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      community Looking for a second opinion about my Dutasteride plan at 19+extra questions

       1 upvotes 8 months ago
      A 19-year-old plans to start Dutasteride 0.5mg three times a week to combat genetic alopecia and preserve hair density, with concerns about potential shedding before prom. Users suggest starting the treatment after prom to avoid shedding, and provide advice on where to purchase the medication.

      community AttentionHomemade Topical Fin Users- requesting Feedback

       5 upvotes 2 years ago
      A user is seeking feedback on a homemade topical finasteride formula for hair loss, consisting of 7.5 mg of finasteride, propylene glycol, ethanol, and distilled water. They aim to achieve a 0.0125% solution by applying 2 ml daily.

      community Hydrophobic Finasteride. Why don’t we have it?

       6 upvotes 1 year ago
      The conversation discusses the potential benefits of creating a hydrophobic version of finasteride to reduce systemic side effects while maintaining scalp health. It compares this idea to fluridil, which is designed to be hydrophobic and has less systemic absorption.

      community Any chemists want to manufacture PP405 / JXL069? (Steps inside)

       114 upvotes 1 year ago
      The conversation discusses the potential of PP405 as a hair loss treatment, with some users expressing skepticism and others hopeful about its development. There is also mention of other treatments like Minoxidil, Finasteride, and Pyrilutamide, with users debating the effectiveness and safety of self-experimentation versus waiting for clinical trial results.

      community If PP405 works it will be fkn impossible to buy it.

       103 upvotes 10 months ago
      PP405 is a potential hair loss treatment that may activate dormant hair follicles, but there are concerns about its effectiveness, cost, and side effects. Users discuss treatments like minoxidil, finasteride, and RU58841, expressing skepticism about PP405's long-term success and accessibility.

      community Sooo whats the consensus about pp405 now?

      in Chat  75 upvotes 5 months ago
      PP405 may help with hair regrowth, especially when combined with minoxidil and finasteride, but its long-term effectiveness is unclear. Phase 3 trials are expected to begin soon, with results in a few years.

      community Today, The DHT Attacked

       41 upvotes 8 years ago
      The conversation humorously discusses the effects of DHT on hair loss, with references to treatments like finasteride and RU58841. Users share exaggerated stories about DHT's impact, highlighting its negative reputation.

      community Dutasterid per Fragebogen in Deutschland?

      in Finasteride/Dutasteride  5 upvotes 1 month ago
      The conversation discusses the high cost and process of obtaining Dutasteride in Germany, with users sharing alternatives and experiences. OP uses Dutasteride for prostate health and beard growth reduction, not for hair loss.

      community Thinking about using PP405 and RU58841

       1 upvotes 8 months ago
      The conversation is about a person using dutasteride and minoxidil for hair loss, considering adding RU58841 and PP405 for more density. They are seeking advice on using these treatments and exploring other options like GT20029.

      community Pelage Pharmaceuticals Phase 3 Trials for PP405 Start in September 2026

       171 upvotes 3 days ago
      Pelage Pharmaceuticals is starting Phase 3 trials for PP405 in September 2026, with potential market release by 2030. Users discuss various hair loss treatments like minoxidil, finasteride, RU58841, kx, breezula, and gt20029, expressing hope for future hair restoration.

      community Post TCA pic and two month in, just posting baseline and an update.

       6 upvotes 7 months ago
      The conversation is about a user's hair loss treatment regimen, which includes Dutasteride, oral Minoxidil, topical Dutasteride, Minoxidil sulfate, antioxidants, and various supplements. The user is also using a derma stamp and has paused Tretinoin due to a TCA peel recovery.

      community DHT before and after from .5mg DUT once a week

      in Research/Science  29 upvotes 10 months ago
      The user experienced improved libido and erections after reducing DHT levels with 0.5mg of dutasteride once a week, despite previous side effects from finasteride. They are also on testosterone replacement therapy and have not noticed major personality changes.

      community PP405 - A True Breakthrough or Another Disappointment?

       34 upvotes 1 year ago
      PP405 shows potential for hair growth, with 31% of advanced balding men experiencing over 20% increase in hair density in 8 weeks. However, skepticism persists due to selective data presentation and lack of long-term results, with comparisons to treatments like minoxidil and finasteride.

      community GHK-Cu 2 month transformation!

      in Progress Pictures  6 upvotes 3 weeks ago
      GHK-Cu significantly improved hairline with baby hairs in 2 months, despite previous lack of results from oral dutasteride and minoxidil. OP suggests trying GHK-Cu due to noticeable hair regrowth.

      community ”Why are we not funding this?” - Peter Griffin

       221 upvotes 1 year ago
      Topical finasteride can reduce scalp DHT as effectively as oral finasteride with fewer systemic effects, but availability is limited. Some users make their own solutions due to limited access.

      community When should we get the next news about PP405

       24 upvotes 10 months ago
      Results for PP405 are expected next year, with concerns about its pricing and potential black market availability. Some users believe it may be slightly more effective than finasteride and dutasteride, and combining it with treatments like minoxidil and microneedling could be beneficial.

      community how to make dut pills from dut powder

      7 months ago
      A user discusses making DIY dutasteride capsules from powder bought from China, using a mix of MCT oil and propylene glycol. Others warn about the risks of incorrect dosing, potential degradation, and the possibility of receiving fake products.

      community Pelage PP405 Phase 2a completed.

       61 upvotes 7 months ago
      Minoxidil, finasteride, and RU58841 are discussed as treatments for hair loss, with excitement around a new drug, PP405, and a reformulated oral minoxidil in trials. Concerns about cost, side effects, and long-term use are also mentioned.

      community Passive/preventative anti-DHT haircare routine?

      in Treatment  2 upvotes 1 year ago
      The conversation discusses preventative hair care measures for hair loss, focusing on non-prescription treatments like rosemary, peppermint, castor oils, microneedling, and ketoconazole shampoo. It also touches on the use of finasteride, minoxidil, and RU58841 for those experiencing hair loss.

      community Can we all agree that PP405 is now 4 years away

       94 upvotes 1 year ago
      PP405 is expected to be available in 2028, with ongoing discussions about its timeline and potential effectiveness. Current treatments mentioned include sublingual Minoxidil and Vederamicd, with some users experiencing side effects from oral Minoxidil.

      community How can my DHT be so low without Finasteride on cycle?

      3 months ago
      A user is curious why their DHT levels are not higher despite using 400mg of testosterone without finasteride, and wonders if zinc or GHK-Cu injections could be influencing this. Another user suggests that more testosterone typically leads to more DHT, but the user might be fortunate not to exceed normal DHT levels.

      community 6 months of finasteride and ghk-cu

      in Progress Pictures  18 upvotes 5 months ago
      The conversation is about hair loss treatment progress using finasteride and GHK-CU over six months. Users discuss application methods and share experiences with GHK-CU and AHK.

      community 2.5mg Dut users - Assembly and share your story!

      in Chat  11 upvotes 5 months ago
      Dutasteride is considered more effective than finasteride for hair loss, with some users increasing the dose to 2.5mg daily for better results. Experiences vary, with some seeing regrowth and others not, and side effects are a concern.

      community Progress at ~6 month mark dut/min

       13 upvotes 6 months ago
      A user shared their 6-month progress using daily oral dutasteride and minoxidil, along with monthly mesotherapy including zinc, dutasteride, minoxidil, biotin, and panthenol, reporting no noticeable side effects. Encouragement was given to continue despite potential hair shedding.