Pyrilutamide Phase 3 approved, starting early 2022 with 416 subjects for 24 weeks. Drug potentially better than RU and Breezula, with some users reporting no side effects.
RU58841, an anti-androgenic compound, showed early promise for treating alopecia but faced challenges after its patent in 1997. Despite advancing to Phase II trials, safety concerns and financial struggles led Aventis to abandon its development. Proskelia, which later merged into ProStrakan, couldn't prioritize the drug, leading to its eventual stagnation and failure to reach the market.
A user shared progress pictures after 9 months of using 1 mg finasteride, 2.5 mg oral minoxidil, microneedling, and ketoconazole, noting no visible improvement and considering switching fully to dutasteride. Another user commented that there were gains in the temples and praised the early intervention.
The user is sharing their experience with using 0.5mg dutasteride, 2.5mg oral minoxidil, and hair dye for 45 days. Another user encourages them to continue as it is still too early to see significant improvement.
The user is seeking recommendations for topical saw palmetto and pumpkin seed oil products to treat early male pattern baldness and is considering different options available online. They are specifically asking which saw palmetto product to choose between two provided links.
The user experienced minor hair regrowth after 4 weeks of using oral minoxidil and dutasteride, despite initial side effects like minor sickness and reduced sexual desire. The user is surprised by the early results and plans to continue the treatment, also using Nizoral shampoo.
Some men have strong balding genetics that treatments like Dutasteride, Minoxidil, or Finasteride may not fully address. Early intervention is believed to help, but many accept hair loss without treatment.
The conversation is about a user's positive progress with hair regrowth using oral dutasteride and topical Minoxidil 5% over seven months. The user reports no side effects and started experiencing significant hair loss in their early 20s.
The user shared a one-year update on using oral finasteride (1.1 mg) and oral minoxidil (3 mg) along with ketoconazole shampoo, reporting significant hair regrowth and satisfaction with the results despite some side effects like thicker eyebrows and chest hair. The user encourages others to start treatment early and plans to continue the current regimen for further improvement.
Hair follicles can be dormant and potentially revived with treatments like finasteride and minoxidil, but irreversible loss occurs if certain structures are destroyed. Early intervention is more effective, and additional methods like microneedling may help.
The user switched from finasteride to dutasteride after experiencing significant hair shedding, and is also using oral minoxidil. Dutasteride helped stop the shedding, but it's too early to determine if it will reverse hair loss.
Hair transplants can initially yield good results, but native hair is more reliable, and transplanted hair may still be lost over time. Early intervention with treatments like topical finasteride and minoxidil is recommended, but it's important to start with lower doses and manage expectations realistically.
Genetic factors, enzyme activity, and DHT sensitivity affect individual responses to hair loss treatments like finasteride, minoxidil, and dutasteride. Starting treatments early can slow hair loss, but results vary among individuals.
Finasteride and Minoxidil can maintain hair and slow hair loss for many years, but individual results vary, and some may eventually need a hair transplant. Starting treatment early increases the chances of maintaining hair without needing a transplant.
The user has been using oral minoxidil, finasteride, and dutasteride to prevent hair loss, despite not showing significant balding. Many commenters believe the treatment is excessive, while some support early prevention.
CRISPR shows promise for treating hair loss by targeting specific genes. Current treatments include Minoxidil and finasteride, but CRISPR could offer a more precise solution, though it is still expensive and in early stages.
A user shared their 2.5-year hair loss treatment success using 1mg finasteride daily and switching from 5mg to 2.5mg minoxidil. They reported no significant side effects and emphasized the importance of early treatment.
The conversation is about the effectiveness of hair loss treatments like finasteride, dutasteride, and minoxidil. Users agree these treatments help maintain hair but don't guarantee miraculous regrowth, emphasizing early intervention for best results.
A user ordered pyrilutamide (KX826) to stop hair loss and is seeking success stories. Replies indicate that it's too early to evaluate the product's effectiveness, as it takes several months to see results.
Users discussed hair loss treatments, specifically minoxidil and finasteride. They shared personal experiences and advice on starting these treatments early.
A user shared their 3-month progress using a combined finasteride and minoxidil pill for hair loss, noting early signs of regrowth. They also use biotin shampoo/conditioner, take Vyvanse and Propranolol, and bleach/dye their hair every 3 weeks.
Finasteride can continue to improve hair loss for up to 10 years, with the best results seen when started early. Combining treatments like minoxidil, dermarolling, or RU58841 may enhance effectiveness.
The user started with 1mg oral finasteride and 2.5mg oral minoxidil daily in January 2023, but stopped minoxidil due to an elevated heart rate. They then saw regrowth after beginning topical minoxidil and microneedling in early 2024.
People discussing hair loss treatments emphasize the need for patience, as results from using finasteride and minoxidil can take 8-12 months or longer. Some users report early signs of improvement, while others experience continued shedding or slower progress.
GriffinLiftin experienced significant hair regrowth after 6 months using oral finasteride and minoxidil, along with hair care products like leave-in conditioner, curl-cream, and olive oil. They started treatment early due to a family history of balding and are pleased with the life-changing results.
The conversation discusses whether age affects the side effects and effectiveness of hair loss treatments like finasteride and dutasteride. Some believe early treatment yields better results, while others mention varied outcomes across ages and personal regrowth experiences without a clear consensus on age impact.
A user successfully improved their hairline after 15 months using topical minoxidil and dutasteride. Some commenters question the necessity of treatment given the user's original hair condition, while others support early intervention.