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Finasteride is metabolized in the liver and excreted through urine and feces. Users humorously discuss its excretion, with one joking about it being expelled through ejaculation.

Some individuals do not respond to oral minoxidil for hair loss, despite it generally working by improving blood flow to hair follicles. Factors like metabolism, drug interactions, and individual variations in the drug's activation may influence its effectiveness.

Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

The conversation is about people with advanced hair loss (Norwood 6 or 7) who have seen significant hair regrowth using treatments like finasteride, minoxidil, microneedling, and RU58841. Nine cases were collected to motivate others to try these treatments despite advanced hair loss.

A user experienced hair regrowth after 6 months on finasteride, which is earlier than the usual 12-18 months observed by their dermatologist. The dermatologist noted this as an exceptionally good response.

A user shared a 3-month hair regrowth transformation using Finasteride 1mg, Minoxidil, and occasional derma rolling. Some responders are skeptical of the rapid growth, while others suggest the user might be an exceptional responder to the treatment.

A user is experiencing genetic hair loss and is using spironolactone and minoxidil without success. They are considering switching to vegan protein powder due to digestive issues and are concerned if it will worsen hair loss.

A user has been on 1mg finasteride daily for 10 months, initially seeing great results, but started shedding heavily again at the 7-month mark. They are considering whether to continue with finasteride or switch to dutasteride.

Hair loss treatments vary greatly in effectiveness and timelines, with no guaranteed results. Common treatments mentioned include finasteride, minoxidil, and RU58841.

The conversation discusses hair loss treatments, specifically mentioning Minoxidil, finasteride, and RU58841. It also touches on a study involving zinc and L-arginine.

The conversation humorously discusses using finasteride to combat hair loss, referencing "Dune" themes. Users agree that finasteride is essential for maintaining hair.

The user discusses switching from multiple vitamins to a single multivitamin pill. They also mention using oral finasteride and topical minoxidil with finasteride for hair loss treatment.

A user shared their hair regrowth progress after using 1mg of finasteride daily for six months, with a break of two weeks due to knee surgery. Some suggest adding minoxidil for better results, while others discuss finasteride's effectiveness in promoting hair growth, which can be slower but significant.

A 48-year-old who had been thinning since 25 and reached NW4-5 baldness saw no improvement with 1mg/day finasteride and 5% minoxidil twice a day after 8 months. After copying another person's routine, they now use 0.5mg finasteride, ketoconazole shampoo weekly, daily microneedling with 0.5mm and 1mm once a week, and apply minoxidil twice daily, resulting in baby hairs on their bald spot and temples after three months.

A user experienced increased hair fall after starting Minoxidil tablets, despite following a comprehensive treatment plan for Seborrhoeic Capitis and Androgenetic Alopecia. They are unsure if the Minoxidil tablets are the cause and seek advice.

The conversation discusses a leave-in ketoconazole product for hair loss, which is not commonly mentioned like Nizoral shampoo. One reply suggests it acts similarly to finasteride but with potential for low absorption and similar side effects.

A user shared an 8-month hair regrowth progress using finasteride, topical minoxidil, and microneedling, and others reacted positively, asking for details about the treatment regimen. The user also mentioned taking cod liver oil and a hair multivitamin with biotin and collagen.

A group buy for hair loss treatments including Harmine 19a, TM5614, Abiraterone Acetate, and others. A compound, BMS-202, that can potentially reverse gray hair is also mentioned.

The conclusion of the conversation is that the user, PirateBeastBaby, had good results with microneedling for hair loss after using oral finasteride and topical minoxidil 20 years ago. They believe that microneedling was the gamechanger for their hair growth.

User had a hair transplant in 2016 but stopped taking finasteride due to side effect concerns. Now considering another transplant and starting finasteride, minoxidil, and microneedling to improve hair situation.

A user's results after using finasteride (1.25mg/day) for one year, which included improvements to their hair and skin as well as some side effects such as decreased libido and watery semen. They also mentioned they stopped taking creatine around the same time.

The user treated their hair loss with microneedling, nanoxidil, rosemary oil, jojoba oil, scalp massages, keto shampoo, and supplements. They experienced significant hair regrowth and a reduction in hair shedding within 8 weeks.

The user healthydudenextdoor starting a new topical anti-androgen hair loss treatment, Pyrilutamide, and discussing their current regimen of finasteride and minoxidil.

Hair cloning is discussed as a potential future solution for hair loss, but it's not expected to be available soon due to high costs and technical challenges. Current treatments like Minoxidil, finasteride, and RU58841 are not mentioned in this conversation.

The user experienced side effects commonly attributed to Finasteride without ever taking the drug, suggesting these issues may stem from other life factors. They advise considering other potential causes before blaming Finasteride for such side effects.

A 23-year-old male has been using finasteride, dutasteride, and drinking topical minoxidil for almost four months to combat hair loss, seeing reduced shedding and some regrowth. Users advise against drinking minoxidil and suggest that using both finasteride and dutasteride together is overkill.

Men wearing wigs should be normalized as it is for women. Treatments like Minoxidil and finasteride are mentioned, but societal norms need to change to accept wigs for men.

A 24-year-old shared his 11-month hair regrowth progress using 1mg oral finasteride, Dr. Reddy's Minoxidil + Finasteride 5% topical solution, 2.5 mg oral minoxidil, microneedling, ketoconazole shampoo, and plans to switch to dutasteride and tretinoin. Users praised his progress, discussed hair regrowth strategies, and shared personal experiences with hair loss treatments.

OP shared an 8-month update on hair transplant results, using Dutasteride, oral Minoxidil, and Biotin. OP also discussed a simple skincare routine with Cerave products and sunscreen.