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GlossaryGlycogen Synthase Kinase 3 (GSK-3)

enzyme involved in regulating cell functions and signaling pathways

Glycogen Synthase Kinase 3 (GSK-3) is an enzyme that plays a crucial role in various cellular processes, including the regulation of glycogen synthesis, cell division, and cell survival. It is involved in multiple signaling pathways and can influence conditions like diabetes, Alzheimer's disease, and even hair growth by affecting cellular functions and gene expression.

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community (26M) My 3 months progress on hair loss treatment. Extremely happy with the results. I have included so many details about my stack, my experience during the treatment, progress pictures, and everything I did during this time period.

in Progress Pictures 27 upvotes 1 year ago

A user's 3-month progress report on their treatment of hair loss using a stack of finasteride, dutasteride, and minoxidil, with additional supplements, diet and workout routine, and before-and-after photos.

community Dutasteride takes 1-3 months to work in the scalp. Not weeks. Be careful.

in Finasteride/Dutasteride 41 upvotes 1 month ago

Dutasteride takes 1-3 months to affect scalp DHT levels, not just a week. The prostate absorbs Dutasteride faster than the scalp due to different vascular networks and enzyme densities.

community Why is dutasteride approved for hair loss in Japan and South Korea but not for USA?

in Research/Science 34 upvotes 2 years ago

The reasoning for GSK's approval of dutasteride for hair loss in Japan and South Korea but not the US, with alternatives such as finasteride, minoxidil and RU58841 mentioned.

community Rate my dutasteride stock on 10

in Finasteride/Dutasteride 115 upvotes 1 year ago

Using Dutasteride as a hair loss treatment and its potential benefits, including availability in certain countries without a prescription and lower side effects than Minoxidil or RU58841.

community The truth about Dutasteride (w/ sources)

in Finasteride/Dutasteride 52 upvotes 1 year ago

The effectiveness of Dutasteride compared to Finasteride in treating hair loss, with evidence given such as studies and experiences, as well as discussion around whether one should switch from Finasteride to Dutasteride. There is also a discussion on post-Dutasteride syndrome.

community How do people afford finasteride/dutasteride?

in Treatment 27 upvotes 3 months ago

People discuss the high cost of brand name finasteride and dutasteride, suggesting generics as cheaper alternatives. They share prices from various regions, highlighting significant cost differences.

community At what point do you just drop all meds when its obvious that they don't work?

in Finasteride/Dutasteride 14 upvotes 6 months ago

The user has been on finasteride for over four years without noticeable results and recently added dutasteride and RU58841, but continues to experience hair loss. They are considering stopping all medications due to lack of effectiveness and side effects like extremely dry eyes from dutasteride.

community Transient and Permanent Effects of Finasteride Use

in Research/Science 154 upvotes 3 years ago

Potential side effects of 5AR inhibitors like finasteride and dutasteride. Users debate risks, benefits, and personal experiences with these hair loss treatments.

community Just to show you the superiority of dutasteride over finasteride (it's huge)

in Research/Science 58 upvotes 3 months ago

Dutasteride is shown to be significantly more effective than finasteride for treating male androgenic alopecia. Users discuss the difficulty of obtaining dutasteride in some countries and share personal experiences with its effectiveness and side effects.

community An argument for why we should take topical Dutasteride seriously

in Research/Science 85 upvotes 3 years ago

Topical Dutasteride may halt hair loss and effectively treat androgenic alopecia. Combining low-dose oral Dutasteride with topical application could maximize regrowth and minimize side effects.

community Dutasteride mesotherapy could practically cure the world of balding.

in Treatment 49 upvotes 3 years ago

Dutasteride mesotherapy showed increased hair density and diameter without reducing serum DHT levels in a small study. However, the sample size was too small to make definitive claims about its efficacy.

community Father trying to save his 17 year old son from MPB

in Progress Pictures 160 upvotes 2 years ago

Father assists son with hair loss using Finasteride Propecia. Son's hair improves, considers adding Minoxidil or Dutasteride for better results.

community Does melatonin dissolve in isopropyl alcohol

in Technology 8 upvotes 1 year ago

The conversation discusses making a topical melatonin solution for hair loss treatment, questioning if isopropyl alcohol can dissolve melatonin. Melatonin is soluble in lipids and alcohol, but it's unstable and should be mixed fresh regularly; it may help hair growth by affecting certain cellular signaling pathways and has anti-androgenic effects.

community Topical Valproic acid/sodium valproate — has anyone tried this?

in Question 2 upvotes 4 years ago

The conversation is about using valproic acid, an anti-seizure medication, as a topical treatment to promote hair growth. The original poster is seeking personal experiences from those who have tried this method.