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      community Possible explaination for Finasteride Reflex Hyperandrogenicity

       6 upvotes 4 years ago
      The user has been using finasteride and minoxidil for hair loss but experienced worsening temple recession. They suspect they might be more sensitive to testosterone and are considering trying RU58841 or CB 03 01 as additional treatments.

      community Chinese Research Chemicals You Suggest

      in Research/Science  3 upvotes 1 year ago
      The conversation discusses hair loss treatments, specifically RU58841, with mentions of side effects from finasteride and dutasteride. Alternatives like Pyri, KX-826, and Breezula are also mentioned.

      community I want to add a topical anti androgen to my routine

       4 upvotes 2 years ago
      RU58841 is considered an effective topical anti-androgen for hair loss, often used with minoxidil. Concerns exist about its purity and sourcing since it's not FDA-approved.

      community 2.5 mg/ED dut and 1% pyrilutamide, still getting itch?

       1 upvotes 1 year ago
      The user switched from finasteride to 2.5 mg dutasteride daily and added 1% pyrilutamide to address persistent scalp itch, but the itch remains. They also use 2% ketoconazole and 2.5% selenium sulfide shampoo for temporary relief.

      community DHEA, the culprit behind DUPA ? Read this!

       20 upvotes 3 years ago
      High DHEA levels may contribute to hair loss by increasing DHT in hair follicles, potentially explaining why finasteride is ineffective for some. Treatments like high-dose dutasteride and RU58841 are suggested, but the underlying cause, such as adrenal issues, should be investigated.

      community When should we get the next news about PP405

       24 upvotes 10 months ago
      Results for PP405 are expected next year, with concerns about its pricing and potential black market availability. Some users believe it may be slightly more effective than finasteride and dutasteride, and combining it with treatments like minoxidil and microneedling could be beneficial.

      community Long term RU 58841 users what’s going on with yall?

       6 upvotes 9 months ago
      Users discuss using RU58841 with finasteride, dutasteride, and minoxidil for hair loss, noting reduced itching and effective results. Some users report no side effects, while others experience side effects with dutasteride.

      community Purchasing and Shipping Alpecin DMG to the United States.

       3 upvotes 11 months ago
      A user is seeking help to purchase and ship Alpecin DMG to the United States due to issues with eBay sellers. They prefer Alpecin DMG over minoxidil because of concerns about minoxidil's effects on insulin production, as they have diabetes.

      community Clascoterone full results 2026

       7 upvotes 2 weeks ago
      Clascoterone results are anticipated to be released in fall 2026, possibly at the EADV conference. Users express skepticism and humor about the release date.

      community Dut only? Had to drop oral minoxidil

      in Treatment  2 upvotes 1 year ago
      The user stopped oral minoxidil due to side effects and is now using dutasteride mesotherapy and plans to start oral dutasteride. They are concerned about potential hair shedding and wonder if dutasteride alone will be effective.

      community Breezula phase 3 results said to be released next month

       26 upvotes 1 year ago
      Breezula's phase 3 results are expected soon, with discussions on the effectiveness of androgen receptor antagonists like spironolactone and the potential of GT20029. Users express skepticism about new treatments and discuss the complexities of male pattern baldness, often relying on finasteride despite its side effects.

      community who in here has used ru58841 , and how did it go

       11 upvotes 8 months ago
      RU58841 had mixed results for hair regrowth, with some users experiencing no change and others noting regrowth but also side effects like libido issues and chest pain. Some users combined it with other treatments like finasteride and dutasteride, with varying effectiveness.

      community Pyrilutamide - Worth it if can’t use Fin?

      in Research/Science  4 upvotes 1 year ago
      Pyrilutamide is being discussed as an alternative for those who can't use finasteride, but users report it may be ineffective at low concentrations. Some users are combining it with minoxidil, microneedling, and other treatments, but results vary.

      community PP405 2a study was a safety study. Some rational explaining.

       22 upvotes 1 year ago
      The conversation discusses the safety study of PP405, emphasizing that early trials focus on safety rather than efficacy, and that any efficacy data from such a short study should be viewed skeptically. It also highlights that the information released is primarily for securing funding, and that meaningful efficacy results are expected in later phases.

      community Pyrilutamide/KX-826 for women?

      in Treatment  1 upvotes 1 year ago
      Pyrilutamide/KX-826 is being considered as a potential treatment for female androgenetic alopecia (AGA), but its high cost and limited data on effectiveness are concerns. Kintor markets it for both men and women.

      community Topical - Lantoprost .01%, MIN 10% DUT .05%, Hydrocortisone 1% Progrestron .025%

      in Treatment  6 upvotes 1 year ago
      A user was prescribed a topical treatment for hair loss including Latanoprost, Minoxidil, Dutasteride, Hydrocortisone, and Progesterone, after using an oral Minoxidil and Finasteride combo without significant results. Concerns were raised about the long-term use of hydrocortisone, with suggestions to consult a doctor regularly.

      community PP405 (Everychem 3HP) Users - Assemble and share your story!

      in Chat  19 upvotes 4 months ago
      Users discussed the effectiveness of Everychem's solution, similar to PP405, with some reporting improved hair thickness and new growth. Concerns were raised about safety and the legitimacy of the product, with some users advising against purchasing research chemicals.

      community Side effects of topical azelaic acid?

       4 upvotes 5 years ago
      Azelaic acid is considered a strong DHT inhibitor with no reported sexual side effects, making it a potential alternative for those who cannot use finasteride. It can be used with minoxidil, but may cause skin irritation.

      community High estradiol from finasteride

       3 upvotes 4 years ago
      The user experienced high estradiol levels and side effects after stopping finasteride and is concerned about whether these hormonal imbalances are temporary. They are seeking advice on reversing the condition without starting new treatments due to hypersensitivity to finasteride.

      community Exalted Dutasteride master race

       4 upvotes 1 month ago
      Dutasteride is seen as a more effective treatment for hair loss compared to finasteride and minoxidil, with users noticing reduced hair fall and thicker hair within weeks. Many users report taking 0.5 mg of Dutasteride daily, sometimes alongside finasteride, and suggest transitioning gradually to avoid shedding.

      community Alternatives if can't tolerate minoxidil?

       4 upvotes 3 weeks ago
      The user is experiencing side effects from oral minoxidil and is considering switching to a topical solution or reducing the dose. They are also using dutasteride and are seeking advice on managing side effects and treatment alternatives.

      community Anyone tried topical adenosine?

       5 upvotes 3 years ago
      Hair loss discussion includes treatments like Minoxidil, Finasteride, and RU58841. User asks for opinions on topical adenosine as a treatment.

      community Does anyone has experience with Redenysl?

      in Product  4 upvotes 4 years ago
      Redenysl is marketed as a hair growth solution but is considered ineffective by users, with some suggesting it is a scam. Alternatives like minoxidil, finasteride, and dutasteride are recommended, with hair transplants being the most effective option.

      community Mechanism of Action these drugs re-grow hair?

       2 upvotes 2 years ago
      Minoxidil, finasteride, and RU58841 promote hair growth by different mechanisms, with minoxidil and prostaglandin E1 being specifically mentioned. Corticosteroids can also cause hair growth.

      community What's your thoughts on Pyrilutamide

       6 upvotes 9 months ago
      The conversation is about using pyrilutamide and RU58841 as topical solutions to prevent hair loss. Pyrilutamide is considered safer but less potent than RU58841, which some users find effective despite potential side effects like heart palpitations.

      community Diy dutesteride please help MCT oil or PG?

       1 upvotes 9 months ago
      A user is making their own dutasteride solution using MCT oil but is concerned about its effectiveness and bioavailability. They are considering using propylene glycol or adding ethanol for better results, while others suggest the current dosage might be excessive.

      community Pyrilutamide / KX-826 | Discussion EU

       4 upvotes 3 years ago
      The conversation is about a user expressing concerns over the safety of a new drug called Pyrilutamide (also known as KX-826) for hair loss. The user will only trust the drug if it's permitted by EU regulations and sold by a reputable company.