A 27-year-old male experienced rapid hairloss after dengue fever, which activated a balding gene. The doctor suggested platelet-rich plasma treatment for hair regrowth.
Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hairloss by blocking DHT and promoting hair growth.
A 48-year-old man has been using minoxidil for 15 years and considered finasteride but stopped due to potential side effects. He is concerned about his mental health and the impact of hairloss on self-image, and he encourages support among men experiencing hairloss.
The user has been on finasteride for over four years without noticeable results and recently added dutasteride and RU58841, but continues to experience hairloss. They are considering stopping all medications due to lack of effectiveness and side effects like extremely dry eyes from dutasteride.
The user experienced concerning side effects like throat irritation, shortness of breath, chest pain, and testicle pain after using RU58841 for hairloss, despite also using finasteride and minoxidil. Other users shared mixed experiences, with one advising to stop using RU58841 due to similar side effects, while another reported significant hairloss reduction without side effects.
A user experienced heart problems after taking 1mg finasteride and 2.5mg oral minoxidil and is considering quitting minoxidil. Others discussed their experiences with heart issues and minoxidil, with some suggesting topical minoxidil as a safer alternative.
The conversation discusses the effectiveness of anti-androgens for hairloss, with a preference for topical treatments like RU58841 over oral options due to better scalp concentration and fewer side effects. Topical finasteride at 0.1% may provide some results, especially when combined with a topical androgen receptor antagonist like RU58841.
The conversation highlights the general public's lack of knowledge about hairloss, with various ineffective remedies suggested, such as not wearing hats or using hair fibers. The only effective treatments mentioned for male pattern baldness are medications like minoxidil and finasteride, and hair transplants.
The conversation discusses hairloss and treatments, with users suggesting the original poster's hair has receded despite using a dermaroller and RU58841 for two months. Many recommend starting finasteride and minoxidil for better results.
A user on dutasteride and oral minoxidil for two years reports worsening hairloss and is seeking advice. Suggestions include consulting a professional for underlying causes, acknowledging that treatments don't work for everyone, and considering dosage adjustments or additional treatments.
Dutasteride is less commonly prescribed for hairloss because it is not FDA-approved for this purpose, unlike finasteride, which is more accessible and preferred due to fewer side effects. Dutasteride may be more effective in reducing DHT but has a longer half-life and potentially more significant side effects.
The conversation discusses the potential benefits of topical caffeine for Androgenetic Alopecia (APA) and female pattern hairloss. While some studies suggest positive results, there's no reliable scientific evidence to strongly recommend caffeine compounds for hair regrowth.
Potential side effects of 5AR inhibitors like finasteride and dutasteride. Users debate risks, benefits, and personal experiences with these hairloss treatments.
User discusses hair regrowth using RU58841, minoxidil, and dutasteride. Many users praise the progress and ask about the treatments' effectiveness and side effects.
User Wonderful_Tonight910 suffered from hairloss and seborrheic dermatitis for years. After using irritant-free shampoo, their scalp improved, hairloss stopped, and new hair growth appeared.
The conclusion of the conversation is that some individuals may experience a condition called reactionary hypergonadism when taking dutasteride for hairloss. This condition can lead to an increase in testosterone levels, which may worsen hairloss instead of improving it.
The conversation discusses the use of dutasteride (DUT) versus finasteride (FIN) for hairloss treatment, with some users preferring DUT for its effectiveness while others choose FIN due to its approval status, better long-term data, and lower risk of side effects. Users share personal experiences with both medications, including side effects and effectiveness.
Scalp biopsies are crucial for diagnosing hairloss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hairloss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.
The post discusses frustration over the limited and not always effective treatments for hairloss, mainly Minoxidil and Finasteride. The conversation includes mentions of potential new treatments like GT20029, HMI-115, CosmeRNA, KX-826, and microneedling, but also highlights the challenges of funding and prioritizing research in this area.
A 24-year-old male is considering the "Big 4" treatments (Finasteride, Minoxidil, Ketoconazole shampoo, and Microneedling) or a hair transplant for hairloss. Most users recommend starting with Finasteride and Minoxidil to stabilize hairloss before considering a transplant.
The conversation discusses whether it's better to start hairloss treatment with finasteride or dutasteride. Opinions vary, but many suggest starting with finasteride due to its shorter half-life and easier management of side effects, while others argue dutasteride is more effective and has fewer side effects.
Pyrilutamide, a potentially effective hairloss treatment; other topical treatments like RU58841 and CB-03-01 that may have fewer side effects than Pyrilutamide; and the Phase 3 clinical trials of Pyrilutamide, which is likely to be approved by the FDA soon.
The user shared their personal experience with hairloss, hormone imbalances, and treatments including testosterone boosters, natural estrogen blockers, and DHEA. They suggest that low-dose finasteride and natural hormone therapy could reduce hairloss with fewer side effects.
Natural remedies to treat hairloss, such as polyphenols, apple peel extract, grape seed extract, green tea extract, peppermint oil, pumpkin seed oil, apigenin, Ginkgo biloba, red clover extract, olive leaf extract, Ecklonia Cava and Grateloupia elliptica. In addition, terpenes, carotenoids, and tocopherols were discussed as potential treatments.
The conversation discusses the effectiveness of finasteride and dutasteride in treating hairloss, emphasizing that significant results often take 12-18 months or more. Dutasteride is generally considered superior, with similar or fewer side effects than finasteride, but patience is required for noticeable improvement.
The group buy for CB-03-01, a topical anti-androgen for hairloss, was postponed and refunded due to issues with the product's form and solubility. The product, also known as Breezula, is an alternative to finasteride with fewer side effects, but its official release is delayed until 2021.
A 28-year-old started using finasteride and minoxidil for hairloss and is frustrated by insensitive comments from others about his balding, which is a sensitive topic for him. People, including a girl he's seeing, have made hurtful remarks, and the conversation includes discussions on societal double standards and advice to ignore such comments and focus on self-improvement.
This conversation is about hairloss treatments, specifically oral minoxidil and finasteride. Users discussed the potential side effects of using these drugs, as well as their experiences with them.
Hairloss treatments, specifically 5AR inhibitors, can impact neurosteroids and sexual health. The effects of topical fin/dut on tissue-specific DHT levels are unclear.
A user is struggling with hairloss at 17 and has been using finasteride for 5 months and minoxidil for 11 months without seeing regrowth. Other users encourage continuing treatment, sharing their own experiences with finasteride, minoxidil, and dermarolling, and emphasizing patience and acceptance.