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GlossaryPolygenic Risk Score

numerical estimate of genetic predisposition based on multiple variants

A Polygenic Risk Score (PRS) is a numerical value that estimates an individual's genetic predisposition to a particular trait or disease, based on the cumulative effect of multiple genetic variants. By analyzing data from genome-wide association studies (GWAS), researchers can calculate a PRS to predict the likelihood of conditions such as alopecia, heart disease, or diabetes, providing valuable insights for personalized medicine and preventive healthcare.

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community Veradermics VDPHL01: why isn’t anyone talking about it?

in Treatment 31 upvotes 6 days ago

Veradermics' new hair loss treatment, VDPHL01, is likely a modified release oral minoxidil, which has received $75 million in funding for clinical trials. Despite skepticism about investing in a known treatment, some believe it could offer improved efficacy and reduced side effects.

community My strong recommendation for those shedding hair

in Treatment 92 upvotes 3 years ago

A user with aggressive male pattern baldness found that topical melatonin significantly reduced their hair shedding to 1 or 2 hairs per day and noticed some thickening of side hair. They tried many treatments like finasteride and minoxidil with little success, but topical melatonin showed immediate results in reducing hair loss.

community My Hairline journey. The first photo taken is the day I took the pill. No date specific just know I’ve been on finasteride 22 months. 2 years November 14th. ASK ANYTHING. Oh yeah started minoxidil a year later. Once every day or every other day super inconsistent and never really use 1ml, maybe half

in Progress Pictures 326 upvotes 2 years ago

. Fin from Inhouse This user has been taking finasteride for 22 months and minoxidil for 1 year to reduce hair loss, with apparent success; they have also avoided tight cornrow hairstyles to further protect their hairline.

community My Theory Regarding a Cause and Cure for Androgenetic Alopecia

in Treatment 97 upvotes 4 years ago

Hair loss theory suggests imbalance between Vitamin D Receptor (VDR) and Androgen Receptor (AR) activation. Proposed treatment includes upregulating VDR, downregulating AR, and improving mitochondrial health.

community Transient and Permanent Effects of Finasteride Use

in Research/Science 154 upvotes 3 years ago

Potential side effects of 5AR inhibitors like finasteride and dutasteride. Users debate risks, benefits, and personal experiences with these hair loss treatments.

community Anyone else realize how many younger guys are balding?

in Chat 262 upvotes 2 months ago

Many younger men are experiencing hair loss due to genetics, diet, stress, and lifestyle changes. Treatments like finasteride and minoxidil are mentioned, with some users noting improvements.

community Finasteride/dut. causes NAFLD,IR,diabetes,kidney dysfunction is it correct.

in Finasteride/Dutasteride 139 upvotes 1 year ago

Hair loss discussion mentions treatments like Finasteride, Dutasteride, and Minoxidil. Users share experiences, side effects, and advice on using these treatments.

community This is what Six years of DUT looks like

in Finasteride/Dutasteride 791 upvotes 1 year ago

User had success with dutasteride for hair loss after finasteride didn't work. Some experienced increased cholesterol and debated its relation to DHT.

community Finasteride, also known as Propecia or Proscar, treats male pattern baldness and enlarged prostate in millions of men worldwide. But a new study suggests the drug may also provide a surprising and life-saving benefit: lowering cholesterol and cutting the overall risk of cardiovascular disease.

in Research/Science 531 upvotes 9 months ago

The conversation discusses the potential benefits of finasteride (Fin) for lowering cholesterol and reducing cardiovascular disease risk, with users sharing personal experiences and opinions on the medication's effects on health and hair loss. Some users report positive changes in cholesterol levels after taking finasteride, while others are skeptical or joke about its effects.

community 57% increased chance of pattern hair loss independently associated with the consumption of sugary beverages in men (p<0.001) Pt 2

in Research/Science 479 upvotes 4 months ago

Sugary beverages increase the risk of pattern hair loss in men by 57%. Treatments discussed include Minoxidil, finasteride, and RU58841.

community Whats up with all the dutasteride destroying hair posts

in Finasteride/Dutasteride 64 upvotes 1 year ago

User Basic_Football999 discusses concerns about negative dutasteride experiences. Replies suggest dutasteride is effective, but some users may have issues with dosing frequency or genetic factors affecting results.

community Dermatologist told me to quit fin after turning 40

in Finasteride/Dutasteride 194 upvotes 1 year ago

A dermatologist advised a patient to stop taking finasteride (fin) after turning 40 due to potential risk of aggressive prostate cancer. The patient and others in the conversation debated this advice, discussing the relationship between finasteride, prostate cancer, and hair loss, and considering alternatives like topical finasteride.

community Dutasteride Vs. Testosterone, who wins?

in Finasteride/Dutasteride 58 upvotes 8 months ago

The conversation discusses whether 2.5mg of dutasteride or 200mg of testosterone weekly is more influential in preventing hair loss, with various personal experiences indicating that the effectiveness is dependent on the individual's genetic profile. Some users report that dutasteride is likely to be more effective at the given doses.

community Is someone like Elon Musk still on fin and min after hair transplant?

in Transplants 1 year ago

Hair loss treatments, specifically finasteride and minoxidil, being used by wealthy individuals to combat their genetic predisposition to baldness. It also discussed other potential treatments such as RU58841 and dutasteride.

community Diagnosed with MPB at 16 (Male)

in Treatment 55 upvotes 7 months ago

A 16-year-old diagnosed with male pattern baldness (MPB) was prescribed hair vitamins, vitamin D, a non-ketoconazole shampoo, and redenysl + serum, with a suggestion for GFC or IHRF treatments. Some users recommended minoxidil, ketoconazole, and derma stamping, while others advised against certain treatments until the age of 18.

community 5 month results on natural protocol, i made a post after 3 mont of treatment wich you can find in my profile. I used different massages(detumescence therapy, wooden brush, tom hagerty exercises)vitamins(d3,fish oil, biotin,msm, magnesium) drank green tea and ate pumpkin seeds( reduces dht)

in Is this regrowth? 146 upvotes 1 year ago

The user "Zealousideal-Pack340" shared their 5-month results on a natural hair loss treatment protocol, which included massages, vitamins, green tea, and pumpkin seeds. Some users suggested using medications like finasteride and minoxidil for better results, while others criticized the effectiveness of natural remedies. Overall, there was no clear consensus on the progress of the user's hair regrowth.

community 27yrs Balding since 16 , Progress (Fluridil , Pantostin ,Minoxidil,Stemoxydine,Microneedling,Nizoral)

in Progress Pictures 761 upvotes 8 months ago

A user has been experiencing hair loss since 2013 and has tried various treatments including finasteride, minoxidil, fluridil, pantostin, stemoxydine, microneedling, and Nizoral. They reported improvement after adding antiandrogens and other treatments in July of the previous year but stopped finasteride due to erectile dysfunction.

community Just popped my first fin, excited as hell!

in Finasteride/Dutasteride 154 upvotes 6 months ago

A user shared their excitement about starting finasteride for hair loss after trying various ineffective methods. Other users discussed their experiences with finasteride, including shedding phases and side effects, with one mentioning using topical finasteride and minoxidil.

community Found this meme on a forum……..

in Satire 150 upvotes 11 months ago

The conversation is about a meme related to hair loss that influenced someone to start taking finasteride. Another person agrees that the meme accurately represents the situation.

community 22M | 18 Weeks Progress | Very rapid and aggressive Hairloss since 17 and only learned about Min, Fin, etc. a few months ago | Words can't describe how happy I am with these results and the gains keep coming.

in Progress Pictures 92 upvotes 1 year ago

A 22-year-old man has seen significant improvement in his hair loss after 18 weeks using Minoxidil and Finasteride, starting treatment after rapid hair loss since age 17. He applies Minoxidil directly after an unspecified procedure, believing it's more effective and appreciates the sterilizing effect of the ethanol in it.

community Why is it so hard to select one

in Satire 641 upvotes 1 month ago

Choosing hair loss treatments is challenging due to concerns about side effects from finasteride and minoxidil. Users suggest starting with topical treatments and gradually increasing dosage, while some recommend oral finasteride for its effectiveness despite potential side effects.

community If you can give one advice to your younger self then what that would be?

in Research/Science 2724 upvotes 5 months ago

Users discussed hair loss treatments, specifically minoxidil and finasteride. They shared personal experiences and advice on starting these treatments early.

community Is anyone taking creatine while on fin and/or dut?

in Finasteride/Dutasteride 33 upvotes 5 months ago

The conversation discusses the use of creatine while on finasteride and/or dutasteride for hair loss. Opinions vary, with some users reporting no issues and others experiencing accelerated hair loss, suggesting effects are individual.

community Really stressed about my hair & so I am plannning to go with redensyl as against minoxidil

in Minoxidil 5 months ago

A user is considering using redensyl with procapil instead of minoxidil to reduce hair fall. They are stressed about hair loss and seek community feedback on these treatments.

community What hurts the most is that only minority of us are balding

in Chat 252 upvotes 1 year ago

The conversation discusses the emotional impact of early hair loss in men, with many feeling isolated and self-conscious. Some users also mention the lack of awareness about potential treatments like Minoxidil and Finasteride.

community 2 months fin, min, dermarolling, thoughts?

in Progress Pictures 149 upvotes 1 year ago

User shares 2-month progress with fin, min, dermarolling. Others discuss consistency, regrowth, shedding, and potential side effects.

community How to prevent hair loss while taking creatine?

in Research/Science 4 upvotes 4 months ago

A user is concerned about hair loss from creatine and asks for precautions, mentioning treatments like Minoxidil, finasteride, and ketoconazole shampoo. Replies vary, with some users sharing personal experiences and others dismissing the concern.

community Androgenetic alopecia - I want your honest opinion

in Female 33 upvotes 2 years ago

A female user's diagnosis of androgenetic alopecia, and the advice shared in response which suggests taking spironolactone and minoxidil together to prevent hair loss.

community On Fin 5 days a week and dut twice a week and still rapidly losing hair. HOW?? 9 months on fin!

in Finasteride/Dutasteride 25 upvotes 2 years ago

A user using finasteride and dutasteride to treat hair loss, but still losing hair rapidly after stopping minoxidil. Replies suggest that the user should try oral minoxidil or switch to dutasteride for better results.

community Are they going to Ban Finasteride in the EU ?

in Finasteride/Dutasteride 68 upvotes 2 months ago

There is concern about a potential ban on finasteride in the EU, but many believe it is unlikely unless serious side effects are found. Users rely on finasteride for hair loss and other health benefits, and a petition has been created to oppose any restrictions.