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GlossaryDehydroepiandrosterone (DHEA)

hormone produced by adrenal glands, precursor to sex hormones

Dehydroepiandrosterone (DHEA) is a hormone produced by the adrenal glands, which are located above the kidneys. It serves as a precursor to male and female sex hormones, including testosterone and estrogen. DHEA levels naturally decline with age and are sometimes supplemented to address various health issues, such as adrenal insufficiency, depression, and certain autoimmune diseases.

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community Hair loss - Blood work (High DHEAS)

in Research/Science 9 upvotes 2 years ago

A user has been taking finasteride for 5 months with no improvement in diffuse hair loss and suspects high levels of prolactin, cortisol, progesterone, and DHEAS, as well as iron, might be contributing to the issue. They are also taking vitamin D to address a deficiency.

community here is why isotretinoin might cause hair loss and maybe why dupa happens.

in Research/Science 7 upvotes 1 year ago

Isotretinoin may cause hair loss by increasing DHT through a precursor androgen, DHEAS. Treatments like topical antiandrogens (RU58841, pyrilutamide) and drugs increasing PPAR-y expression (pioglitazone) might prevent this hair loss.

community How does hair loss and recovery work?

in Chat 12 upvotes 2 months ago

Hair loss varies due to genetic sensitivity to DHT and other factors. Treatments discussed include finasteride, minoxidil, RU58841, and microneedling.

community Finasteride doesn't work for me in 2 years and my bloodtest result just came in.

in Progress Pictures 88 upvotes 1 year ago

A user has been treating hair loss with finasteride for two years without success and is experiencing an itchy scalp with seborrhea. Despite low DHT levels, they are still losing hair, suggesting that DHT might not be the main cause of their hair loss, and they are considering other treatments or causes.

community Going to a cosmetic derm soon. What should I ask for?

in Female 3 upvotes 1 year ago

Female, 28, losing hair since 17, using 200mg Spiro. Tried Minoxidil and ketoconazole with limited success, considering oral minox and seeking alternative treatments from cosmetic dermatologist.

community Whats up with Prolactine these days?

in Research/Science 20 upvotes 1 year ago

The conversation discusses the potential role of prolactin in hair loss and mentions treatments like HMI115, mucuna pruriens, Zinc, and B6 P5P for lowering prolactin levels. It also touches on the use of natural compounds and the lack of studies due to funding issues.

community fin + oral/topical minox + folexin + nizoral/head & shoulders + vitamin d. it works

in Update 33 upvotes 3 years ago

Finasteride is key for hair regrowth, supported by oral/topical minoxidil, Folexin, Nizoral/Head & Shoulders, and vitamin D. No side effects experienced; early intervention and patience are crucial.

community Female Hair Loss, Is there anything else I should be doing?

11 upvotes 10 years ago

A 20-year old female experiencing hair loss, who has had normal blood tests and is currently using minoxidil as recommended by her doctor. She is asking if there are any other treatments she should consider.

community DUPA - 20 YO - Non responder to everything

in Finasteride/Dutasteride 13 upvotes 2 months ago

A 20-year-old user experienced worsening hair loss despite using various treatments including topical and oral minoxidil, finasteride, and dutasteride. Other users suggested additional treatments like JAK inhibitors, RU58841, and lifestyle changes, but the user remains skeptical and frustrated.

community Have been on treatment for close to two years, need to know if I should continue or take dut

in Progress Pictures 52 upvotes 2 months ago

A 22-year-old male has been using finasteride, topical minoxidil, and oral minoxidil for hair loss but sees minimal improvement and is considering adding dutasteride. Users suggest additional treatments like dermarolling, PRP, and consulting a dermatologist, or considering a hair transplant.

community Ultimate Hairloss Flowchart (for beginners)

in Treatment 247 upvotes 1 year ago

The conversation discusses a hair loss flowchart for beginners, with mixed opinions on its effectiveness. Treatments mentioned include minoxidil, finasteride, dutasteride, microneedling, and vitamins.

community Possible explanation of why Dutasteride seems to be worse for some people’s hair.

in Treatment 47 upvotes 1 year ago

The conclusion of the conversation is that some individuals may experience a condition called reactionary hypergonadism when taking dutasteride for hair loss. This condition can lead to an increase in testosterone levels, which may worsen hair loss instead of improving it.

community 22M Fin and min everyday for 10 months, looks like my right temple is still receding

in Finasteride/Dutasteride 67 upvotes 1 year ago

The user is seeking opinions on their hair loss, specifically the receding of their right temple. They are considering switching to Dutasteride but are unsure if it will help. Other users suggest that their hairline has improved with the use of Finasteride and Minoxidil. One user mentions using RU58841 to thicken their hairline.

community 21F AGA - 4 month hair growth progress (Minoxidil 5%, finasteride 1mg, theradome LLLT, viviscal vitamins, PRP twice)

in Progress Pictures 257 upvotes 2 years ago

A 21-year-old female shared her 4-month hair growth progress using Minoxidil 5%, finasteride 1mg, Theradome LLLT, Viviscal vitamins, and PRP treatments twice. Commenters praised her progress and discussed other treatments like microneedling, but she noted her dermatologist advised against it due to potential scalp damage.

community I’m already DOING EVERYTHING!!!

in Female 27 upvotes 3 years ago

A 26 year old female dealing with hair loss who is considering treatments such as Spiro, minoxidil and finasteride. Other potential solutions mentioned are PRP treatment, a wig, and bio-identical estrogen combined with bica.

community Female AGA - Low Cortisol/Low DHEA

in Female 6 upvotes 1 year ago

Female (37) experiencing hair loss for 5 years, tried max dose of spiro and oral + topical minox without success. Discovered low cortisol and low DHEA levels, seeking functional medicine practitioner for help.

community Blood test 3 days after finasteride. Is it ok?

in Finasteride/Dutasteride 3 upvotes 5 months ago

A user asked if taking a blood test 3 days after starting finasteride would affect the results for Estradiol, FSH, SHBG, Progesterone, and DHEA-S. The conversation is about the timing of blood tests after beginning finasteride treatment.

community My Experience and a Discourse on "DUPA"

in Treatment 9 upvotes 5 months ago

The user discusses their hair loss experience, exploring various hypotheses including thyroid levels, vitamin D, DHEA, nutritional deficiency, diabetes, seborrheic dermatitis, lack of nutrition to hair follicles, chronic inflammation, female pattern hair loss causes, cortisol, and prolactin levels. They are currently using finasteride, beta-sitosterol, and have tried topical dutasteride and microneedling therapy.

community AA and Hirsutism but T levels are normal

in Female 8 upvotes 3 years ago

27-year-old female experiences aggressive hair thinning and hirsutism despite normal testosterone levels. Spironolactone and 2% minoxidil were ineffective; high DHEA sulfate levels may be the cause.

community I think I’m on to something

23 upvotes 5 years ago

The user shared their personal experience with hair loss, hormone imbalances, and treatments including testosterone boosters, natural estrogen blockers, and DHEA. They suggest that low-dose finasteride and natural hormone therapy could reduce hair loss with fewer side effects.

community Zix + Topical Fin : Blood Test Before/After, AMA and suggestions

in Treatment 47 upvotes 4 years ago

A user's plan to use Zix and topical finasteride (5AR inhibitors) for hair loss, followed by blood testing before/after. The user has suggested creating a fund to cover part of the cost of their blood tests. Replies to their post discuss the effectiveness of the treatments.

community Am I safe to take finasteride with these blood results?

in Finasteride/Dutasteride 1 upvotes 2 months ago

A user is concerned about taking 1mg/day of finasteride due to potential gynecomastia, given their blood results. They seek advice on how their hormone levels might be affected by blocking DHT.

community Is it possible that dutasteride won’t make you depressedd if finasteride did?

in Chat 16 upvotes 7 months ago

The conversation discusses whether dutasteride might cause less depression than finasteride for hair loss treatment, with some users suggesting it could due to different mechanisms of action or molecular size, while others express skepticism or share personal experiences with these medications.

community Pre Finasteride Treatment, is testing for free DHT necessary?

in Finasteride/Dutasteride 5 upvotes 1 year ago

The conversation is about whether testing for free DHT is necessary before starting Finasteride for hair loss, despite having other hormone tests available. One person suggests that genetic response to DHT is more important than DHT levels and advises starting Finasteride without the free DHT test.

community This is lagunaboy and I have fully recovered from PFS

in Finasteride/Dutasteride 5 upvotes 2 years ago

The user recovered from Post-Finasteride Syndrome (PFS) using a specific hormone protocol after trying finasteride and dutasteride. They now help others with PFS by reviewing blood work and offering personalized advice.

community The Hormonal Profile of MPB/AGA

in Research/Science 9 upvotes 3 years ago

Men with early male pattern baldness (MPB) may have hormonal abnormalities similar to those in women with PCOS. Specific treatments mentioned include Minoxidil, Finasteride, and RU58841.

community Just swallowed my first 1mg pill of finasteride! Let the journey begin...

in Finasteride/Dutasteride 29 upvotes 4 years ago

A user started taking 1mg finasteride for hair loss and plans to follow a thrice-weekly dosing schedule recommended by two doctors. They previously used saw palmetto without issues and are hopeful finasteride won't cause sexual side effects.

community Is it too late to regrow my hair?

in Question 14 upvotes 5 years ago

A 29 year old female with hair loss issues that have been linked to PCOS; the user has started taking Spironolactone and iron supplements in hopes of regrowing their hair, but is wondering if it's too late.

community Lifestyle choices and your hair....

6 upvotes 5 years ago

A person noticed increased hair thinning after changing their workout routine from cycling to weightlifting, which also coincided with a rise in testosterone levels. They are considering stopping intense workouts, switching to yoga, cutting out caffeine, and re-evaluating after a few months to see if it improves their hair condition.

community Has anyone had experience with 1mg + of dut?

in Finasteride/Dutasteride 9 upvotes 5 months ago

A user is asking about increasing their dutasteride dosage from 0.5mg to up to 2.5mg and whether it improves hair loss treatment. They are seeking experiences from others who have tried higher doses.