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      community Anyone tried Dr. Rassman's topical Finasteride? Is it liposomal?

       7 upvotes 6 years ago
      The conversation discusses concerns about Dr. Rassman's topical Finasteride, specifically whether it is liposomal or glycol-based. Dr. Rassman insists on providing the correct liposomal formulation and urges patients to contact him if they receive the wrong product.

      community The mystery of Azelaic Acid

       5 upvotes 11 years ago
      The conversation discusses using Rogaine (Minoxidil) and ketoconazole for hair regrowth, with interest in trying a formulation with Azelaic Acid for potentially better results. Concerns about Azelaic Acid's effectiveness and safety, including skin sensitivity to sunburn, are mentioned.

      community Novel effect of sildenafil (cialis) on hair growth

       19 upvotes 4 years ago
      Sildenafil (Viagra) shows potential for hair growth by enhancing dermal papilla cell proliferation and stimulating perifollicular vessel formation. Users discuss the possibility of using Cialis (tadalafil) similarly, noting its benefits and side effects.

      community Does topical Finasteride look milky?

       1 upvotes 2 days ago
      Topical finasteride should not appear milky; it seems the pharmacy may have used crushed pills instead of pure powder. It's advised to return the product and seek a better formulation from another pharmacy for optimal results.

      community Bloodwork on 0.5mg dutasteride

       4 upvotes 2 days ago
      The conversation discusses using 0.5mg dutasteride for hair loss and the decision to switch back to finasteride pills due to insufficient suppression. It highlights the importance of drug formulation and potential issues with absorption or degradation.

      community Anagen (@anagenxyz) claiming they've cracked scalp-only DHT blocking - thoughts?

       15 upvotes 4 days ago
      A company is developing a topical dutasteride that targets hair follicles without significantly affecting systemic DHT levels, with trials underway to measure its effectiveness. Users discuss the potential benefits and skepticism around the formulation compared to existing treatments.

      community Let's settle the debate dut pill or tablet

       1 upvotes 1 week ago
      Dutasteride tablets are effective for hair loss, with dosage control being an advantage over capsules. Both tablets and capsules are used, but formulation quality is crucial for effectiveness.

      community Where are you guys getting topical Dutasteride in the U.S.?

       5 upvotes 3 weeks ago
      The conversation discusses sourcing topical Dutasteride in the U.S., with mentions of avoiding Hydrocortisone and suggestions like Xyon and Maximus. Users also mention Happy Head for custom formulations.

      community Is it even possible to lose ground on Dutasterid?

       15 upvotes 1 month ago
      Dutasteride can maintain or regrow hair in about 92% of users, but some still experience hair loss. Topical formulations and dosage frequency are discussed, with some users reporting side effects and switching treatments.

      community Why you can still look forward to PP405 and JXL-069

       22 upvotes 1 month ago
      PP405 and JXL-069 are the same compound, but users experienced no results due to flawed application methods. The topical gel formulation of PP405 is designed to target hair follicle stem cells effectively, unlike liquid solutions that fail to penetrate deeply.

      community Are PP405 and JXL069 the same ?

       2 upvotes 1 month ago
      PP405 and JXL069 are the same active molecule, suvomipic, but differ in effectiveness due to delivery methods. Grey market versions fail due to improper formulation and stability issues, unlike the clinically engineered Pelage Pharmaceuticals version.

      community 14 months on Fin, Total T 899, serum DHT 276 — high total T may still drive scalp DHT even when blood levels look controlled

       3 upvotes 4 months ago
      A 23-year-old male has been using finasteride and topical minoxidil for 14 months with slight improvement, but recent shedding led him to switch to a new minoxidil formulation without success. He is considering using topical RU58841 or dutasteride to better address scalp DHT, as his bloodwork shows high total testosterone and mid-range DHT levels.

      community Handle the itch from Minoxidil?

      in Minoxidil  1 upvotes 5 months ago
      Minoxidil can cause scalp itchiness, often due to propylene glycol, and users suggest alternatives like foam formulations without PG, using moisturizing oils, or reducing application frequency. Some recommend ketoconazole or zinc pyrithione shampoos to help with inflammation and itchiness.

      community Has anyone gotten pp405 on the grey market yet?

      in Research/Science  10 upvotes 5 months ago
      People are discussing the use of an untested hair loss treatment called PP405, which is not available on the grey market. Some users are trying a mimic formulation called HP3, reporting thicker hair but no new growth yet.

      community CRAZY HIGH? 1% Fin 0.3% GHK-CU topical perscription

       2 upvotes 6 months ago
      The conversation discusses concerns about using a high concentration of 1% topical finasteride for hairline balding, with some users suggesting starting with a lower dose. It also mentions the use of GHK-CU peptide and the importance of considering the formulation to avoid excessive absorption.

      community Homemade topical dutasteride/finasteride

       4 upvotes 9 months ago
      The conversation discusses making homemade topical solutions of dutasteride or finasteride using tablets, with suggestions to use alternatives like MinoxidilMax or stemoxydine due to difficulties in formulation. Some users recommend sticking to oral pills for effectiveness and ease.

      community So was the Grey Market Breezula fake all along?

       5 upvotes 9 months ago
      Breezula's effectiveness may depend on the vehicle used for its application, with concerns about the grey market version's formulation. Phase 3 results are promising, but skepticism remains about the grey market product's authenticity and effectiveness.

      community Method for creating 0.01% duta topical solution, will this work?

      in Microneedling  4 upvotes 10 months ago
      The conversation discusses creating a 0.01% topical dutasteride solution mixed with minoxidil for hair loss treatment, with concerns about absorption and effectiveness. Some users suggest that dutasteride needs specific formulation for better absorption, while others recommend oral use for practicality.

      community Possible natural pp405 solution

      in Research/Science  45 upvotes 1 year ago
      Rotenone, a natural plant extract, may promote hair growth by increasing LDH activity and blocking MPC in the scalp, but it carries risks due to its toxicity. The suggested formulation includes Barbasco extract, DMSO, propylene glycol or PEG-400, ethanol, and a carrier oil.

      community New warning by FDA on topical finasteride

      in Research/Science  194 upvotes 1 year ago
      The FDA warned that topical finasteride can cause serious side effects like sexual dysfunction and brain fog, similar to oral finasteride. Compounded topical formulations pose additional risks due to lack of regulation.

      community Thoughts on 5% Topical Minoxidil with 0.01% Tretinoin serum

       3 upvotes 1 year ago
      The conversation discusses using a 5% Topical Minoxidil with 0.01% Tretinoin serum for hair loss, noting its lack of propylene glycol to avoid itchiness and greasiness. Users share experiences with different Minoxidil formulations and discuss the effectiveness and stability of Tretinoin in various forms.

      community Topical Finasteride that doesn’t go systematic is the cure

       3 upvotes 1 year ago
      Topical finasteride that doesn't penetrate the skin could potentially treat hair loss without side effects. Current challenges include finding a formulation that remains on the scalp without increasing blood levels.