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    GlossaryDiscoid Lupus Erythematosus

    chronic autoimmune condition causing red, scaly skin patches

    Discoid Lupus Erythematosus (DLE) is a chronic autoimmune condition that primarily affects the skin, leading to the development of red, inflamed, and scaly patches, often on the face, scalp, and ears. These lesions can cause scarring and permanent hair loss if they occur on the scalp.

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      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 1 month ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community HMI 115 Phase 2 - Leaked pics from Discord

      in Research/Science  360 upvotes 4 months ago
      The conversation discusses HMI 115, a new hair loss treatment with promising results, showing a significant increase in hair density after two months. Some users are skeptical, while others are hopeful for its release and potential affordability.

      community We need to create a Discord KX-826 Monotheray group:

      in Research/Science  30 upvotes 2 years ago
      The conversation is about starting a Discord group for people using KX-826 as their only treatment for hair loss, excluding those who are not serious or use multiple treatments. Someone agrees with the idea but mentions "GP :3," which is unclear.

      community Discussion: Keratin Microsphere Results

      in Treatment  30 upvotes 6 months ago
      Keratin microspheres may offer additional mechanisms to combat hair loss compared to minoxidil. The process to create these microspheres is relatively simple and can be done at home with basic equipment.

      community Group Buy for MR antagonist finerenone

      in Product  11 upvotes 1 year ago
      User discusses group buy for finerenone, a third-gen mineralocorticoid antagonist for hair loss treatment. Finerenone inhibits TGFb, NOX, and ROS, and improves renal and cardiac function; topical dose should be no more than 10mg per day.

      community Dutasteride RAISES LIBIDO!

      in Treatments  222 upvotes 3 months ago
      Dutasteride can significantly increase libido, more so than finasteride. Users reported higher libido when switching from finasteride to dutasteride.

      community My experience with 1mg fin eod

      in Finasteride/Dutasteride  21 upvotes 1 year ago
      A 30-year-old man shared his experience with finasteride, taking 1mg every other day, which led to sexual side effects and other issues, prompting him to stop the treatment despite initial hair improvement. He previously tried natural methods and minoxidil without much success and is now considering a buzzcut.

      community Twist1 Group Buy: Yes it’s that easy

      in Research/Science  39 upvotes 2 years ago
      A group buy for testing a compound targeting Twist1 protein as a potential hair loss treatment. Inhibiting Twist1, which keeps hair follicles in growth phase, may prevent hair loss with minimal side effects.

      community Pyrilutamide (KX-826) vs CB-03-01 which one do you think is better?

      in Product  8 upvotes 2 years ago
      The conversation is about comparing hair loss treatments Pyrilutamide (KX-826) and CB-03-01, discussing their cost, side effects, and effectiveness. The user questions whether to try CB-03-01, which is more expensive and potentially less effective, or switch to the cheaper and possibly better Pyrilutamide.

      community Where the fuck are the pyrilutamide GB guys?

      in Chat  24 upvotes 2 years ago
      The effects of Pyrilutamide, a hair loss treatment that is being tested for June/July; and reports from people who have experienced side effects similar to those of RU58841, suggesting they may have been sold an incorrect product from their supplier.

      community Is anyone using fluridil (eucapil)?

      in Treatment  9 upvotes 2 years ago
      Hair loss discussion includes using fluridil (eucapil), minoxidil, and finasteride. One person takes 1 vial of fluridil daily and 1mg of finasteride every other day for effective treatment with minimal side effects.

      community Kintor KX-826 Group Buy Feedback

      in Research/Science  28 upvotes 2 years ago
      The conversation is about a group of people trying KX-826 for hair loss, with no serious side effects reported after 25 days of use. Some participants are experiencing less scalp itch and shedding, but it's too early for definitive results.

      community how about progesterone cream?

      in Research/Science  20 upvotes 4 months ago
      Progesterone cream might help with hair loss by inhibiting DHT production and suppressing prolactin, which can increase DHT. Some dermatologists have used progesterone for hair loss treatment, and it has been effective, sometimes combined with minoxidil, finasteride, and hydrocortisone.

      community Grey Market GT20029 and Frequency of Application

      in Product  10 upvotes 4 months ago
      The conversation is about the potential release of GT20029 on the grey market and concerns about its safety and authenticity. One user advises waiting for the official release by Kintor.

      community 1 Year Mark. 1mg Oral Finasteride, 5% Topical Minoxidil 2mL

      in Progress Pictures  196 upvotes 5 months ago
      The user has seen significant hair regrowth after one year using 1mg oral finasteride and 5% topical minoxidil, considering a hair transplant if progress stalls. They experienced an initial shedding phase and temporary erectile dysfunction, but no other side effects.

      community Fluridil/topilutamide experince

      in Treatment  3 upvotes 6 months ago
      A user is trying fluridil/topilutamide for hair loss and experiencing side effects like pain in the testicles and genital discomfort. They previously had adverse effects with finasteride, dutasteride, and RU58841, and are considering other treatments like topical dutasteride and spironolactone for maintenance before a hair transplant.
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