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      community Peptides that Stop Hair Loss? | In-depth Literature Review Video

       76 upvotes 2 years ago
      Peptides like TB500, KPV, GHK-CU, and BPC-157 are overhyped for hair growth with limited proven effectiveness in humans. Combining peptides with delivery methods like iontophoresis and sonophoresis shows promise, but many claims remain unproven.

      community Expectations control for SCUBE3

       20 upvotes 2 years ago
      SCUBE3, a protein linked to hair growth in moles, was discovered over 25 years ago and is being developed by Amplifica for potential hair loss treatment. Concerns exist about SCUBE3's association with cancer, as it is a protein that promotes cell growth, which could potentially trigger cancer development if used for hair growth therapy.

      community Average r/bald user complaining

       401 upvotes 9 months ago
      Hair loss treatments like Minoxidil, finasteride, and RU58841, focusing on their effectiveness and side effects. It also highlights the disparity in medical research funding between hair loss and conditions like endometriosis.

      community My Delusional Hope - This page becomes irrelevant in 2030s

       54 upvotes 10 months ago
      People are hopeful for a permanent hair loss solution by the 2030s, considering options like hair cloning and treatments like pp405. Synthetic hair transplants have been attempted but are not effective long-term.

      community Finasteride and “anti-aging” effects

      in Treatment  218 upvotes 1 year ago
      Finasteride may help users look younger by suppressing DHT, affecting skin and hair. Users also emphasize skincare, sunscreen, and lifestyle for maintaining a youthful appearance.

      community Comprehensive Microneedling Guide

       292 upvotes 4 years ago
      Microneedling for hair restoration involves daily use of a 0.3 mm device and weekly use of a 0.5 mm device. Combining microneedling with Minoxidil can enhance hair growth.

      community We should actually be hopeful for these recent new developments

       112 upvotes 1 year ago
      AI advancements, like AlphaFold, are speeding up drug discovery for hair loss, promising more effective treatments. Current options like minoxidil and finasteride have limitations, but new developments could improve solutions in 5-10 years.

      community Amplifica: Hope or Cope? A Review of Their Pipeline

       9 upvotes 1 month ago
      Amplifica's AMP-303 showed a modest increase in hair growth, but results were inconsistent and potentially misleading. Hyaluronic acid and osteopontin are being explored for hair growth, with varying effects on different hair types and conditions.

      community Wtf have we been doing for the last 30 years

      in Treatment  548 upvotes 1 year ago
      Hair loss treatments like finasteride, minoxidil, and dutasteride work but have side effects. A permanent cure is still not available due to the complexity of hair loss and limited investment.

      community We already know how to permanently fix hair loss. The science is done. The only thing missing is the funding to run one experiment.

      in Technology  613 upvotes 4 months ago
      A permanent hair loss solution could involve reprogramming hair follicles to resist DHT using mRNA and siRNA. However, high costs, safety concerns, and the pharmaceutical industry's preference for ongoing treatments over one-time cures are major obstacles, with finasteride and minoxidil remaining standard treatments.

      community Being Safe on Oral Minoxidil: tl;dr on the literature.

       51 upvotes 1 year ago
      Oral minoxidil is effective for hair loss but can cause cardiovascular side effects, such as pericardial effusion, especially in those with genetic predispositions. Starting with low doses and monitoring cardiovascular health are advised to reduce risks.

      community Dermarolling is a bit sad innit?

      in Microneedling  232 upvotes 4 years ago
      Hair loss treatments discussed include dermarolling, minoxidil, finasteride, and RU58841. Some users find dermarolling sad, while others mention the complexity of biological systems and limited research funding for hair loss.

      community My DHT levels have increased after taking 0.25mg Fin for 47 days!

       186 upvotes 1 year ago
      A user experienced increased hair shedding and unchanged DHT levels after taking 0.25mg of finasteride for 47 days, leading them to increase the dose to 0.5mg. Others discussed varying experiences with finasteride, minoxidil, and the importance of measuring scalp DHT.

      community Dht kills hair, but no one says why?

      in Finasteride/Dutasteride  40 upvotes 1 year ago
      DHT affects hair follicles, contributing to hair loss, but the exact mechanism is unclear. Treatments like finasteride and minoxidil are used to manage hair loss, though they may have side effects and varying effectiveness.

      community Don’t Get Too Hyped About PP405. We've Seen This Movie Before.

       218 upvotes 1 year ago
      PP405 is a new hair loss treatment showing early promise with a 20% hair density increase, but skepticism exists due to past failures of similar treatments like Pyrilutamide, RU58841, and Bimatoprost. Users debate its potential effectiveness, with some hopeful due to Google's involvement, while others urge caution without more evidence.

      community How exactly is Eucapil (fluridil) approved in Europe?

      in Product  6 upvotes 3 years ago
      Hair loss discussion includes treatments like Minoxidil, Finasteride, and RU58841. Eucapil (fluridil) is approved as a cosmetic hair-care agent in Europe, but users question the level of testing required for approval.

      community Sugar and Hair loss connections

      in Research/Science  41 upvotes 1 year ago
      High sugar diets may worsen hair loss by increasing 5α-reductase activity and androgen levels, especially in women with PCOS. A low sugar diet might reduce scalp DHT levels, similar to finasteride, but genetics also significantly influence hair loss.

      community Hair regrowth after 8 months alhamdullah

      in Minoxidil  1415 upvotes 1 year ago
      A 30-year-old male saw significant hair regrowth after 8 months using minoxidil, finasteride, microneedling, and Nizoral shampoo. He experienced no side effects from finasteride and credited his success to this regimen.

      community Why you shouldn’t trust “progress” pictures.

      in Chat  388 upvotes 1 year ago
      Hair loss progress pictures can be misleading due to differences in lighting, hair length, and wetness, making it hard to accurately assess changes. Treatments mentioned include minoxidil and finasteride, with some users expressing skepticism about their effectiveness.

      community Shoutout to the mice that tested our Minoxidil

      in Satire  147 upvotes 1 year ago
      The conversation humorously acknowledges the role of mice in testing Minoxidil for hair loss while also discussing the ethics of animal testing. Some users argue against animal testing, citing cruelty, while others defend its necessity for medical advancements.

      community Turkey? Fin? Min? Fin+Min? Biotin? Keto? Saw? Dut? Nut?

       1350 upvotes 9 months ago
      Hair loss treatments and celebrity hair maintenance, mentioning finasteride, minoxidil, RU58841, biotin, ketoconazole, saw palmetto, dutasteride, and Nutrafol. The tone is satirical, speculating on celebrities' use of hairpieces and transplants.

      community Is this the maximum I can do for my hair without risking my manhood?

       17 upvotes 6 months ago
      A 23-year-old is using 2.5 mg dutasteride, 5 mg oral minoxidil, RU58841, a laser cap, and PRF injections for hair loss. They are hesitant about microneedling due to concerns about RU58841 absorption and are considering other treatments.

      community How many years can we expect PP405 to be on the market

       11 upvotes 1 year ago
      PP405 is expected to be on the market between 2027 and 2030, with phase 3 trials starting in 2026. There is skepticism about its fast-tracking due to its cosmetic nature, and it may appear on the gray market sooner.