated by increased testosterone or androgens. Treatments mentioned include dutasteride, minoxidil, finasteride, and various topical solutions.

      community Pyrilutamide phase III clinical trial results released

      in Research/Science  31 upvotes 11 months ago
      Pyrilutamide did not show effectiveness in regrowing hair compared to a placebo, but it may still help maintain existing hair by preventing DHT from causing follicle miniaturization. Some users believe it could be beneficial when used with other treatments like minoxidil, finasteride, and dutasteride.

      community Best Microneedle Lengths To Stimulate Stem Cells

      in Microneedling  18 upvotes 1 year ago
      Microneedling with needle lengths of 1.5mm to 2.5mm to stimulate hair follicle stem cells for potential hair growth. Using needles longer than 2.5mm is not recommended due to risk of puncturing veins in the scalp. A dermastamp is suggested over a roller.

      community Pre and Post Dermarolling Routine?

      in Microneedling  18 upvotes 4 years ago
      The conversation is about a hair loss treatment routine involving dermarolling, finasteride, minoxidil, and natural oils. Suggestions include using shorter needles for better absorption of treatments and longer needles less frequently for hair follicle regeneration.

      community Cure/better treatment options in the future

      in Chat  11 upvotes 3 months ago
      The conversation is about future hair loss treatments. Current treatments mentioned include finasteride, minoxidil, and RU58841, with potential future treatments like GT20029, TDM-105795, JW0061, and follicle cloning.

      community Surprisingly thorough study on He-Shou-Wu/Fo Ti

      in Research/Science  14 upvotes 1 year ago
      He Shou Wu (Fo Ti) extract was found to prolong the hair growth phase, inhibit 5-alpha-reductase (like finasteride), reduce androgen receptors, and increase growth factors, potentially outperforming minoxidil in recovering hair follicle size after DHT exposure. Two compounds, emodin and TSG, are identified as responsible for these effects and warrant further investigation.

      community 24F, minodixil, saw palmetto, biotin, rosemary oil, advice?

      in Question  6 upvotes 5 years ago
      A 24-year-old woman with thinning hair is using Minoxidil, saw palmetto, biotin, rosemary oil, and ketoconazole. She seeks advice on whether to try finasteride or dutasteride, the effects of Minoxidil shedding, and the significance of her hair follicle condition.

      community Injured temple with derma rolling

      in Microneedling  2 upvotes 2 months ago
      OP injured their temple using derma rolling and tretinoin, causing peeling and potential hair follicle damage. Users suggest the injury might be permanent, possibly resulting in scar tissue where hair won't grow.

      community 3 Months Fin/Min/Microneedling

      in Progress Pictures  250 upvotes 7 months ago
      The user shared a 3-month progress update on hair loss treatment using finasteride (1 mg), minoxidil (5% once or twice daily), and microneedling (1.5mm every 2 weeks) with no side effects. Commenters are impressed, discussing hair follicle revival and the user's method, noting the hair appears darker.

      community Is this broscience? From More Plates, More Dates

      in Research/Science  22 upvotes 8 months ago
      The conversation discusses whether finasteride's reduction of DHT and increase in scalp testosterone contribute to hair follicle miniaturization. Some participants argue testosterone does not cause miniaturization, while others suggest that even with reduced DHT, other androgens like testosterone may still contribute to hair loss.

      community 3 months fin/min progress (age 31)

      in Progress Pictures  168 upvotes 2 months ago
      A user shared their 3-month progress using 1mg oral finasteride daily and 5% topical minoxidil twice daily, along with Pura D’Or anti-thinning shampoo and a scalp massager. They noticed initial worsening but later saw hair follicle recovery.

      community When do you think Breezula will be released to the public?

      in Chat  34 upvotes 3 years ago
      The conversation discusses expectations for the release of Breezula, a new hair loss treatment, and compares it to existing treatments like finasteride. Some believe Breezula could be a game-changer due to fewer side effects, while others await more permanent solutions like hair follicle cloning.

      community Hair Oils can be DANGEROUS and this is a case study. He lost all his hair.

      in Treatment  7 upvotes 1 month ago
      Hair oils can cause severe allergic reactions, as seen in Jermel Brown's case, leading to significant health issues and legal action for damages. Users discussed concerns about various hair oils, including Mielle and Kiehl's, with some experiencing hair loss and others using treatments like Minoxidil and Finasteride to address damage.