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    GlossaryDehydroepiandrosterone Sulfate (DHEA-S)

    hormone precursor influencing sex hormones and hair growth

    Dehydroepiandrosterone Sulfate (DHEA-S) is a hormone produced primarily by the adrenal glands, and it serves as a precursor to male and female sex hormones, including testosterone and estrogen. It plays a role in the development of secondary sexual characteristics and can influence hair growth and skin health. Elevated or decreased levels of DHEA-S can be indicative of various health conditions, such as adrenal disorders or polycystic ovary syndrome (PCOS).

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      community Female AGA - Low Cortisol/Low DHEA

      in Female  7 upvotes 1 year ago
      Female (37) experiencing hair loss for 5 years, tried max dose of spiro and oral + topical minox without success. Discovered low cortisol and low DHEA levels, seeking functional medicine practitioner for help.

      community Blood test 3 days after finasteride. Is it ok?

      in Finasteride/Dutasteride  3 upvotes 6 months ago
      A user asked if taking a blood test 3 days after starting finasteride would affect the results for Estradiol, FSH, SHBG, Progesterone, and DHEA-S. The conversation is about the timing of blood tests after beginning finasteride treatment.

      community AA and Hirsutism but T levels are normal

      in Female  8 upvotes 3 years ago
      27-year-old female experiences aggressive hair thinning and hirsutism despite normal testosterone levels. Spironolactone and 2% minoxidil were ineffective; high DHEA sulfate levels may be the cause.

      community Not everyone should immediately go on Fin if they are starting to bald

      in Finasteride/Dutasteride  21 upvotes 11 months ago
      The conversation suggests that people should consult a dermatologist to understand their type of hair loss before starting treatments like finasteride or dutasteride, especially if they have autoimmune issues or low DHT. Some participants believe in starting treatment like finasteride immediately if hair loss is due to DHT, while others recommend ruling out other causes and considering minoxidil first, especially for younger individuals.

      community One+ year 1mg Fin, Ketoconazole, and 3.75 Oral Min. I have DUPA. Switched from Topical to Oral Min.

      in Progress Pictures  142 upvotes 2 years ago
      A user's experience with hair loss treatments such as finasteride, ketoconazole, and oral minoxidil that have not yielded any results; other users suggest shaving the head or getting a wig, while others offer additional advice such as seeing a dermatologist, checking thyroid levels, switching to dutasteride and adding needling, and trying stemoxydine.

      community C’est terrible - at my wits end

      in Female  449 upvotes 1 year ago
      A 29-year-old woman is experiencing gradual hair thinning since age 15, suspects Androgenic Alopecia, and has tried 5% minoxidil with little success. She has purchased various hair loss treatments including minoxidil, dutasteride, finasteride, and spironolactone, but is cautious about starting them due to potential interactions with her ADHD medication.

      community Dutasteride 1 year regression. Depressing. (With pictures for proof)

      in Progress Pictures  14 upvotes 1 year ago
      A user shared their experience of hair loss progression after one year on dutasteride, expressing disappointment with no improvement and considering other treatments like RU58841. Other users offered mixed responses, some seeing no change, others suggesting the hair loss might have been worse without treatment, and discussing the role of testosterone and DHT in hair loss.

      community Pre Finasteride Treatment, is testing for free DHT necessary?

      in Finasteride/Dutasteride  5 upvotes 1 year ago
      The conversation is about whether testing for free DHT is necessary before starting Finasteride for hair loss, despite having other hormone tests available. One person suggests that genetic response to DHT is more important than DHT levels and advises starting Finasteride without the free DHT test.

      community 1 Year progress on topical fin and min

      in Progress Pictures  735 upvotes 3 years ago
      User shares 1-year progress using topical finasteride and minoxidil for hair loss, with positive results. Some users discuss trying topical dutasteride and varying dosages, while others share their experiences and ask about specific products.

      community Is it too late to regrow my hair?

      in Question  14 upvotes 5 years ago
      A 29 year old female with hair loss issues that have been linked to PCOS; the user has started taking Spironolactone and iron supplements in hopes of regrowing their hair, but is wondering if it's too late.

      community Lifestyle choices and your hair....

       6 upvotes 5 years ago
      A person noticed increased hair thinning after changing their workout routine from cycling to weightlifting, which also coincided with a rise in testosterone levels. They are considering stopping intense workouts, switching to yoga, cutting out caffeine, and re-evaluating after a few months to see if it improves their hair condition.

      community Please take a vitamin & hormone test

      in Chat  256 upvotes 1 week ago
      Checking vitamin and hormone levels is important for addressing hair loss, as deficiencies in vitamin D, zinc, and iron can affect hair growth. Treatments like finasteride, minoxidil, and vitamin supplements are used, but addressing deficiencies is crucial for effectiveness.

      community Finally progress! - 4 month on 1.25mg FIN (daily) + MIN + Dermarolling

      in Progress Pictures  198 upvotes 11 months ago
      The conversation discusses a user's progress after 4 months of using 1.25mg finasteride daily, minoxidil, and dermarolling to treat hair thinning, particularly on the sides and crown. The user believes finasteride made the most difference, and they share tips on managing hair loss and tracking progress.

      community DHT levels after 4 weeks of Fina and 8 weeks of Fina + 4 weeks of Duta

      in Update  35 upvotes 5 years ago
      The user reported early stage diffuse hair thinning and increased DHT levels after 4 weeks on Finasteride and 8 weeks on Finasteride plus 4 weeks on Dutasteride, despite the medications being authentic and stored properly. They are considering increasing their Dutasteride dosage due to the lack of side effects and are unsure if the treatment is helping their hair.

      community 26M Baseline blood work done before Finasteride

      in Finasteride/Dutasteride  8 upvotes 3 years ago
      A person considering finasteride for hair loss checked their hormone levels before starting treatment. They are concerned about the potential increase in estradiol and its effects, as well as the impact on their sex hormone-binding globulin (SHBG) and free testosterone levels.

      community Follow up appointment with Donovan.

      in Finasteride/Dutasteride  17 upvotes 1 year ago
      The user was diagnosed with DUPA and initially treated with finasteride, then switched to dutasteride which worsened their hair loss. They are now returning to finasteride and adding treatments including oral minoxidil, Proscar, Viviscal, pumpkin seed oil, LLLT, and Nizoral shampoo, hoping for hair regrowth.

      community Zix + Topical Fin : Blood Test Before/After, AMA and suggestions

      in Treatment  47 upvotes 4 years ago
      A user's plan to use Zix and topical finasteride (5AR inhibitors) for hair loss, followed by blood testing before/after. The user has suggested creating a fund to cover part of the cost of their blood tests. Replies to their post discuss the effectiveness of the treatments.

      community I think I’m on to something

       24 upvotes 5 years ago
      The user shared their personal experience with hair loss, hormone imbalances, and treatments including testosterone boosters, natural estrogen blockers, and DHEA. They suggest that low-dose finasteride and natural hormone therapy could reduce hair loss with fewer side effects.

      community My Experience and a Discourse on "DUPA"

      in Treatment  9 upvotes 6 months ago
      The user discusses their hair loss experience, exploring various hypotheses including thyroid levels, vitamin D, DHEA, nutritional deficiency, diabetes, seborrheic dermatitis, lack of nutrition to hair follicles, chronic inflammation, female pattern hair loss causes, cortisol, and prolactin levels. They are currently using finasteride, beta-sitosterol, and have tried topical dutasteride and microneedling therapy.

      community Last resort attempt. Studies suggest that finasteride topically actually inhibits up to 52% scalp dht which is smiles to dut 0.5mg daily. This solution contains: fin, min, melatonin and progesterone. Trial started today.

      in Research/Science  8 upvotes 2 years ago
      The conversation discusses a last-resort hair loss treatment combining topical finasteride, minoxidil, melatonin, and progesterone, with claims that topical finasteride can inhibit up to 52% of scalp DHT. One reply clarifies that progesterone is not an anti-androgen but has anti-androgenic properties because it competes with androgens for receptors.