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TWIST-1 gene's role in hair loss and potential as a treatment target. Inhibiting TWIST-1 may prolong hair growth and reduce hair follicle sensitivity to DHT.

The conversation discusses why DHT (dihydrotestosterone) negatively affects scalp hair but promotes growth elsewhere on the body. Various opinions include genetic predispositions, differences in hair follicle reactions to DHT, and the potential role of Omega-3 in reducing inflammation and promoting hair health.

The conversation discusses using microneedling combined with castor, peppermint, rosemary oils, and caffeine as a treatment for mild hair loss, aiming to stop or slow down hair loss and potentially regrow hair. The effectiveness of this treatment without side effects is uncertain, and it may slow hair loss but results vary.

The user discusses using dutasteride to stop hair loss and bimatoprost for regrowth. They plan to use VEGF with hydrogels for potentially permanent hair follicle improvement and suggest PRP as an alternative.

The user reported progress with hair regrowth using a topical solution combining finasteride and minoxidil, but experienced scalp irritation which improved after adjusting the treatment. They are considering microneedling but are concerned about the risk of scarring.

Testosterone within the normal range does not significantly contribute to male pattern baldness (MPB); DHT is the main factor that can be controlled. Genetics play a crucial role in hair loss, and treatments like finasteride and dutasteride, which block DHT, can help despite potentially raising testosterone levels.

Dutasteride at 2.5mg is considered a potential hair loss cure due to its DHT-blocking ability, but there are concerns about side effects and individual responses. Minoxidil, finasteride, and RU58841 are also discussed, with mixed opinions on their effectiveness and safety.

The conversation discusses affordable hair loss treatments, including topical finasteride, minoxidil, tretinoin, and natural remedies like castor and peppermint oil. Specific treatments for hair loss are the focus.

Hair loss treatments discussed include minoxidil, finasteride, dutasteride RU, derma rolling, pyrilutamide, cosmeRNA, hair systems, and essential oils. The user seeks information on additional treatments, safety profiles, and alternative options for androgenetic alopecia.

A user shared their positive experience with Roots by GA, a company that creates personalized hair loss treatments based on DNA analysis, which confirmed their inability to tolerate finasteride. The user is satisfied with their progress 30 days after a hair transplant and the customized formula they received.

David Lynch is remembered for his impressive hairline, sparking discussions about genetics and hair loss. Users humorously speculate on hair loss treatments and genetics, mentioning names like Minoxidil and finasteride.

A user suggests that deeper microneedling with Verteporfin injections might help regrow hair in areas with scar tissue, alongside a DHT blocker. Another user explains that hair loss might be due to reduced Wnt/β-Catenin signaling and suggests that treatments like Minoxidil, Finasteride, and microneedling could potentially reverse it.

Scientists discovered a sugar gel, 2dDR-SA, that increased hair growth in mice. Users discussed its potential, comparing it to other treatments like Minoxidil and finasteride.

A man has been using finasteride for almost 11 months to treat hair loss and has seen significant improvement without noticeable side effects. Other users are discussing starting finasteride, sharing their own experiences, and asking about the timeline for visible results.

People who experience diffuse thinning of their hair and how they cope with going swimming. People discussed wearing a swimming cap, making jokes out of it and accepting that it's genetics.

Hair loss, which is sometimes accompanied by itching. Treatments discussed include Minoxidil, finasteride, RU58841 and ketocazole shampoo.

A user who got a hair transplant and gave their experience with it, including how the donor area recovered quickly and the potential risks of getting a hair transplant at a young age. Other users discussed bleaching and dyeing transplanted hair, as well as asking about the clinic where the procedure was done.

A 50-year-old Black woman with alopecia areata and traction alopecia is seeking a science-based hair loss routine. Current treatments include spearmint tea for DHT levels and considering PRP.

Hair loss itch is caused by DHT attacking follicles and stimulating nerves. Finasteride users who respond well don't experience this itch.

User discusses hair loss and treatments, including Minoxidil, finasteride, and RU58841. Concealers like dermamatch help improve appearance of hair thickness.

Poor diet and lifestyle contribute to male pattern baldness. Treatments like Minoxidil, dietary changes, and lifestyle adjustments may help slow hair loss.

Minoxidil alone may not stop hair loss. Finasteride is recommended for androgenic alopecia, as minoxidil doesn't prevent DHT from miniaturizing hair follicles.

HairClone is developing cell replacement treatments to rejuvenate and generate hair follicles, and has launched a crowdfunding campaign. A user expressed skepticism about the need for crowdfunding.

User took 2.5 mg oral minoxidil, saw hair growth but stopped due to excessive body hair. Recently started finasteride and plans to update progress.

Minoxidil-dependent hairs fall out if minoxidil is stopped. New treatments like GT20029, FOL055, or TDM105795 might help sustain these hairs.

A user's results with taking finasteride and minoxidil to treat hair loss, which have been successful after three months. Replies discussed dosage information, as well as providing congratulations and astonishment.

2 Deoxy D Ribose may promote hair growth and aid wound healing, potentially enhancing microneedling effects. Users discuss its combination with microneedling for better hair growth results.

Fluridil may decrease the number of androgen receptors in hair follicles by up to 95%. This suggests a different action mechanism from other non-steroidal antiandrogens like RU58841, indicating they might be used together.

A user is excited about scheduling a hair transplant for July 1st, after 2 years of using Minoxidil, finasteride, and RU58841 with no regrowth. The transplant will cost €2500-€3000 for 1000-1200 grafts, and the user chose to have it done locally rather than traveling abroad to save money.

After 11 years on Finasteride, a user's hair is thinning again, suggesting hair may become more sensitive to DHT with age. They plan to introduce Dutasteride once a week, as they cannot tolerate Minoxidil.