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      community PP405 Hairloss Reversal and Hairline Restoration

       5 upvotes 7 months ago
      PP405 may induce new hair growth but cannot revive completely dead follicles, and its effectiveness on hairlines is uncertain. It is expected to be available by mid-2028, but users are advised to manage expectations and consider using other treatments like minoxidil and finasteride.

      community Update progress on Fin, Min, and Kx-826

       8 upvotes 1 year ago
      The user is using oral finasteride, minoxidil, and KX-826 for hair regrowth, noticing small improvements. They plan to add ketoconazole shampoo and consider a hair transplant with verteporfin after a year of treatment.

      community Terrible experience with MV Supplements and no support

       4 upvotes 2 years ago
      A user had a bad experience with MV Supplements when their Pyril powder and ethanol order leaked during shipping, making the products unusable. Despite contacting support and providing evidence, the company's return policy did not allow for a refund or replacement.

      community Does anyone here use MVSupplements.con products?

       1 upvotes 11 months ago
      The conversation discusses concerns about MVSupplements.com products, specifically the Min+Ru spray and GHK Serum, due to discrepancies in ingredient lists and recent poor feedback. Users also mention a price increase and one user reports no issues with the RU powder.

      community 5 months top fin/min.. finally some slight progress?

       41 upvotes 4 weeks ago
      The user has been using Hims spray with Minoxidil and Finasteride for 5 months, along with derma rolling and ketoconazole shampoo, and is seeing slight hair regrowth. They are advised to continue the treatment and consider a hair transplant in the future.

      community 15 Months Ago vs 15 Minutes Ago (Fin + Min + Spiro + E)

       43 upvotes 2 months ago
      The user experienced significant hair regrowth using spironolactone, estradiol, minoxidil, and finasteride while transitioning. They noted reduced libido and increased grogginess as side effects.

      community High estradiol from finasteride

       3 upvotes 4 years ago
      The user experienced high estradiol levels and side effects after stopping finasteride and is concerned about whether these hormonal imbalances are temporary. They are seeking advice on reversing the condition without starting new treatments due to hypersensitivity to finasteride.

      community 5 weeks Min + vit D/Zinc/biotin/collagen progress

       5 upvotes 3 years ago
      The user is using Minoxidil, vitamin D, zinc, biotin, collagen, and micro-needling for hair regrowth. Some users suggest biotin and collagen are ineffective and emphasize the need for a DHT blocker for lasting results.

      community A warning to anyone considering 3rd party sourcing PP405 or its analogs

       30 upvotes 5 months ago
      Be cautious when sourcing PP405 or its analogs from third-party suppliers due to potential safety risks and lack of regulatory approval. The conversation highlights concerns about counterfeit products and the absence of reliable testing, making it risky to use such treatments.

      community So I hacked the AAD 2026 live stream

       42 upvotes 5 months ago
      The conversation discusses a live stream presentation on Pelage PP405 for hair regrowth, with skepticism about its effectiveness compared to minoxidil. Some users express doubt and suggest sticking to proven treatments like minoxidil, finasteride, and RU58841.

      community Very exited about Veradermics,

      in Research/Science  29 upvotes 4 months ago
      Veradermics is a promising new treatment for hair loss, essentially a repackaged version of Minoxidil. The user is optimistic about its potential effectiveness.

      community KX826 New Phase 3 Trial In China for 2025: 1.0% concentration

       62 upvotes 1 year ago
      KX-826 is undergoing Phase III trials in China as a potential treatment for male pattern baldness, with some users considering it as an alternative or addition to finasteride and dutasteride. Opinions on its effectiveness vary, with some users reporting positive results and others finding it expensive and ineffective.

      community 5 year update on Finasteride and Minoxidil

       418 upvotes 1 year ago
      The user has used finasteride and minoxidil for five years to slow hair loss but hasn't seen regrowth. They are considering increasing finasteride dosage, switching to dutasteride, and exploring microneedling and oral minoxidil.

      community Update for PP405 - phase 2b underway

       122 upvotes 1 year ago
      PP405 is advancing to Phase 2b trials, showing promise from Phase 2a. It may be available in 3-6 years, with trials using a topical gel.

      community Am I missing something with pp405?

       34 upvotes 1 year ago
      PP405 is discussed as a potential hair growth stimulant, possibly more effective than minoxidil, but not a cure for hair loss. There is skepticism about its ability to regrow "deadzones," and concerns about its impact on those with hair transplants.

      community Is PP405 really that good or another "scam"?

       3 upvotes 7 months ago
      PP405 is considered a potential alternative to minoxidil and finasteride, but its effectiveness and safety are still uncertain. Many users suggest sticking with proven treatments like finasteride and minoxidil due to the lack of long-term data on PP405.

      community What is next for pp405 in phase 2b?

       16 upvotes 1 year ago
      PP405 is progressing to Phase 2b trials, with results expected in late 2025 or early 2026, and potential Phase 3 trials in 2026. Some users experienced side effects from finasteride and are hopeful for PP405 as an alternative treatment.

      community Almost 11-Months of 1.25mg Fin EOD | 23M

       53 upvotes 11 months ago
      A 23-year-old male shared his 11-month progress using 1.25mg finasteride every other day and Nizoral/Dermazole, reporting reduced hair fall and new hair growth without major shedding. Users discussed the risks of finasteride for younger individuals and suggested consulting a doctor, with some recommending minoxidil as an alternative.

      community So is this the actual trial results for pp405?????

       94 upvotes 5 months ago
      PP405 shows promising results for hair growth, potentially outperforming finasteride without side effects like erectile dysfunction. Users discuss using treatments like minoxidil, pyrilutamide, nizoral, and alfatradiol while waiting for PP405's availability.

      community 5 month update, minoxidil and finasteride

       724 upvotes 1 year ago
      The user is happy with hair regrowth after 5 months using topical minoxidil twice daily, oral finasteride once daily, derma stamping weekly, and Watermans shampoo. They noticed darker hair and stopped using creatine, suspecting it worsened hair loss.

      community Jxl069 (pp405 api) week 8 update

       205 upvotes 1 year ago
      The user shared minimal results from using JXL-069 for hair loss, noting a slight lengthening of vellus hairs and plans to switch to a prodrug variant due to limited effectiveness. They also mentioned using finasteride and minoxidil, which have plateaued in results.

      community Scalp Microneedling with Stemcell and Exohealer

       149 upvotes 3 months ago
      A user tried scalp microneedling with stem cells and exohealer in Korea for hair loss, costing $2.5k, and is awaiting results. Another user shared their experience using various growth factors and supplements, noting it improves existing hair but doesn't grow new hair, requiring monthly maintenance.

      community HMI-115 update: Chime Biologics and Hope Medicine Enter Manufacturing Agreement to Speed up the Launch of First-in-class Antibody Drug HMI-115 Targeting Endometriosis and Androgenic Alopecia

       110 upvotes 2 years ago
      Chime Biologics and Hope Medicine are speeding up the launch of a first-in-class antibody drug, HMI-115, for endometriosis and androgenic alopecia. The treatment involves a series of subcutaneous injections, has shown promising results in phase 1, and continues to promote hair regrowth even after the treatment is stopped.