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GlossaryNR3C1 gene (GR Gene)

encodes a receptor for stress hormones like cortisol

The NR3C1 gene, also known as the Glucocorticoid Receptor Gene, encodes a protein that binds to glucocorticoids, which are hormones involved in regulating metabolism, immune response, and stress. This gene plays a crucial role in how the body responds to stress and inflammation, and mutations or variations in NR3C1 can impact conditions like depression, anxiety, and autoimmune diseases.

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community Bryan (the guy who reversed aging) shares treatment that reversed his hair loss

in Treatment 1079 upvotes 1 month ago

A person improved hair loss from Norwood 3 to Norwood 2 using a topical formula with minoxidil, dutasteride, and tretinoin, plus oral minoxidil and red light therapy. There is skepticism about the treatment's effectiveness and concerns about misleading comparison photos.

community Fin+Min 1.5 years Progress. August 2020 – March 2022 20Yr old

in Progress Pictures 473 upvotes 2 years ago

User "burlysnurt" shares 1.5-year progress using Finasteride and Minoxidil for hair loss. Others congratulate and ask questions about the treatment, with "burlysnurt" sharing their routine and positive results.

community Are permanent hair gains even possible?

in Chat 14 upvotes 1 month ago

Hair regrowth from treatments like minoxidil, RU58841, and finasteride is not permanent; stopping these treatments typically results in hair loss resuming. Beard hair can become permanent with minoxidil use, unlike scalp hair, which requires ongoing treatment to maintain gains.

community Why is human evolution like this 😂

in Chat 2 years ago

Why androgenic alopecia affects the scalp rather than other body parts, potential explanations for this phenomenon, treatments available to combat hair loss, and the implications of male attractiveness in modern society.

community 4 months on 2.5 mg OM, no improvement

in Minoxidil 6 upvotes 1 year ago

After 4 months on oral minoxidil with no significant hair regrowth, a user is frustrated and considering alternative treatments since they can't take finasteride due to side effects. Suggestions include natural DHT blockers, lifestyle changes, and other hair care tips.

community Sandalore: a scientific homemade approch

20 upvotes 6 years ago

The post discusses using Sandalore as a potential hair loss treatment, emphasizing precise measurements and safe handling. The user compares Sandalore's effects to Minoxidil and mentions preparing a solution with ethanol and DMSO.

community DHT LEVEL IS 700pg/ml AFTER 8 MONTHS OF DUTASTERIDE

in Finasteride/Dutasteride 22 upvotes 2 months ago

The user had high DHT levels after 8 months on dutasteride, questioning the drug's authenticity. They got dutasteride from a legitimate source and will update on progress.

community GT20029 China Phase II Trial For AGA Reached Primary Endpoint

in Research/Science 134 upvotes 8 months ago

The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.

community Am I taking out too much foam for a dose? Rogaine Minoxidil

in Minoxidil 1 year ago

This conversation discusses the topical application of Minoxidil, with various users providing advice on how to accurately measure a dose and keep it from melting too quickly. Others have shared their experiences using oral finasteride for hair loss treatments.

community where does the renewed spironolactone hype come from?

in Research/Science 9 upvotes 2 years ago

Topical spironolactone is gaining attention as an alternative hair loss treatment, but it's not as effective as other options like finasteride. Oral spironolactone can cause side effects in men, and there are better topical alternatives like RU, Pyril, and CB.

community Another Creatine + Finasteride Experiment With Bloodwork

in Update 282 upvotes 2 years ago

Experimenting with the effects of creatine and finasteride on DHT levels, as well as a discussion regarding the potential link between creatine supplementation and hair loss.

community A meta analysis of 18 popular hair loss treatments. An 2022 guide on efficacy. From finasteride and minoxidil to caffeine shampoo, saw palmetto and biotin. 96 Scientific References included.

in Research/Science 101 upvotes 2 years ago

Most hair loss treatments are ineffective; only finasteride, dutasteride, and minoxidil show effectiveness.

community Roughly 4 months on the fin/min/microneedling combo.

in Progress Pictures 182 upvotes 1 year ago

A hair loss regime consisting of finasteride, minoxidil and microneedling that was started 4 months ago with minimal side effects reported. The user also uses Nizoral once a week.

community May have been mis-diagnosed for 10 years, self-investigation into AGA + AA Incognita (Defused Shedding)

in Treatment 1 upvotes 2 months ago

A 27-year-old male with AGA and diffused thinning has been using oral Minoxidil, Finasteride, Vitamin D, B12, Iron, and Ketoconazole shampoo. Despite a hair transplant and improved blood levels, he continues to experience hair loss and suspects a possible misdiagnosis of Alopecia Areata Incognita.

community Lab results from actifolic RU58841

in Product 39 upvotes 1 year ago

The post discusses the user's experience with hair loss treatment RU58841, which was tested for quality and found to be 96+% pure. The conversation includes various responses, with some users questioning the safety of the product and others expressing satisfaction with the test results.

community I’ve been using min and nizoral for 7 years, losing a lot of hair in the meantime. Here’s what happened when I added 1mg fin daily and 1.5mm micro needling weekly.

in Progress Pictures 212 upvotes 2 years ago

The positive effects of Finasteride, a hair loss treatment; and various other treatments such as Minoxidil and Nizoral that can be used to treat hair loss. Additionally, other methods are discussed, such as micro needling and taking spearmint supplements, which have been seen to help in some cases.