RU58841, a potential hair loss treatment, was not commercialized due to marketability issues and lack of long-term safety data. Concerns about its formulation and delivery methods further complicate its use.
Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.
User Wonderful_Tonight910 suffered from hair loss and seborrheic dermatitis for years. After using irritant-free shampoo, their scalp improved, hair loss stopped, and new hair growth appeared.
How little the average person knows about hair loss and how it can be an unfairly stigmatized issue, even by people with little knowledge of it themselves. Some specific treatments that were discussed include finasteride, RU58841, dutasteride, minoxidil, pyritinol, dermarolling, and diet/lifestyle changes.
A user's progress with treating hair loss over 3.5 months, which involves taking finasteride MWF, minoxidil daily and microneedling once a week. There was positive feedback from other users regarding the results.
Quitting vaping significantly reduced hair loss for a user who was a heavy vaper and also taking finasteride. Some participants suggest nicotine's vasoconstrictive properties may worsen hair loss, while others share personal anecdotes of hair improvement after quitting smoking or vaping.
The conversation discusses the potential of long-chain unsaturated fatty acids, like oleic and linoleic acid, as an additional treatment for hair loss, which may inhibit the enzyme responsible for converting testosterone to DHT and promote hair growth. Users humorously suggest using oils topically and discuss other hair loss treatments, but the main focus is on the science behind fatty acids and their role in hair health.
A user discusses starting nandrolone replacement therapy to stop hair loss and improve hair health, noting its benefits over finasteride. They report halted hair loss, improved skin, increased muscle, and a calm mood after three weeks.
Whether Finasteride can keep alive the hair gained by Minoxidil after quitting it, and why beard hairs are not as susceptible to miniaturization. It is suggested that scalp hair may be dependent on Minoxidil and that DHT could be countered with Finasteride to some extent, but there is no definitive data proving this.
Dutasteride promotes more hair regrowth than Minoxidil. Users discuss combining treatments for better results and share personal experiences with side effects.
Minoxidil effective for regrowth but causes dryness; finasteride stops hair loss but may affect hormones; dutasteride powerful but reduces libido; RU58841 thickens hair but expensive and risky; dermarolling improves blood flow and results; aminexil overrated and not effective. Dermarolling beneficial with both minoxidil and finasteride.
A user who was losing their hair and found an effective solution; they asked for opinions on it and discussed treatments such as Minoxidil, Finasteride, and RU58841, as well as SMP.
User "likitiiki" shared 8-month progress using only Finasteride for hair loss. Many users praised the results, while others discussed their own experiences and dosages.
A user named "LordGeek101" shared their positive experience with hair regrowth after using 5mg of finasteride daily, 5% minoxidil twice daily, and hormone replacement therapy (HRT) for 8 months. The user is transgender (MTF) and mentioned that the larger dose of finasteride was recommended by their doctor for better chances of hair revival.
User Tricky9555 tried various hair loss treatments for 8 months with no visible results. Others suggested considering a hair transplant, checking thyroid levels, and being patient for up to 24 months for potential results.
A 20-year-old is experiencing hair loss despite using dutasteride and oral minoxidil. Suggestions include consulting a specialist, considering RU58841, and checking for other conditions and vitamin deficiencies.
The conversation discusses hair regrowth progress from Norwood scale 4 to 2.5 over a year using daily 8.5-9% RU58841, topical Dutasteride 0.1%, RU58841 5% 1.5 times a week, and daily caffeine redensyl scalp treatment.
The user is discouraged after nearly a year of using oral minoxidil and dutasteride without seeing desired hair regrowth. Suggestions include increasing dutasteride dosage, trying hair transplants, and considering other treatments like derma stamping or topical solutions.
A user sharing their progress after using Fin, Minoxidil, keto diet, and microneedling for two months to attempt to regrow hair on bald temples. Other users replied with advice and support.
The user reported early stage diffuse hair thinning and increased DHT levels after 4 weeks on Finasteride and 8 weeks on Finasteride plus 4 weeks on Dutasteride, despite the medications being authentic and stored properly. They are considering increasing their Dutasteride dosage due to the lack of side effects and are unsure if the treatment is helping their hair.
The conversation discusses a user's experience with hair loss treatments, specifically using finasteride for almost 5 months and minoxidil for 8 months. The user is considering switching to oral minoxidil and possibly dutasteride if not satisfied with the results, despite others noting progress and advising patience.
A 22-year-old is experiencing significant hair shedding and is using multiple treatments, including oral and topical minoxidil, finasteride, topical dutasteride, ketoconazole shampoo, and considering adding RU58841 and stemoxydine. Others advise patience, suggesting sticking to finasteride and minoxidil for at least a year before evaluating results, as initial shedding is normal and adding too many treatments can be counterproductive.
The user "PowerfulAide6677" shared progress pictures of their hair loss journey, mentioning that they have been on finasteride for 8 years and are considering adding oral minoxidil to fill in their hairline. Some users advised against adding oral minoxidil, suggesting that the user's current maintenance with finasteride is sufficient.
Hair loss treatments, such as minoxidil, finasteride, microneedling, ketoconazole shampoo and vitamins D3 and Omega 3, which appear to have been successful in regrowing hair on a user's temples that had been slick bald for 8-9 years.
The user reports significant hair density improvement after 8.5 months of using finasteride, with no side effects except for initially watery semen. They also mention increased sex drive, which they attribute to finasteride, and regret not starting the treatment earlier due to fear of side effects.
A 32-year-old male with diffuse thinning and seborrheic dermatitis has been using finasteride for 8 months without improvement. He is considering COQ10 + PQQ supplements for scalp inflammation and hair loss.
OP is trying various treatments (finasteride, minoxidil, nizoral, dermarolling, tretinoin) to regrow hair after 8 years of baldness. Users suggest persistence and possibly adding dutasteride, noting that age and consistency affect results.
A user has been using oral finasteride and minoxidil without significant hair regrowth and is questioning the effectiveness of adding microneedling to their routine. Another user suggests microneedling can help with topical treatments but doesn't see it as a major factor in improving hair loss.