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    GlossaryIntestinal Stem Cells (gut stem cells)

    specialized cells in the gut that regenerate intestinal lining

    Intestinal Stem Cells (ISCs) are specialized cells located in the lining of the intestines that have the ability to self-renew and differentiate into various types of cells that make up the intestinal epithelium. These cells are crucial for maintaining the integrity and function of the gut by continuously replenishing the intestinal lining, which is constantly being worn down by digestive processes.

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      community Fun thought experiment about halting hair loss permamently

      in Research/Science  58 upvotes 4 months ago
      A user proposed genetically engineering scalp stem cells to stop androgen receptors from causing hair loss. Others discussed the feasibility, existing research, and potential issues with this approach, including targeting the correct cells and unintended effects.

      community Dr. Bloxham's Verteporfin Trial

      in Research/Science  29 upvotes 1 year ago
      Dr. Bloxham's trial is testing verteporfin on hair transplant patients to see if it can improve hair regrowth in treated areas. People are discussing the potential for follicle regeneration, expected results timeline, and concerns about side effects like cancer.

      community Massive hair gains! Hope! May this post be a light to you in dark phases when all other lights go out

      in Progress Pictures  192 upvotes 4 months ago
      A 27-year-old man saw significant hair regrowth after starting a regimen in January that included topical minoxidil with finasteride, vitamins D and B12, fish oil, zinc with magnesium, quitting smoking, and intermittent fasting. People commented on the effectiveness of minoxidil in Southern populations and asked about the details and timeline of his treatment.

      community C’est terrible - at my wits end

      in Female  449 upvotes 10 months ago
      A 29-year-old woman is experiencing gradual hair thinning since age 15, suspects Androgenic Alopecia, and has tried 5% minoxidil with little success. She has purchased various hair loss treatments including minoxidil, dutasteride, finasteride, and spironolactone, but is cautious about starting them due to potential interactions with her ADHD medication.

      community The Worst Hair Loss Condition You (MAY) have: LPP

      in Research/Science  43 upvotes 4 weeks ago
      Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.

      community The theory that explains everything. Please help me make this big!

      in Research/Science  2452 upvotes 3 years ago
      The post and conversation are about the role of the enzyme 3alpha-hydroxysteroid reductase in hair loss and the potential of compounds like procyanidin B2 and sulforaphane to boost its activity for hair regrowth. Further research is needed to develop effective treatments based on this theory.

      community 1.5 years fin plus almost 3 years min, I think I’ve definitely made progress but I’m still not where I want to be, advice?

      in Progress Pictures  130 upvotes 8 months ago
      The user has been using finasteride for 1.5 years and minoxidil for almost 3 years for hair loss, and has seen some maintenance of hair but not significant regrowth. Suggestions from others include switching to dutasteride, trying oral minoxidil, and considering microneedling or hair fibers for better appearance.

      community Bald groom beaten over fake hair.

      in Satire  881 upvotes 1 year ago
      A bald groom was beaten by the family of the bride for wearing a wig. The conversation discusses the cultural stigma around baldness in India and the consequences of deception in arranged marriages.

      community Gyno & testoterone level

      in Finasteride  282 upvotes 3 months ago
      Switching from finasteride to dutasteride and back to finasteride led to gynecomastia and fatigue, likely due to hormonal imbalances. Suggested treatments include Tamoxifen, Raloxifene, or low-dose Anastrozole, with a recommendation to test testosterone and estradiol levels.

      community Do any of you guys feel like your 20s have been wasted?

      in Chat  184 upvotes 4 months ago
      A user expressed frustration about hair loss and its impact on their 20s, mentioning financial struggles and mental health concerns. Responses included advice on positive thinking, self-improvement, and seeking treatment options like Minoxidil and finasteride.

      community The link between hair loss and gut health

      in Research/Science  59 upvotes 4 years ago
      The conversation discusses the potential link between gut health and hair loss, with personal experiences of hair thinning and stomach issues shared. Some individuals found no success with common hair loss treatments like Minoxidil and Finasteride and are exploring the impact of gut health on hair growth.

      community Pattern hair loss could be due to gut bacteria

       48 upvotes 4 years ago
      Feeding bacteria-free mice with Lactobacillus murinus worsened hair loss, but a regular diet with biotin stopped it. The conversation suggests gut bacteria and diet may influence hair loss, with some skepticism and discussion about other factors like DHT and genetics.

      community Anything you use without scientific backing, just trusting your gut?

      in Research/Science  14 upvotes 1 year ago
      The conversation discusses using peppermint oil for hair loss, with one user applying it undiluted to the scalp and another combining it with finasteride and microneedling. Some believe in its effectiveness despite limited scientific evidence, and also mention rosemary oil as potentially beneficial.

      community Malabsorption: Nutrient Testing and Supplementation

      in Treatment  2 upvotes 1 month ago
      The user is experiencing severe hair loss due to gut malabsorption and is seeking advice on nutrient testing and supplementation. They have low Vitamin D and Ferritin levels and are asking for recommendations on additional nutrients and blood tests to consider.

      community I was a non-responder to Minoxidil before my esophagus surgery

      in Research/Science  38 upvotes 8 months ago
      The user experienced improved hair density after switching from 5mg to 2.5mg oral Minoxidil post-esophagus surgery, suggesting a possible link between gut health and hair growth. They theorize that long-term medication may have blocked nutrient intake, affecting hair regrowth.

      community grass fed collagen worked for my alopecia

      in Female  13 upvotes 4 years ago
      A woman found that taking grass-fed collagen powder helped with her alopecia, leading to hair regrowth and reduced hair loss. She initially took it for gut issues, not hair, and also noticed improvements in arthritis and reduced bruising.

      community The ultimate regiment to reverse hairloss

      in Treatment  6 upvotes 1 year ago
      The conclusion of the conversation is that the user "Shakalakaplaka" shares their comprehensive hair loss regimen, which includes various treatments targeting different pathways such as DHT, inflammation, fibrosis, immune system, testosterone, gut problems, and scalp health. The effectiveness of the regimen is not confirmed, and some users express skepticism or request before and after pictures for credibility.

      community How uninformed the general public is about hair loss

      in Chat  313 upvotes 8 months ago
      The conversation highlights the general public's lack of knowledge about hair loss, with various ineffective remedies suggested, such as not wearing hats or using hair fibers. The only effective treatments mentioned for male pattern baldness are medications like minoxidil and finasteride, and hair transplants.

      community 1 Year Fin then 6 Months Dut - No Success

      in Finasteride/Dutasteride  4 upvotes 2 months ago
      The user saw no improvement in hair loss after using Finasteride for a year and Dutasteride for six months. They also experienced scalp inflammation and tried various treatments like Ketoconazole and Salicylic Acid without success.

      community Getting dutasteride in germany

      in Finasteride/Dutasteride  18 upvotes 2 months ago
      You can get dutasteride in Germany through the Teleclinic app, which sends a prescription to a nearby pharmacy. It costs around 18-19 euros for the prescription and 47 euros for 90 pills of Avodart 0.5.

      community Experience with Strut topicals?

      in Product  3 upvotes 5 months ago
      A user has been using a topical hair loss treatment with finasteride, minoxidil, and tretinoin for 4 years without satisfactory results and is considering switching to a different product due to concerns about effectiveness and company reliability. They are seeking others' experiences with Strut and alternative products before making a change.

      community [SAD UPDATE] 11 Months Topical Finasteride on TrichoSol - Hair got worse - Need Opinions

      in Progress Pictures  9 upvotes 6 months ago
      A user expressed disappointment that their hair loss worsened after 11 months using topical finasteride with TrichoSol, despite no side effects and initial signs of improvement. They asked for advice and opinions on their treatment and alternatives, with suggestions including switching to oral finasteride or dutasteride, starting minoxidil, and addressing their seborrheic dermatitis with different shampoos or medical advice.

      community Diffuse thinning fucking sucks

      in Update  430 upvotes 7 months ago
      The conversation discusses various treatments for hair loss, including finasteride, minoxidil, dutasteride, microneedling, and checking for nutrient deficiencies. Some users suggest adding hydrocortisone butyrate, low-dose progesterone, or tretinoin to treatment regimens, while others recommend cosmetic solutions like Toppik hair fibers or shaving the head.
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