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GlossaryDesert Hedgehog

gene involved in hair follicle development and cell differentiation

Desert Hedgehog (DHH) is a gene that encodes a signaling protein involved in the development of various tissues, including hair follicles. It plays a crucial role in the regulation of cell growth and differentiation, particularly in the formation of the dermal papilla, which is essential for hair follicle development and cycling. Mutations or disruptions in the DHH gene can lead to hair growth disorders and contribute to conditions like alopecia.

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community nutrafol actually working somehow??

in Update 19 upvotes 7 months ago

A user reports significant improvement in scalp thinning after nearly 2 months of using Nutrafol, along with derma rolling and weekly rosemary oil application. Another user suggests the success might be due to saw palmetto in Nutrafol and shares their own experience of maintaining hair without finasteride.

community Further prolactin research....

in Research/Science 6 upvotes 9 months ago

HMI 115 did not work as expected for hair regrowth in humans, unlike in macaque monkeys. There is anticipation for further research on prolactin's role in hair loss, with expectations that pharmaceutical companies will likely solve this before universities.

community Hi i saw someone posting this and im just retyping it again tbh does anyone know whats the reason behind this!

in Chat 6 upvotes 11 months ago

Minoxidil helps hair growth on both scalp and face, but stopping it leads to hair loss on the scalp, not the face. The user questions why scalp hair can't be maintained with finasteride or androgen blockers after stopping minoxidil, despite these treatments reducing DHT damage.

community Update: 16 months deep - big 3

in Progress Pictures 407 upvotes 1 year ago

The user has seen positive results after 16 months of using topical Finasteride/Minoxidil, microneedling weekly, and Tretinoin for hair loss. There are no reported side effects, and the user advises that the effectiveness of microneedling depends on the pressure applied.

community my gains after 7 months (nuclear stack)

in Progress Pictures 1868 upvotes 2 weeks ago

The user shared impressive hair growth results after 7 months using a regimen of dutasteride, topical minoxidil, and biotin, alongside a healthy lifestyle. The conversation humorously discusses extreme and unconventional hair loss treatments, with many users expressing amazement and curiosity about the progress.

community Is this good improvement? 3-4 months in

in Is this regrowth? 479 upvotes 1 month ago

The user experienced increased hair density and thickness after 3-4 months using finasteride, minoxidil, dermastamping, ketoconazole, and biotin. They apply minoxidil right after dermastamping without any side effects or shedding.

community 1 year progress with top. min & fin + dermastamp

in Progress Pictures 2680 upvotes 2 months ago

A user shared their 1-year hair regrowth progress using topical minoxidil and finasteride, biotin, dermastamping, and keto shampoo. They reported significant improvement, looking younger, and feeling happier with their hair.

community These two strands of hair refuse to give in to DHT for some reason.

in Satire 990 upvotes 3 months ago

The conversation humorously discusses two resilient hair strands that resist DHT, with mentions of minoxidil and finasteride as ineffective treatments. Users joke about cloning the hairs and the mystery of baldness.

community Hair thinning on dutasteride vs fin? No shed phase

in Finasteride/Dutasteride 18 upvotes 4 months ago

A user switched from finasteride to dutasteride to combat hair thinning but noticed overall thinner hair without shedding. Another user suggested that hair can't thin without shedding and recommended adding finasteride pills for peace of mind.

community He turned 71 last week. It looks like his hairline proceeded as he aged. Do you think he's on fin or dut? Or maybe some ancient esoteric chinese remedy?

in Satire 315 upvotes 5 months ago

The conversation humorously speculates on whether an elderly man's good hairline is due to finasteride, dutasteride, or genetics. It also discusses the role of DHT and genetics in hair loss.

community Testosterone in Reference Range Doesn't Cause Hair Loss

in Research/Science 51 upvotes 9 months ago

Testosterone within the normal range does not significantly contribute to male pattern baldness (MPB); DHT is the main factor that can be controlled. Genetics play a crucial role in hair loss, and treatments like finasteride and dutasteride, which block DHT, can help despite potentially raising testosterone levels.

community Saying creatine causes loss on fin/dut makes no sense and this is why

in Finasteride/Dutasteride 42 upvotes 10 months ago

The conversation discusses whether creatine causes hair loss for those using finasteride or dutasteride, with some suggesting creatine might increase DHT or upregulate androgen receptors, potentially leading to hair loss. Others argue the evidence is not conclusive, citing limited studies and personal anecdotes, with some avoiding creatine as a precaution.

community Can someone explain the Dutasteride hysteria in this community?

in Finasteride/Dutasteride 58 upvotes 1 year ago

The conversation is about the double standard in the hair loss community regarding shedding when using different treatments. The conclusion is that shedding is considered normal when starting finasteride or minoxidil, but not when starting dutasteride, despite the fact that dutasteride is more effective at reducing DHT.

community (M26) My 3-month progress on Fin 1mg, Oral Min 2.5mg, and 1mm Derma rolling once every week. Happy with the results. What do you guys think?

in Progress Pictures 1 year ago

Progress achieved with finasteride, oral minoxidil and derma rolling in the span of three months. The replies discussed potential regrowth from using these treatments as well as advised seeking professional medical help for further hair loss advice.

community 8 months on Dutasteride , oral min and 2 weeks one RU58841

in Progress Pictures 38 upvotes 1 year ago

A user's 8-month progress using dutasteride, oral minoxidil, and 2 weeks of RU58841 to treat hair loss. The user is looking for feedback from others on their progress and experiences.

community 18->24 six years of Fin and Minox…. I guess we can’t all be winners 😭

in Progress Pictures 572 upvotes 2 years ago

A user named "EgyptStar81" who has been dealing with hair loss since age 15 due to genetics, chemotherapy and finasteride/minoxidil treatment. Possible solutions such as dutasteride, oral minoxidil, hair transplants and extensions were suggested.

community Why is human evolution like this 😂

in Chat 2 years ago

Why androgenic alopecia affects the scalp rather than other body parts, potential explanations for this phenomenon, treatments available to combat hair loss, and the implications of male attractiveness in modern society.

community Estrogen is an anabolic for scalp hair, if you mix it with growth stimulants such as oral minoxidil. All we need is an artificial SARM-estrogen that will work only with hair and will be invisible for the rest of the body + some next level AA only for hair – goodbye hair transplant industry

in Transgender 137 upvotes 3 years ago

Hair loss discussion mentions using estrogen mixed with growth stimulants like oral minoxidil for scalp hair growth. Idea proposed for an artificial SARM-estrogen that only affects hair without body side effects.

community 22 years since the last major development

in Technology 50 upvotes 3 years ago

The conversation discusses the lack of significant advancements in hair loss treatments since the introduction of finasteride 22 years ago, with many expressing frustration over the failure of new projects and skepticism about future developments. Some users mention hair transplants and other potential alternatives like Alfatradiol and Fluridil, but acknowledge finasteride's dominance in the market due to its effectiveness and affordability.

community The no BS guide to saving your hair without finasteride (improvement in 90% of patients in the study) with a low side effect profile or improvement in 100% of patients but a higher side effect profile and increased dosage. The future is here?

in Minoxidil 92 upvotes 4 years ago

Hair loss treatments, specifically the use of oral minoxidil in combination with micro-needling. Oral minoxidil has been found to improve hair density in 90% of patients with a low side effect profile, but using 5mg per day can result in higher side effects including hypertrichosis and edema. Other treatments mentioned include finasteride and RU58841.

community Dutasteride broked my liver (maybe)

in Finasteride/Dutasteride 8 upvotes 2 years ago

A user shared their experience with high cholesterol, glucose, and potential metabolic syndrome after using Finasteride and Dutasteride for hair loss. They plan to improve their health with diet and exercise before considering medication.