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GlossarySkin Structure (Dermal Structure)

complex organization of skin's layers and components

Skin structure, also known as skin anatomy or dermal structure, refers to the complex organization of the skin, which is the body's largest organ. It consists of three primary layers: the epidermis (the outermost layer providing a barrier and creating skin tone), the dermis (beneath the epidermis, containing tough connective tissue, hair follicles, and sweat glands), and the hypodermis (deeper subcutaneous tissue made of fat and connective tissue). These layers work together to protect the body, regulate temperature, and provide sensory information.

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community GT20029 Anageninc Market Availability

Busy_Trick_6366 in Research/Science 164 upvotes 1 year ago

The conversation discusses the potential market release of a hair loss treatment called GT20029 by Anageninc, with users expressing interest and discussing the importance of safety and effectiveness. Some users plan to contact Anageninc to show demand for the product.

community PP405: The Ultimate Hair Loss Drug for Complete Hair Growth

noeyys in Research/Science 206 upvotes 1 month ago

PP405 is a new hair loss treatment in phase 2 trials that may promote hair growth by increasing lactate production and activating hair follicle stem cells. It could potentially replace hormone-disrupting treatments like Minoxidil and finasteride.

community Is it possible for androgenic alopecia to begin at early adolescent years?

Uncle__Sheogorath in Chat 70 upvotes 1 year ago

Hair loss can begin in early adolescence and cause mental anguish. Treatments mentioned include eating cruciferous vegetables, engaging in physical activity, and maintaining scalp hygiene.

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

nkrata in Research 830 upvotes 6 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Kintor has released an investor relations memo regarding Chinese Phase III trials for Pyrilutamide

poiuytrewq_poiuytrew in Update 50 upvotes 1 year ago

Kintor's Pyrilutamide (KX-826) showed hair growth in Chinese Phase III trials but did not significantly outperform placebo. The treatment was safe with no major adverse reactions reported.

community Comprehensive Microneedling Guide

throwoveraccount in Microneedling 294 upvotes 2 years ago

Microneedling for hair restoration involves daily use of a 0.3 mm device and weekly use of a 0.5 mm device. Combining microneedling with Minoxidil can enhance hair growth.

community The truth about Dutasteride (w/ sources)

degenwealth in Finasteride/Dutasteride 52 upvotes 2 years ago

The effectiveness of Dutasteride compared to Finasteride in treating hair loss, with evidence given such as studies and experiences, as well as discussion around whether one should switch from Finasteride to Dutasteride. There is also a discussion on post-Dutasteride syndrome.

community Oral minoxidil is not good for your health, let’s use research chemicals bought from AliExpress

BiluPax in Satire 551 upvotes 2 years ago

. This conversation discussed the efficacy of Minoxidil and Finasteride as treatments for hair loss, with a focus on the potential side effects of taking Oral Minoxidil. Some users shared their experiences with both treatments and there was debate over whether they were safe or not.

community Regrowing my hair/line without Min or Fin September (update) mechanical stimulation

MyThinningConfidence in Finasteride 24 upvotes 6 years ago

The user regrew their hairline using mechanical stimulation, including a 1.5mm derma roller weekly, daily scalp massages, and other treatments like Nizoral, zinc pyrithione, fish oil, and Lipogaine The Big 5. They did not use Minoxidil or finasteride.

community Eirion Therapeutics Announces Potential Breakthrough Treatment for Hair Loss Based on First-in-Man Clinical Trial Results

No_Hunt8773 in Update 415 upvotes 1 month ago

ET-02, a new hair loss treatment, shows promising results with a 6-fold increase in hair count, potentially outperforming minoxidil by activating stem cells in hair follicles. Further trials are ongoing to confirm its efficacy and safety, with potential market release in the future.

Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

MagicBold in Research 823 upvotes 3 months ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

community Hair repigmentation of poliosis circumscripta in androgenetic alopecia patient treated with exosomes and fractional picosecond laser

Terrible-Passage8868 in Product 2 upvotes 11 months ago

Exosomes combined with fractional picosecond laser treatment were effective in treating androgenetic alopecia and promoting repigmentation in white hair patches. The role of exosomes in hair repigmentation, particularly in conditions like poliosis, is not well-studied.

community Clearing the air on how non-surgical treatments really work

ImgurIsPrettyBad 15 upvotes 5 years ago

Treatments for hair loss, including finasteride, dutasteride, minoxidil, ketoconazole, microneedling, and low level laser light therapy, which aim to reduce DHT production, increase cell absorption and blood flow, and stimulate epidermal stem cells. It also stresses the importance of patience when using these treatments.

community Finally Managed to Download Somebody's Alex pdf so try to share it

Sorry_Alex_ThrowAway in Research/Science 70 upvotes 11 months ago

The conversation discusses a shared PDF about hair loss treatments, which might help those not seeing results with Minoxidil, Finasteride, and RU58841. Some users are skeptical about the content's value and the price charged for it.

community Scalp slapping to increase blood flow?

IcyOpinion3893 in Treatment 22 upvotes 8 months ago

This post and conversation are about using scalp slapping to increase blood flow for hair growth. One user suggests using minoxidil instead.

community Anyone using CB-03-01? What are you thoughts? How do you get it from powder to solution? What strength should be used?

alibabasfortythieves in Treatment 6 upvotes 5 years ago

The conversation is about someone considering using CB-03-01 for hair loss but has ordered finasteride, which they are hesitant to use. They are seeking advice on how to prepare CB-03-01 from powder form and the appropriate strength to use.

community Topical finasteride has affected my hormones

Weak-Protection8580 in Finasteride/Dutasteride 27 upvotes 1 year ago

A 21-year-old experienced hormone changes after using self-made topical finasteride for hair loss, including a 20% decrease in DHT, a 47% increase in testosterone, and a 39% increase in estradiol. The user previously used minoxidil and microneedling but is now seeking ways to balance hormones, possibly through supplements or dosage adjustments.

community A Scientific Perspective in Microneedling for Alopecia

RhadTrad in Microneedling 43 upvotes 5 years ago

The post and conversation are about microneedling as a treatment for alopecia. It provides a comprehensive review of scientific literature on the technique and its application.

community How all hormones affect our hair follicles. Not just DHT. Take a look at this paper. Prolactin, melatonin, cortisol, progesterone, testosterone and more

Combfromhell in Research/Science 126 upvotes 2 years ago

The conversation discusses various factors affecting hair loss, not just DHT, and mentions treatments like Minoxidil, finasteride, and melatonin. Some users report personal experiences with these treatments and hormone tests, while others speculate on the role of hormones like prolactin and cortisol in hair loss.

community Topical Finasteride Doesn't Directly Reduce 5ar Enzyme on Scalp

Zeweny in Finasteride/Dutasteride 72 upvotes 1 year ago

Topical Finasteride doesn't directly reduce 5ar enzyme on scalp and has the same mechanism as oral, needing to go through the liver. Users debate the accuracy of this information and discuss various studies and experiences.

community Topical Dutasteride. Does it work?

excursionxbox in Finasteride/Dutasteride 13 upvotes 8 months ago

Topical dutasteride may be effective for hair loss by staying in the scalp and minimizing bloodstream absorption, potentially improving hair results and reducing side effects. The user seeks advice on its effectiveness.

community Fin/min/microneedling ~9 months – no results, actually worse

harlital in Progress Pictures 96 upvotes 1 year ago

User harlital shared their 9-month hair loss journey using finasteride, minoxidil, and microneedling but experienced worse results. Commenters suggested patience, checking for other causes, and considering dutasteride after 12-24 months if no improvement.

community The Real Cause Of Androgenetic Alopecia

AccutaneEffectsInfo in Research/Science 673 upvotes 3 months ago

Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hair growth.

community New and Interesting HairLoss Studies/Papers/Reviews

TerpsandCaicos in Treatment 41 upvotes 5 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

community Hope for older men! 57 year old male 6 mo. progress pics. Minoxidil, RU58841, Microneedling, Nizoral

Icy_Comfort8161 in Progress Pictures 27 upvotes 2 years ago

A 57-year-old man shared his 6-month hair regrowth progress using RU58841, Minoxidil, microneedling, and Nizoral. He experienced significant improvement, with a smaller bald spot, thicker hair, and hairline regrowth.

community New study shows .5mm microneedle to be most effective?

kennyfunkhouser69 in Microneedling 35 upvotes 6 months ago

A user shared a video suggesting that 0.5mm microneedles are most effective for hair growth. Other users mentioned different microneedle lengths and advised consulting a dermatologist for personalized treatment.

community 4 months M26 Fin/Min/Keto/microneedle

Regular-Pride3444 in Progress Pictures 39 upvotes 1 year ago

A 26-year-old male shared progress pictures after 4 months of treating hair loss with finasteride (1.25 mg on Mondays, Wednesdays, and Fridays), topical minoxidil twice daily, ketoconazole shampoo twice weekly, and weekly microneedling at 1.5 mm. He is seeing hair growth improvement, especially in the front, and is considering hair grafts for the crown area if necessary for more density.

community M32, almost 3 moths, fin oral 1,25g/daily + min 2xday + keto 2% shapoo 1/week microneedling once a week

Bartdegrand in Progress Pictures 31 upvotes 1 year ago

A 32-year-old man has been treating his hair loss with daily oral finasteride (1.25g), twice-daily topical minoxidil, weekly ketoconazole 2% shampoo, and weekly microneedling for almost three months, with no side effects from finasteride. He started with a Hamilton Norwood scale rating of 5 and has seen improvement without experiencing pain by using a 0.8mm needle length for microneedling.

community 9months progress fin/derma pen/minoxidil

olli3330 in Progress Pictures 997 upvotes 4 years ago

A user's 9 month progress using Finasteride, Derma Pen/Roller and Minoxidil to treat hair loss. Replies in the conversation include advice on topical application of Minoxidil and Dutasteride for regrowth and hair thickness.

community Sharing my 3.5 year journey, keep grinding guys

Dc__stoner in Progress Pictures 228 upvotes 9 months ago

The user shared a 3.5-year hair loss treatment journey using 1 mg finasteride daily and minoxidil foam, noting significant improvement, especially in the third year. They also mentioned using Nizoral shampoo twice a week and supplements like vitamin D3, biotin, and omega 3 and 6.