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      community Comprehensive Microneedling Guide

      in Microneedling  295 upvotes 2 years ago
      Microneedling for hair restoration involves daily use of a 0.3 mm device and weekly use of a 0.5 mm device. Combining microneedling with Minoxidil can enhance hair growth.

      community What's your option on complementary treatment

      in Product  3 upvotes 5 months ago
      The conversation discusses complementary treatments for hair loss while using finasteride and minoxidil, including scalp massagers, scrubs, coconut oil, and vitamin supplements. The user seeks opinions on these additional treatments.

      community Keratin microspheres - breakthrough

      in Research/Science  13 upvotes 8 months ago
      A gel of keratin microspheres promotes hair follicle growth, showing similar effectiveness to minoxidil in mice. The treatment activates hair growth pathways and reduces inflammation, with potential applications in drug delivery for hair-related disorders.

      community Pyrilutamide update: three months

      in Update  33 upvotes 1 year ago
      A user's 3-month experience with pyrilutamide to reduce hair shedding, and how it may not be strong enough to stop the thinning of their hairline. Other users mentioned the effectiveness of minoxidil and finasteride for treating hair loss.

      community Stopped minoxidil for a year after a year of using it. Starting again.

      in Minoxidil  158 upvotes 2 years ago
      ? This post by PastelDeUva discusses their experience with Minoxidil and Finasteride for hair loss treatments, which they stopped using for a year before resuming due to family's negative opinion. After restarting, they posted photos of the progression/regression of their hairline and are now planning on adding finasteride and dermarolling in order to get good results.

      community Verteporfin and Microneedling

      in Treatments 5 months ago
      Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.

      community Fevipiprant 2019!

       17 upvotes 8 years ago
      The conversation discusses Fevipiprant, an asthma drug that may block CRTH2 and potentially stop male pattern baldness (MPB) without inhibiting DHT. It also mentions the use of finasteride and dutasteride for hair loss.
      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 3 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Hair theory Scar tissue and Verteporfin

      in Chat  25 upvotes 5 months ago
      A user suggests that deeper microneedling with Verteporfin injections might help regrow hair in areas with scar tissue, alongside a DHT blocker. Another user explains that hair loss might be due to reduced Wnt/β-Catenin signaling and suggests that treatments like Minoxidil, Finasteride, and microneedling could potentially reverse it.

      community Natural Remedies: Polyphenols and Hair Loss

       19 upvotes 5 years ago
      Natural remedies to treat hair loss, such as polyphenols, apple peel extract, grape seed extract, green tea extract, peppermint oil, pumpkin seed oil, apigenin, Ginkgo biloba, red clover extract, olive leaf extract, Ecklonia Cava and Grateloupia elliptica. In addition, terpenes, carotenoids, and tocopherols were discussed as potential treatments.

      community Extreme hair and beard growth from Stemoxydine. Big 3 + 1?

      in Product  23 upvotes 3 years ago
      Using a combination of Stemoxydine, minoxidil, dutasteride, and keto shampoo to achieve extreme hair and beard growth. The user has experienced positive results with terminal hairs at the hairline and an increase in density to their stubble after several weeks of use.

      community This serum outperformed Minoxidil in a recent study. Please debunk

       23 upvotes 5 years ago
      A topical solution called "Multi-Peptide Serum for Hair Density" by The Ordinary Company, which contains several ingredients that are used in alternatives to Minoxidil and was found to have better results than 5% Minoxidil in a study. People who have tried it shared their experiences with the serum as well.

      community Can we have a thread that summarizes all treatments options in addition to the big 3 which we have some evidence for, their mechanism of action and whether they can be combined with the big 3(other than dermarolling)?

      in Treatment  55 upvotes 6 years ago
      The conversation discusses hair loss treatments beyond the commonly known three, focusing on separating effective treatments from myths. Dutasteride and low-dose oral Minoxidil are mentioned as having clinical evidence for increasing hair counts, but with potential side effects.

      community HLT Megathread on HMI-115 (key takeaways in comments)

      in Research/Science  40 upvotes 1 year ago
      HMI-115, a newly discovered hair loss treatment that could potentially be effective for those with diffuse thinning and telogen effluvium. It is based on prolactin receptor antagonist signaling and has already undergone Phase I trials in women, with potential commercialization by 2027.

      community Update: 16 months deep - big 3

      in Progress Pictures  407 upvotes 1 year ago
      The user has seen positive results after 16 months of using topical Finasteride/Minoxidil, microneedling weekly, and Tretinoin for hair loss. There are no reported side effects, and the user advises that the effectiveness of microneedling depends on the pressure applied.

      community Novel effect of sildenafil (cialis) on hair growth

      in Research/Science  21 upvotes 2 years ago
      Sildenafil (Viagra) shows potential for hair growth by enhancing dermal papilla cell proliferation and stimulating perifollicular vessel formation. Users discuss the possibility of using Cialis (tadalafil) similarly, noting its benefits and side effects.

      community KX-826: Long-Term Safety Results are out!

      in Research/Science  158 upvotes 1 month ago
      KX-826 initially improves hair growth but declines after 24 weeks, with mild itching as a side effect. Combining it with minoxidil and finasteride may improve results, but long-term effectiveness is uncertain.